Literature DB >> 3609059

99mTc-HMPAO as a tumour blood flow agent.

P A Hammersley, V R McCready, J W Babich, G Coghlan.   

Abstract

The cerebral blood flow agent, 99mTc-HMPAO ('CeretecTM') has been investigated to see if it can be used to estimate tumour blood flow. Its distribution in Balb/c mice bearing either a subcutaneously implanted sarcoma or a plasmacytoma has been shown to be similar to that of 86RbCl. The changes in peripheral blood flow caused by the beta-blocker, propranolol, and by Nembutal anaesthesia, are manifested equally by 99mTc-HMPAO and 86Rb. We conclude, therefore, that HMPAO may be useful in estimating tumour perfusion.

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Year:  1987        PMID： 3609059     DOI： 10.1007/bf00256023

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  7 in total

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Journal:  Am J Physiol       Date:  1958-04

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Authors:  G D Zanelli; J F Fowler
Journal:  Cancer Res       Date:  1974-06       Impact factor: 12.701

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Journal:  Nucl Med Commun       Date:  1985-09       Impact factor: 1.690

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Authors:  P M GULLINO; F H GRANTHAM
Journal:  J Natl Cancer Inst       Date:  1961-12       Impact factor: 13.506

5.  Propranolol hydrochloride enhancement of tumor perfusion and uptake of gallium-67 in a mouse sarcoma.

Authors:  P Bomber; R McCready; P Hammersley
Journal:  J Nucl Med       Date:  1986-02       Impact factor: 10.057

6.  99mTc-propylene amine oxime (99mTc-PnAO); a potential brain radiopharmaceutical.

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Journal:  Eur J Nucl Med       Date:  1984

7.  The effect of anaesthetics on blood perfusion in transplanted mouse tumours.

Authors:  G D Zanelli; P B Lucas; J F Fowler
Journal:  Br J Cancer       Date:  1975-09       Impact factor: 7.640
  7 in total
  12 in total

1.  Evaluation of primary lung carcinoma using technetium 99m-hexamethylpropylene amine oxime: preliminary clinical experience.

Authors:  M Oshima; K Itoh; S Okae; M Tadokoro; Y Kodama; S Sakuma
Journal:  Eur J Nucl Med       Date:  1990

2.  Accumulation of 99mTc-HM-PAO in photon deficient areas in bone scan of bone metastasis from hepatocellular carcinoma.

Authors:  N Otsuka; M Fukunaga; K Morita; S Ono; K Nagai; T Tomomitsu; S Yanagimoto; H Mimura; S Yamamoto; Y Hirano
Journal:  Ann Nucl Med       Date:  1992-11       Impact factor: 2.668

Review 3.  The role of nuclear medicine in oncology.

Authors:  H J Biersack; B Briele; A L Hotze; P Oehr; L Qian; M A Mekkawy; W J Shih
Journal:  Ann Nucl Med       Date:  1992-08       Impact factor: 2.668

4.  The behavior of 99mTc-hexamethylpropyleneamineoxime (99mTc-HMPAO) in blood and brain.

Authors:  K Nakamura; Y Tukatani; A Kubo; S Hashimoto; Y Terayama; T Amano; F Goto
Journal:  Eur J Nucl Med       Date:  1989

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Authors:  B Deehan; P Carnochan; M Trivedi; A Tombs
Journal:  Eur J Nucl Med       Date:  1993-02

6.  Quantitative single-photon emission tomography for tumour blood flow measurement in bronchial carcinoma.

Authors:  N P Rowell; M A Flower; B Cronin; V R McCready
Journal:  Eur J Nucl Med       Date:  1993-07

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Journal:  Eur J Nucl Med       Date:  1988

8.  Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology.

Authors:  Danielle Mandikian; Isabel Figueroa; Amy Oldendorp; Hanine Rafidi; Sheila Ulufatu; Michelle G Schweiger; Jessica A Couch; Noel Dybdal; Sean B Joseph; Saileta Prabhu; Gregory Z Ferl; C Andrew Boswell
Journal:  AAPS J       Date:  2018-10-08       Impact factor: 4.009

9.  Effects of anti-VEGF on predicted antibody biodistribution: roles of vascular volume, interstitial volume, and blood flow.

Authors:  C Andrew Boswell; Gregory Z Ferl; Eduardo E Mundo; Daniela Bumbaca; Michelle G Schweiger; Frank-Peter Theil; Paul J Fielder; Leslie A Khawli
Journal:  PLoS One       Date:  2011-03-15       Impact factor: 3.240

10.  Technetium-99m HMPAO and SPECT in the assessment of blood flow in human lung tumours.

Authors:  N P Rowell; V R McCready; D Tait; M A Flower; B Cronin; G E Adams; A Horwich
Journal:  Br J Cancer       Date:  1989-01       Impact factor: 7.640
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