Literature DB >> 36000011

En Masse Excision and Curettage for Periarticular Gouty Tophi of the Hands.

Matthew Doscher1,2, Bryan G Beutel1, Andrew Lovy1, Brandon Alba2,3, Charles Melone1.   

Abstract

Background: Despite increasing disease prevalence, there remains a paucity of data examining surgical treatments for gouty tophi. This article assesses en masse excision and curettage of articular tophi involving the hands and shows that carefully planned and precisely executed surgery can consistently alleviate pain, preserve function, and enhance the aesthetics of afflicted hands.
Methods: A retrospective review was conducted of all consecutive patients who underwent surgical excision of tophaceous deposits from the upper extremity. All patients had an established diagnosis of gout and had been treated with urate-lowering medication. All tophi were substantive in size and were causing significant digital joint dysfunction and disfigurement with variable skin ulcerations.
Results: The study group included 12 patients with 24 tophaceous deposits excised from the metacarpal and interphalangeal joints; 2 deposits were also concomitantly excised from the wrist and 2 from the elbow. The study group included 8 men and 4 women, with an average age of 67 years. Follow-up evaluation ranged from 2 to 15 years. All patients underwent successful tophus excision with restoration of tendon excursion and joint mobility without wound complications. All regained high levels of function, and all reported satisfaction with their outcome. On follow-up for as long as 15 years, recurrence has not been observed and secondary surgery has not proved necessary. Conclusions: This study indicates that surgical excision of articular tophi of the hands can provide long-term improvement in function and aesthetics with minimal risk of wound complications or recurrence.
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Entities:  

Keywords:  gout; hand; tophi

Year:  2022        PMID: 36000011      PMCID: PMC9361386     

Source DB:  PubMed          Journal:  Eplasty        ISSN: 1937-5719


  12 in total

1.  Management of tophaceous gout of the distal interphalangeal joint.

Authors:  C S Mudgal
Journal:  J Hand Surg Br       Date:  2005-10-21

2.  2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia.

Authors:  Dinesh Khanna; John D Fitzgerald; Puja P Khanna; Sangmee Bae; Manjit K Singh; Tuhina Neogi; Michael H Pillinger; Joan Merill; Susan Lee; Shraddha Prakash; Marian Kaldas; Maneesh Gogia; Fernando Perez-Ruiz; Will Taylor; Frédéric Lioté; Hyon Choi; Jasvinder A Singh; Nicola Dalbeth; Sanford Kaplan; Vandana Niyyar; Danielle Jones; Steven A Yarows; Blake Roessler; Gail Kerr; Charles King; Gerald Levy; Daniel E Furst; N Lawrence Edwards; Brian Mandell; H Ralph Schumacher; Mark Robbins; Neil Wenger; Robert Terkeltaub
Journal:  Arthritis Care Res (Hoboken)       Date:  2012-10       Impact factor: 4.794

3.  Different surgical approaches to treat chronic tophaceous gout in the hand: our experience.

Authors:  Massimiliano Tripoli; Andrea Rainer Falcone; Carmela Mossuto; Francesco Moschella
Journal:  Tech Hand Up Extrem Surg       Date:  2010-09

4.  Tophaceous gout involving the proximal interphalangeal joint.

Authors:  R H Gelberman; D H Doty; M L Hamer
Journal:  Clin Orthop Relat Res       Date:  1980 Mar-Apr       Impact factor: 4.176

5.  Febuxostat compared with allopurinol in patients with hyperuricemia and gout.

Authors:  Michael A Becker; H Ralph Schumacher; Robert L Wortmann; Patricia A MacDonald; Denise Eustace; William A Palo; Janet Streit; Nancy Joseph-Ridge
Journal:  N Engl J Med       Date:  2005-12-08       Impact factor: 91.245

6.  Effect of urate-lowering therapy on the velocity of size reduction of tophi in chronic gout.

Authors:  Fernando Perez-Ruiz; Marcelo Calabozo; Jose I Pijoan; Ana M Herrero-Beites; Ana Ruibal
Journal:  Arthritis Rheum       Date:  2002-08

7.  Timing of intra-lesion shaving for surgical treatment of chronic tophus.

Authors:  Su-Shin Lee; Meng-Chum Chen; Yun-Hui Chou; Sin-Daw Lin; Chung-Sheng Lai; Ying-Cheng Chen
Journal:  J Plast Reconstr Aesthet Surg       Date:  2013-05-21       Impact factor: 2.740

Review 8.  Treatment of tophaceous gout: When medication is not enough.

Authors:  Isaac R Kasper; Matthew D Juriga; John M Giurini; Robert H Shmerling
Journal:  Semin Arthritis Rheum       Date:  2016-01-29       Impact factor: 5.532

Review 9.  Epidemiology of gout.

Authors:  Edward Roddy; Hyon K Choi
Journal:  Rheum Dis Clin North Am       Date:  2014-02-19       Impact factor: 2.670

10.  Tophi and frequent gout flares are associated with impairments to quality of life, productivity, and increased healthcare resource use: Results from a cross-sectional survey.

Authors:  Puja P Khanna; George Nuki; Thomas Bardin; Anne-Kathrin Tausche; Anna Forsythe; Amir Goren; Jeffrey Vietri; Dinesh Khanna
Journal:  Health Qual Life Outcomes       Date:  2012-09-22       Impact factor: 3.186

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