Literature DB >> 36034721

Diffuse Spinal Hyperostosis Causing Severe Spinal Stenosis and Thoracic Myelopathy.

Daniel Alsoof1, George Anderson2, Kevin J DiSilvestro1, Christopher L McDonald1, Eren O Kuris1, Alan H Daniels1.   

Abstract

Introduction: Spinal stenosis has a wide range of causes including disc herniation, facet hypertrophy, degenerative spondylosis, facet cyst, ossification of the ligamentum flavum (OLF) and ossification of the posterior longitudinal ligament (OPLL). We present three cases of diffuse spinal hyperostosis causing severe spinal stenosis and myelopathy, which demonstrate a unique association between obesity and a novel syndrome of hyperostosis. Case Presentation: This report describes 3 morbidly obese patients with diffuse spinal hyperostosis causing critical thoracic stenosis. Their presenting complaints focus on lower extremity weakness and the CT/MRI imaging is striking for diffuse hyper-ossification at thoracic levels. Two patients were subsequently managed with spinal decompression, and one patient was managed non-operatively. Discussion: Metabolic changes associated with obesity may result in diffuse hyperostosis with ligament ossification and spinal stenosis. Pre-operative imaging is essential to identify the degree of ossification and potential dural involvement as this may complicate management.

Entities:  

Keywords:  OLF; spinal hyperostosis; spinal stenosis; thoracic myelopathy

Year:  2022        PMID: 36034721      PMCID: PMC9404251          DOI: 10.52965/001c.37832

Source DB:  PubMed          Journal:  Orthop Rev (Pavia)        ISSN: 2035-8164


  18 in total

Review 1.  Double Crush Syndrome.

Authors:  Patrick M Kane; Alan H Daniels; Edward Akelman
Journal:  J Am Acad Orthop Surg       Date:  2015-09       Impact factor: 3.020

2.  Is congenital bony stenosis of the cervical spine associated with congenital bony stenosis of the thoracic spine? An anatomic study of 1072 human cadaveric specimens.

Authors:  Navkirat S Bajwa; Jason O Toy; Nicholas U Ahn
Journal:  J Spinal Disord Tech       Date:  2013-02

3.  Clinical relation among dural adhesion, dural ossification, and dural laceration in the removal of ossification of the ligamentum flavum.

Authors:  Jeong-Hyuk Ju; Sung-Jun Kim; Kyung-Hyun Kim; Dal-Sung Ryu; Jeong-Yoon Park; Dong-Kyu Chin; Keun-Su Kim; Yong-Eun Cho; Sung-Uk Kuh
Journal:  Spine J       Date:  2017-09-20       Impact factor: 4.166

4.  Establishment of parameters for congenital thoracic stenosis: a study of 700 postmortem specimens.

Authors:  Navkirat S Bajwa; Jason O Toy; Nicholas U Ahn
Journal:  Clin Orthop Relat Res       Date:  2012-07-04       Impact factor: 4.176

5.  Ossification of the Ligamentum Flavum at the Thoracic and Lumbar Region in an Achondroplastic Patient.

Authors:  H Bahadir Gokcen; Cagatay Ozturk
Journal:  World Neurosurg       Date:  2019-03-13       Impact factor: 2.104

6.  Thoracic ossification of ligamentum flavum caused by skeletal fluorosis.

Authors:  Wenbao Wang; Linghua Kong; Heyuan Zhao; Ronghua Dong; Jianjiang Li; Zhanhua Jia; Ning Ji; Shucai Deng; Zhiming Sun; Jing Zhou
Journal:  Eur Spine J       Date:  2006-10-31       Impact factor: 3.134

7.  Clinical Features of Thoracic Spinal Stenosis-associated Myelopathy: A Retrospective Analysis of 427 Cases.

Authors:  Xiaofei Hou; Chuiguo Sun; Xiaoguang Liu; Zhongjun Liu; Qiang Qi; Zhaoqing Guo; Weishi Li; Yan Zeng; Zhongqiang Chen
Journal:  Clin Spine Surg       Date:  2016-03       Impact factor: 1.876

8.  Surgical treatment of ossification of the ligamentum flavum associated with dural ossification in the thoracic spine.

Authors:  Zhong Yang; Yuan Xue; Chao Zhang; Qin Dai; Huifang Zhou
Journal:  J Clin Neurosci       Date:  2012-12-23       Impact factor: 1.961

9.  Thoracic myelopathy caused by ossification of the ligamentum flavum: a report of 18 cases.

Authors:  Karim Ben Hamouda; Hafedh Jemel; Slim Haouet; Moncef Khaldi
Journal:  J Neurosurg       Date:  2003-09       Impact factor: 5.115

Review 10.  Ossification of the ligamentum flavum.

Authors:  Dong Ki Ahn; Song Lee; Sang Ho Moon; Kyung Hwan Boo; Byung Kwon Chang; Jae Il Lee
Journal:  Asian Spine J       Date:  2014-02-06
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