Literature DB >> 26885607

Clinical Features of Thoracic Spinal Stenosis-associated Myelopathy: A Retrospective Analysis of 427 Cases.

Xiaofei Hou1, Chuiguo Sun, Xiaoguang Liu, Zhongjun Liu, Qiang Qi, Zhaoqing Guo, Weishi Li, Yan Zeng, Zhongqiang Chen.   

Abstract

STUDY
DESIGN: This was a retrospective review.
OBJECTIVE: The aim of this study was to examine the epidemiological characteristics and causes of spinal cord compression in thoracic spinal stenosis (TSS). SUMMARY OF BACKGROUND DATA: As the thoracic spinal canal is relatively narrow and the thoracic cord has a poor blood supply, severe neurological symptoms may develop if TSS is not treated promptly. However, as it is rare, TSS is less often studied and its clinical features are often not recognized.
METHODS: Between 2005 and 2012, 427 patients diagnosed with TSS underwent surgery in our department. The male to female ratio was 1.4:1. The mean age was 53 years. The most reported symptom was motor deficit in the lower extremities (347 cases, 81%), followed by sensory deficit in the lower limbs (271 cases, 64%). Falls were the most common trigger of acute symptoms (29 cases, 7%). Preoperative imaging results of each case were reviewed to summarize the causes and site of cord compression and coexisting spinal diseases.
RESULTS: The most reported compressive factor was ossification of the ligamentum flavum (OLF), which implicated in 309 cases, followed by thoracic disk herniation (TDH) and ossification of the posterior longitudinal ligament (OPLL). The most common site of OLF and TDH was T9-L1 (56% and 89%, respectively), whereas OPLL was mainly found at T1-8 (90%). Forty-seven patients (11%) had coexisting lumbar spinal disease and 64 (15%) had cervical disease.
CONCLUSIONS: Onset of TSS was generally insidious but may be triggered acutely by apparently trivial events. Myelopathy mainly affected the lower limbs. The most common cause was OLF in the lower thoracic spine. Cervical or lumbar spinal disease was often also evident; therefore, comprehensive clinical assessment is required to avoid delays in diagnosis and treatment.

Entities:  

Mesh:

Year:  2016        PMID: 26885607     DOI: 10.1097/BSD.0000000000000081

Source DB:  PubMed          Journal:  Clin Spine Surg        ISSN: 2380-0186            Impact factor:   1.876


  29 in total

1.  Two novel BMP-2 variants identified in patients with thoracic ossification of the ligamentum flavum.

Authors:  Xiaochen Qu; Zhongqiang Chen; Dongwei Fan; Shen Xiang; Chuiguo Sun; Yan Zeng; Weishi Li; Zhaoqing Guo; Qiang Qi; Woquan Zhong; Yun Jiang
Journal:  Eur J Hum Genet       Date:  2017-02-01       Impact factor: 4.246

2.  The bridge crane technique for the treatment of the severe thoracic ossification of the ligamentum flavum with myelopathy.

Authors:  Jingchuan Sun; Kaiqiang Sun; Jiangang Shi; Ximing Xu; Yuan Wang; Qingjie Kong
Journal:  Eur Spine J       Date:  2018-06-29       Impact factor: 3.134

3.  Kinematic evaluation of thoracic spinal cord sagittal diameter and the space available for cord using weight-bearing kinematic magnetic resonance imaging.

Authors:  Permsak Paholpak; Aidin Abedi; Rattanaporn Chamnan; Kunlavit Chantarasirirat; Koji Tamai; Zorica Buser; Jeffrey C Wang
Journal:  Spinal Cord       Date:  2018-09-24       Impact factor: 2.772

Review 4.  A systematic review of complications in thoracic spine surgery for ossification of ligamentum flavum.

Authors:  Xiaofei Hou; Zhongqiang Chen; Chuiguo Sun; Guangwu Zhang; Sijun Wu; Zheng Liu
Journal:  Spinal Cord       Date:  2017-12-28       Impact factor: 2.772

5.  Prevalence of thoracic spine lesions masquerading as cauda equina syndrome: yield of a novel magnetic resonance imaging protocol.

Authors:  Katherine Stolper; James Clark Haug; Chad Todd Christensen; Kathleen Michelle Samsey; Michael David April
Journal:  Intern Emerg Med       Date:  2016-11-04       Impact factor: 3.397

6.  Association analysis and functional study of COL6A1 single nucleotide polymorphisms in thoracic ossification of the ligamentum flavum in the Chinese Han population.

Authors:  Xiaochen Qu; Xiaofei Hou; Zhongqiang Chen; Guanghui Chen; Tianqi Fan; Xiaoxi Yang
Journal:  Eur Spine J       Date:  2021-07-21       Impact factor: 3.134

7.  Surgical strategy for non-continuous thoracic spinal stenosis: one- or two-stage surgery?

Authors:  Longjie Wang; Hui Wang; Zhongqiang Chen; Chuiguo Sun; Weishi Li
Journal:  Int Orthop       Date:  2021-01-11       Impact factor: 3.075

8.  The screening process of a patient with low back pain and suspected thoracic myelopathy: a case report.

Authors:  Guillaume Christe; Toby Hall
Journal:  J Man Manip Ther       Date:  2017-01-23

9.  [Study on the safety and effectiveness of low-dose tranexamic acid in operation of multi-level continuous thoracic ossification of ligament flavum].

Authors:  Qian Chen; Qingsong Zhou; Junfei Feng; Qingyan Zhang; Yuling Li; Jianguang Zhang; Yuqing Ren; Lu Chen; Peng Wei
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2021-07-15

10.  Age at Diagnosis and Baseline Myelomalacia Sign Predict Functional Outcome After Spinal Meningioma Surgery.

Authors:  Johannes Wach; Mohammed Banat; Patrick Schuss; Erdem Güresir; Hartmut Vatter; Jasmin Scorzin
Journal:  Front Surg       Date:  2021-07-02
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