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Literature DB >> 3610157

The fragile site (16)(q22). II. Sister chromatid exchanges.

Abstract

In the lymphocytes of heterozygous carriers of the rare autosomal fragile site (16)(q22) an exceptionally high frequency of sister chromatid exchanges was demonstrated at the induced fragile site by means of simultaneous berenil and BrdU treatment of the cultures. The rate of sister chromatid exchanges at q22 is also increased in the fragile chromosome 16 by treating the cells with BrdU alone. The possible reasons for the preferential occurrence of induced and spontaneous sister chromatid exchanges at fra (16)(q22) are discussed.

Entities: Chemical Disease Gene

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Year: 1987 PMID： 3610157 DOI： 10.1007/bf00272446

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

18 in total

1. Fine structure of 33 258 H-treated chromosomes.

Authors: H G Schwarzacher; A Gropp; F Ruzicka
Journal: Hum Genet Date: 1976-08-30 Impact factor: 4.132

2. An investigation of human sperm pronuclear chromosome "gaps" using scanning electron microscopy.

Authors: J E Chernos; J B Rattner; R H Martin
Journal: Cytogenet Cell Genet Date: 1986

3. Localization of sister chromatid exchanges in human chromosomes.

Authors: S A Latt
Journal: Science Date: 1974-07-05 Impact factor: 47.728

4. The fragile X: a scanning electron microscope study.

Authors: C J Harrison; E M Jack; T D Allen; R Harris
Journal: J Med Genet Date: 1983-08 Impact factor: 6.318

5. BrdU-sensitive fragile site on long arm of chromosome 16.

Authors: G Croci
Journal: Am J Hum Genet Date: 1983-05 Impact factor: 11.025

6. Distribution of sister chromatid exchanges in the euchromatin and heterochromatin of the Indian muntjac.

Authors: A V Carrano; S Wolff
Journal: Chromosoma Date: 1975-12-29 Impact factor: 4.316

7. The use of distamycin A in human lymphocyte cultures.

Authors: M Schmid; D A Hungerford; A Poppen; W Engel
Journal: Hum Genet Date: 1984 Impact factor: 4.132

8. Heritable fragile sites on human chromosomes. XI. Factors affecting expression of fragile sites at 10q25, 16q22, and 17p12.

Authors: G R Sutherland; P B Jacky; E G Baker
Journal: Am J Hum Genet Date: 1984-01 Impact factor: 11.025

9. [Mechanism of action of trypanocide diamidines. Importance of base composition in the berenil-polynucleotides association].

Authors: B Festy; A M Lallemant; G Riou; C Brack; E Delain
Journal: C R Acad Hebd Seances Acad Sci D Date: 1970-08-17

10. Determination of the baseline sister chromatid exchange frequency in human and mouse peripheral lymphocytes using monoclonal antibodies and very low doses of bromodeoxyuridine.

Authors: J D Tucker; M L Christensen; C L Strout; A V Carrano
Journal: Cytogenet Cell Genet Date: 1986

5 in total

The fragile site (16)(q22). II. Sister chromatid exchanges.

1. Fine structure of 33 258 H-treated chromosomes.

2. An investigation of human sperm pronuclear chromosome "gaps" using scanning electron microscopy.

3. Localization of sister chromatid exchanges in human chromosomes.

4. The fragile X: a scanning electron microscope study.

5. BrdU-sensitive fragile site on long arm of chromosome 16.

6. Distribution of sister chromatid exchanges in the euchromatin and heterochromatin of the Indian muntjac.

7. The use of distamycin A in human lymphocyte cultures.

8. Heritable fragile sites on human chromosomes. XI. Factors affecting expression of fragile sites at 10q25, 16q22, and 17p12.

9. [Mechanism of action of trypanocide diamidines. Importance of base composition in the berenil-polynucleotides association].

10. Determination of the baseline sister chromatid exchange frequency in human and mouse peripheral lymphocytes using monoclonal antibodies and very low doses of bromodeoxyuridine.

1. Induction of distamycin A-inducible rare fragile sites and increased sister chromatid exchanges at the fragile site.

2. "Spontaneous" FRA16B is a hot spot for sister chromatid exchanges.

3. Increased frequencies of sister chromatid exchanges at common fragile sites (1)(q42) and (19)(q13).

4. Dose-response function for Painter's SCE-model.

5. Sister chromatid exchanges are preferentially induced at expressed and nonexpressed common fragile sites.