Nikta Rezakahn Khajeh1,2, Timothy L Hall3, Khurshid R Ghani4, William W Roberts4,3. 1. Deparatment of Urology, University of Michigan, 4432 Medical Science I, 1301 Catherine Street, Ann Arbor, MI, 48109-5330, USA. nkhajeh921@gmail.com. 2. Department of Urology, William Beaumont Health, Royal Oak, MI, USA. nkhajeh921@gmail.com. 3. Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. 4. Deparatment of Urology, University of Michigan, 4432 Medical Science I, 1301 Catherine Street, Ann Arbor, MI, 48109-5330, USA.
Abstract
PURPOSE: To develop a novel automated three-dimensional (3D) laser drilling algorithm to further investigate laser-stone interaction with different laser pulse modes. Comparison of post-ablative lattice architecture combined with mass of stone ablated can provide a more complete understanding of differences between pulse mode. METHODS: A 3D positioner (securing laser fiber) was programmed to create a 5 × 5 grid of drill holes spaced 1 mm apart on 15:5 cylindrical BegoStones. Beginning 0.5 mm above the stone surface, the laser fiber was activated and advanced 2 mm toward and into the stone for all 25 points. Four trials for each pulse mode [short pulse (SP), long pulse (LP), Moses Contact (MC), Moses Distance (MD)] were completed. Outcome measures were assessment of lattice preservation and mass of ablated stone. RESULTS: MC exhibited the greatest lattice preservation and least stone mass ablated (50.5 ± 2.2 mg). SP (69.4 ± 4.3 mg) and MD (70.0 ± 2.6 mg) had the greatest lattice destruction and stone mass ablated. The differences in stone ablated between MC and MD (p = 0.00003), MC and SP (p = 0.0002), and LP and MD (p = 0.004) were statistically significant. CONCLUSIONS: Consistent quantitative and qualitative differences between pulse modes were observed with a novel automated 3D laser drilling algorithm applied to BegoStone. The laser drilling algorithm developed here can be used to further enhance mechanistic understanding of laser-stone interactions and facilitate selection of appropriate laser pulse modes to balance precision and efficiency across the range of laser lithotripsy techniques.
PURPOSE: To develop a novel automated three-dimensional (3D) laser drilling algorithm to further investigate laser-stone interaction with different laser pulse modes. Comparison of post-ablative lattice architecture combined with mass of stone ablated can provide a more complete understanding of differences between pulse mode. METHODS: A 3D positioner (securing laser fiber) was programmed to create a 5 × 5 grid of drill holes spaced 1 mm apart on 15:5 cylindrical BegoStones. Beginning 0.5 mm above the stone surface, the laser fiber was activated and advanced 2 mm toward and into the stone for all 25 points. Four trials for each pulse mode [short pulse (SP), long pulse (LP), Moses Contact (MC), Moses Distance (MD)] were completed. Outcome measures were assessment of lattice preservation and mass of ablated stone. RESULTS: MC exhibited the greatest lattice preservation and least stone mass ablated (50.5 ± 2.2 mg). SP (69.4 ± 4.3 mg) and MD (70.0 ± 2.6 mg) had the greatest lattice destruction and stone mass ablated. The differences in stone ablated between MC and MD (p = 0.00003), MC and SP (p = 0.0002), and LP and MD (p = 0.004) were statistically significant. CONCLUSIONS: Consistent quantitative and qualitative differences between pulse modes were observed with a novel automated 3D laser drilling algorithm applied to BegoStone. The laser drilling algorithm developed here can be used to further enhance mechanistic understanding of laser-stone interactions and facilitate selection of appropriate laser pulse modes to balance precision and efficiency across the range of laser lithotripsy techniques.
Authors: Daniel A Wollin; Anika Ackerman; Chen Yang; Tony Chen; Walter Neal Simmons; Glenn M Preminger; Michael E Lipkin Journal: Urology Date: 2017-01-16 Impact factor: 2.649
Authors: Ronald Sroka; Thomas Pongratz; Gabriel Scheib; Wael Khoder; Christian G Stief; Thomas Herrmann; Udo Nagele; Markus J Bader Journal: World J Urol Date: 2015-02-25 Impact factor: 4.226
Authors: Brian R Matlaga; Ben Chew; Brian Eisner; Mitchell Humphreys; Bodo Knudsen; Amy Krambeck; Dirk Lange; Michael Lipkin; Nicole L Miller; Manoj Monga; Vernon Pais; Roger L Sur; Ojas Shah Journal: J Endourol Date: 2017-11-27 Impact factor: 2.942
Authors: Casey A Dauw; Laika Simeon; Abdulrahman F Alruwaily; Francesco Sanguedolce; John M Hollingsworth; William W Roberts; Gary J Faerber; J Stuart Wolf; Khurshid R Ghani Journal: J Endourol Date: 2015-08-21 Impact factor: 2.942