Background: Seminal classifications of degenerative arthritis of the shoulder (DAS) describe either cuff tear arthropathy in the coronal plane or primary osteoarthritis in the cross-sectional plane. None consider a biplanar eccentricity. Purpose/Hypothesis: The purpose of this study was to investigate humeroscapular alignment (HSA) of patients with DAS in both the anteroposterior (A-P) and superoinferior (S-I) planes on computed tomography (CT) after 3-dimensional (3D) reconstruction and develop a classification based on biplanar HSA in 9 quadrants. It was hypothesized that biplanar eccentricity would occur frequently. Study Design: Cross-sectional study; Level of evidence, 3. Methods: The authors analyzed 130 CT scans of patients who had undergone shoulder arthroplasty. The glenoid center, trigonum, and inferior angle of the scapula were aligned in a single plane using 3D reconstruction software. Subluxation of the HSA was measured as the distance from the center of rotation of the humeral head to the scapular axis (line from trigonum through glenoid center) and was expressed as a percentage of the radius of the humeral head in both the A-P and the S-I directions. HSA was described in terms of A-P alignment first (posterior/central/anterior), then S-I alignment (superior/central/inferior), for a total of 9 different alignment combinations. Additionally, glenoid erosion was graded 1-3. Results: Subluxation of the HSA was 74.1% posterior to 23.5% anterior in the A-P direction and 17.2% inferior to 68.6% superior in the S-I direction. A central HSA was calculated as between 20% posterior to 5% anterior (A-P) and 5% inferior to 20% superior (S-I), after a graphical analysis. Posterior subluxation >60% of the radius was labeled as extraposterior, and static acetabularization was labeled as extrasuperior. Overall, 21 patients had central-central, 40 centrosuperior, and 1 centroinferior alignment. Of 60 shoulders with posterior subluxation, alignment was posterocentral in 31, posterosuperior in 25, and posteroinferior in 5. There were 3 patients with anterocentral and 4 anterosuperior subluxation; in addition, 4 cases with extraposterior and 17 with extrasuperior subluxation were identified. Conclusion: There was a high prevalence of biplanar eccentricity in DAS. The 3D classification system using combined HSA and glenoid erosion can be applied to describe DAS comprehensively.
Background: Seminal classifications of degenerative arthritis of the shoulder (DAS) describe either cuff tear arthropathy in the coronal plane or primary osteoarthritis in the cross-sectional plane. None consider a biplanar eccentricity. Purpose/Hypothesis: The purpose of this study was to investigate humeroscapular alignment (HSA) of patients with DAS in both the anteroposterior (A-P) and superoinferior (S-I) planes on computed tomography (CT) after 3-dimensional (3D) reconstruction and develop a classification based on biplanar HSA in 9 quadrants. It was hypothesized that biplanar eccentricity would occur frequently. Study Design: Cross-sectional study; Level of evidence, 3. Methods: The authors analyzed 130 CT scans of patients who had undergone shoulder arthroplasty. The glenoid center, trigonum, and inferior angle of the scapula were aligned in a single plane using 3D reconstruction software. Subluxation of the HSA was measured as the distance from the center of rotation of the humeral head to the scapular axis (line from trigonum through glenoid center) and was expressed as a percentage of the radius of the humeral head in both the A-P and the S-I directions. HSA was described in terms of A-P alignment first (posterior/central/anterior), then S-I alignment (superior/central/inferior), for a total of 9 different alignment combinations. Additionally, glenoid erosion was graded 1-3. Results: Subluxation of the HSA was 74.1% posterior to 23.5% anterior in the A-P direction and 17.2% inferior to 68.6% superior in the S-I direction. A central HSA was calculated as between 20% posterior to 5% anterior (A-P) and 5% inferior to 20% superior (S-I), after a graphical analysis. Posterior subluxation >60% of the radius was labeled as extraposterior, and static acetabularization was labeled as extrasuperior. Overall, 21 patients had central-central, 40 centrosuperior, and 1 centroinferior alignment. Of 60 shoulders with posterior subluxation, alignment was posterocentral in 31, posterosuperior in 25, and posteroinferior in 5. There were 3 patients with anterocentral and 4 anterosuperior subluxation; in addition, 4 cases with extraposterior and 17 with extrasuperior subluxation were identified. Conclusion: There was a high prevalence of biplanar eccentricity in DAS. The 3D classification system using combined HSA and glenoid erosion can be applied to describe DAS comprehensively.
The characteristics of glenoid morphology and alignment in degenerative arthritis of the
shoulder (DAS) have typically been classified according to primary osteoarthritis (OA)
in the cross-sectional plane or cuff tear arthropathy (CTA) in the coronal plane. The
widely used modified Walch classification of glenohumeral OA uses cross-sectional
computed tomography (CT).
CTA is categorized using the Hamada classification, which relies on
anteroposterior (AP) x-ray images.
The Favard classification
further classifies the resulting glenoid wear also using AP x-rays (Table 1).
Table 1
Summary of the Modified Walch,
Hamada,
and Favard
Classifications of OA and CTA
Summary of the Modified Walch,
Hamada,
and Favard
Classifications of OA and CTAA-P, anteroposterior; CT, computed tomography; CTA, cuff tear
arthropathy; OA, osteoarthritis.These commonly used seminal classification systems for DAS are based on 2-dimensional
descriptions; however, none consider biplanar eccentricity. Several studies have since
investigated the glenoid wear patterns in DAS in great detail and have found a combined
eccentricity of the erosion sites.
Biplanar eccentricity in shoulder arthritis has also been documented in terms of
humeroscapular alignment (HSA); Jacxsens et al
showed, on average, a posteroinferior alignment in cases classified as Walch type
B1. However, there are little data regarding HSA in 3 dimensions in DAS.The purpose of the present study was to investigate HSA in both the anteroposterior (A-P)
and the superoinferior (S-I) planes in patients with DAS and to determine whether
existing classifications describe the disease comprehensively. We aimed to create a
3-dimensional (3D) CT classification that encompasses alignment in both planes as well
as glenoid erosion. We hypothesized that biplanar eccentricity would be found
frequently.
Methods
Study Population
For this descriptive cohort study, we identified patients who had received a
primary shoulder prosthesis (total shoulder arthroplasty, reverse shoulder
arthroplasty, or hemiprosthesis) between 2009 and 2020 at the Department of
Orthopaedic Sports Medicine of the University Hospital Rechts der Isar in Munich
using a database search. Operative reports were assessed for a diagnosis of DAS
(as type OA or CTA). Shoulders with diagnoses other than CTA or OA or without
the availability of CT scans were excluded from the investigation. Of 299
shoulders undergoing primary shoulder replacement, 243 had a diagnosis of DAS.
For 135 of these cases preoperative CT scans, performed according to a
standardized in-house protocol (slice thickness, 0.9 mm; pitch, 0.39; tube
current, 82 mA [range, 50-115 mA]; tube voltage, 120 kV), were available for
analysis. All CT scans were taken less than 6 months before surgery. Five CT
scans had to be excluded from the analysis: 2 for inadequate exposure of the
scapula, 1 for movement artifact, and 2 for extreme erosion, which did not allow
for reliable placement of the landmarks for measurement. The remaining CT scans
of 130 shoulders were included in the study.Demographically, the study patients had a mean age of 69.7 years (range, 38-88
years), and 60 (46%) were male. The diagnosis leading to arthroplasty had been
documented as OA in 52 cases (40%) and CTA in 78 cases (60%).
Measurements
The analysis of the CT scans was performed by 2 experienced orthopaedic residents
(B.D.K. and M.H.) with an interest in shoulder surgery, using a standardized
self-developed protocol that was adapted from methods found in the literature.
First, glenoid morphology was described using the existing
classifications for shoulder OA (modified Walch,
Favard,
and Hamada
), as has previously been done using CT.
This was done in consensus between the 2 observers.Next, we used clinical 3D medical image viewing software (IDS7 Workstation
Version 22.2; Sectra) to align the glenoid center, trigonum, and inferior angle
of the scapula in a single plane. This reconstruction has previously been
described as the scapular plane.
To ascertain the glenoid center, the midpoint was defined in the
cross-sectional and coronal planes, disregarding osteophytes. The scapular axis
was defined as a line passing through the scapular trigonum and glenoid center,
in corroboration with previous work
(Figure 1).
Placing a best-fit circle on the humeral head that followed the articular
surface (where intact) and reliably intersected preserved extra-articular
landmarks at the borders of the articular surface allowed an accurate
determination of the center of rotation and size of the humeral head.
The center of rotation of the humeral head was always determined at the
widest part of the ellipse of the humeral head in the coronal and
cross-sectional views of the scapular plane, respectively, and then translated
to the level of the scapular axis. This was particularly relevant to determine
the center of rotation accurately in cases with a high degree of
subluxation.
Figure 1.
A 3-dimensional (3D) computed tomography reconstruction illustrating the
scapular plane using the trigonum, glenoid center, and inferior angle of
the scapula as landmarks. The scapular axis is the line passing from the
trigonum through the glenoid center in this plane. The eccentricity of
the center of rotation of the humeral head was measured as the distance
to the scapular axis in both the anteroposterior (A-P) and
superoinferior (S-I) directions.
A 3-dimensional (3D) computed tomography reconstruction illustrating the
scapular plane using the trigonum, glenoid center, and inferior angle of
the scapula as landmarks. The scapular axis is the line passing from the
trigonum through the glenoid center in this plane. The eccentricity of
the center of rotation of the humeral head was measured as the distance
to the scapular axis in both the anteroposterior (A-P) and
superoinferior (S-I) directions.The amount of subluxation of the humeral head was then determined by measuring
the distance of the center of rotation of the humeral head from the scapular
axis in both the A-P and the S-I directions, as has previously been reported
(Figure 2). To
correct for patient size, this was expressed as a percentage of the radius of
the humeral head (similar to the method of describing subluxation in terms of diameter
) (Figure 3) in
the corresponding plane using the following formula:
Figure 2.
Measurement of humeroscapular alignment on (A) coronal plane and (B and
C) cross-sectional plane computed tomography scans, after reconstruction
of the scapular plane in 3 dimensions. (B) The center of rotation of the
humeral head is determined at the widest part of the head and (C) is
then translated down to the level of the scapular axis for measurement
of subluxation. (D) Where there is higher-grade erosion with partial
humeral head collapse and osteophytes, measurement is more challenging.
Osteophytes (red arrow), whether on the humeral or glenoid side, must be
disregarded. The center of rotation is determined with the aid of the
intact outer margins of the humeral joint surface (blue stars).
Figure 3.
Method for determining the percentage of subluxation, s,
of the center of rotation of the humeral head from the scapular axis,
ax, relative to the radius, r,
using the given formula.
When calculated for each plane, respectively, this created vector coordinates
where (0%, 0%) is the center.Measurement of humeroscapular alignment on (A) coronal plane and (B and
C) cross-sectional plane computed tomography scans, after reconstruction
of the scapular plane in 3 dimensions. (B) The center of rotation of the
humeral head is determined at the widest part of the head and (C) is
then translated down to the level of the scapular axis for measurement
of subluxation. (D) Where there is higher-grade erosion with partial
humeral head collapse and osteophytes, measurement is more challenging.
Osteophytes (red arrow), whether on the humeral or glenoid side, must be
disregarded. The center of rotation is determined with the aid of the
intact outer margins of the humeral joint surface (blue stars).Method for determining the percentage of subluxation, s,
of the center of rotation of the humeral head from the scapular axis,
ax, relative to the radius, r,
using the given formula.Both observers measured all CT scans independently. Where large differences in
measurements (>10%) occurred, the cases were reassessed together until a
consensus was reached.Finally, reconstructed coronal, cross-sectional, and sagittal CT planes were
assessed to classify glenoid erosion (the third dimension). This was done
according to a grading system which was based on previous studies and adapted
for the 3D concept.
According to our descriptive observations, erosion was categorized into 3
types: grade 1, no significant bony erosion; grade 2, erosion causing a
biconcavity if eccentric or a central crater; and grade 3, neoglenoid covering
the entire glenoid surface in a single plane (or severe central erosion
including the glenoid rim) (Figure 4). All shoulders were graded accordingly, and the grade of
erosion was combined with the alignment type to complete the 3D
classification.
Figure 4.
Diagrammatic representation of the 3-dimensional classification for
degenerative arthritis of the shoulder. The humeroscapular alignment was
described in terms of subluxation of the center of rotation of the
humeral head in the anteroposterior direction (posterior [P]/central
[C]/anterior [A]) and the superoinferior direction (superior [S]/central
[C]/inferior [I]), for a total of 9 different combinations. Erosion was
graded from 1 to 3, where 1 = no significant bony erosion, 2 = focal
erosion forming a crater or biconcavity of the glenoid (in any
location), and 3 = severe glenoid erosion involving the entire glenoid
surface in any single plane (central or eccentric).
Diagrammatic representation of the 3-dimensional classification for
degenerative arthritis of the shoulder. The humeroscapular alignment was
described in terms of subluxation of the center of rotation of the
humeral head in the anteroposterior direction (posterior [P]/central
[C]/anterior [A]) and the superoinferior direction (superior [S]/central
[C]/inferior [I]), for a total of 9 different combinations. Erosion was
graded from 1 to 3, where 1 = no significant bony erosion, 2 = focal
erosion forming a crater or biconcavity of the glenoid (in any
location), and 3 = severe glenoid erosion involving the entire glenoid
surface in any single plane (central or eccentric).
Statistical Analysis
The statistical analysis was performed using SPSS Version 26.0 (IBM Corp)
software. The intraclass correlation coefficient (ICC) was used to measure
reproducibility of the measurements between the 2 observers. Normal distribution
was confirmed using the Shapiro-Wilk test. The Student t test
was used to measure the significance of differences in normally distributed data
sets, with the significance level set at P = .05. Values for
measurements were rounded to 1 decimal place, and values for standard deviation
as well as the ICC to 3 decimal places. As all available CT scans matching the
inclusion criteria were included, a power analysis was not performed.
Results
The results of DAS classification of the 130 shoulders according to the coronal
(modified Walch
) and cross-sectional (Hamada
and Favard
) planes frequently suggested a biplanar eccentricity (Table 2), which none of the existing
classification systems were able to comprehensively describe.
Table 2
DAS Classified According to the Cross-Sectional (Modified Walch
) Versus Coronal (Hamada
and Favard
) Planes (N = 130 Shoulders)
Modified Walch1
A1
A2
B1
B2
B3
C
D
Hamada8
1
2
12
4
11
10
0
3
2
11
3
4
4
4
0
1
3
10
2
7
1
1
0
2
4a
4
4
10
1
0
0
3
4b
0
2
2
7
3
0
1
5
0
0
0
0
0
0
1
Favard4
E0
15
0
5
2
0
0
3
E1
9
20
18
12
13
0
5
E2
3
1
4
7
2
0
2
E3
0
1
0
1
2
0
1
E4
0
1
0
2
1
0
0
Data are reported as number of shoulders. DAS, degenerative
arthritis of the shoulder.
DAS Classified According to the Cross-Sectional (Modified Walch
) Versus Coronal (Hamada
and Favard
) Planes (N = 130 Shoulders)Data are reported as number of shoulders. DAS, degenerative
arthritis of the shoulder.The mean diameter of the humeral head was 44.4 ± 4.05 mm (range, 36.1-55.8 mm) in the
cross-sectional plane and 47.0 ± 4.02 mm (range, 36.5-56.2 mm) in the coronal plane
of the reconstructed CT scans. A paired t test showed a significant
difference between these values (P < .001), confirming an
elliptical shape of the humeral head. The ICC values indicated a high degree of
intrarater reproducibility for all measured variables: humeral head diameter
(cross-sectional, 0.988; coronal, 0.981), A-P subluxation (0.901), and S-I
subluxation (0.971).
Humeroscapular Alignment
In the A-P plane, the HSA ranged from 74.1% posterior to 23.5% anterior (SD,
19.3%) when expressed relative to the radius of the humeral head (absolute
values, 16.9 mm posterior to 5.2 mm anterior). These values were then plotted
graphically in ascending order (Figure 5). With the aid of this graph,
as well as the impression gained while performing the measurements, HSA in the
A-P plane was classified into 3 types: anterior (>5% anterior subluxation),
central (between 5% anterior and 20% posterior subluxation), and posterior
(>20% posterior subluxation). A posterior shift of the range for central
alignment was supported by both the graphical analysis and our subjective
impression and is probably due to the physiological retroversion of the glenoid.
A further subtype (referred to as extraposterior) for particularly severe
posterior subluxation was defined for those with >60% posterior subluxation,
which corresponded to a notable step in the graph (see Figure 5, green arrow).
Figure 5.
Values for anteroposterior subluxation plotted in ascending order;
negative values indicate posterior subluxation. The red arrow marks the
step from central to anterior alignment, the green arrow the step from
posterior to extraposterior, and the yellow arrow the turning point of
increasing posterior subluxation, seen around –20%, which was taken as
the defining value between central and posterior alignment.
Values for anteroposterior subluxation plotted in ascending order;
negative values indicate posterior subluxation. The red arrow marks the
step from central to anterior alignment, the green arrow the step from
posterior to extraposterior, and the yellow arrow the turning point of
increasing posterior subluxation, seen around –20%, which was taken as
the defining value between central and posterior alignment.In the S-I plane, subluxation ranged from 17.2% inferior to 68.6% superior (SD,
17.1%) relative to the radius of the humeral head (absolute values, 4 mm
inferior to 16.8 mm superior). These values were also plotted graphically in
ascending order (Figure
6) and were classified into 3 types: superior (>20% superior
subluxation), central (between 5% inferior and 20% superior subluxation), and
inferior (>5% inferior subluxation). A superior shift of the range for
central alignment was again supported by both the graphical analysis and our
subjective impression and is probably due to the physiological inclination of
the glenoid as well as the tension of the deltoid muscle. Additionally, a
further subtype for those with extreme superior subluxation (referred to as
extrasuperior) was defined for those with static acetabularization. All patients
with >50% of superior subluxation (a notable step in the Figure 6 graph) were included in this
subtype. Other cases with established acetabularization but <50% subluxation
were unable to shift further superiorly because of the bony obstruction, which
is why the absolute value of subluxation was not taken as the cutoff for this
group.
Figure 6.
Values for superoinferior subluxation plotted in ascending order;
negative values indicate inferior subluxation. The red arrow marks the
step from central to inferior alignment, and the yellow arrow identifies
the turning point of increasing superior subluxation, seen at around
20%, which was taken as the defining value between central and superior
alignment.
Values for superoinferior subluxation plotted in ascending order;
negative values indicate inferior subluxation. The red arrow marks the
step from central to inferior alignment, and the yellow arrow identifies
the turning point of increasing superior subluxation, seen at around
20%, which was taken as the defining value between central and superior
alignment.Using these values to categorize the HSA, the 130 shoulders were classified into
the 9 possible combinations, as seen in Table 3. Only 21 shoulders were found
to be centered in both planes. Biplanar eccentricity was found in 25 patients
with posterosuperior, 5 patients with posteroinferior, and 4 patients with
anterosuperior alignment (34/130; 26%).
Table 3
Frequency of Cases According to the Categorization System of HSA
Posterior
Central
Anterior
Superior
25 (1 XP, 6 XS)
40 (9 XS)
4 (2 XS)
Central
31 (3 XP)
21
3
Inferior
5
1
0
Data in parentheses indicate the number of shoulders
additionally defined as having extraposterior (XP) or extrasuperior
(XS) alignment. HSA, humeroscapular alignment.
Frequency of Cases According to the Categorization System of HSAData in parentheses indicate the number of shoulders
additionally defined as having extraposterior (XP) or extrasuperior
(XS) alignment. HSA, humeroscapular alignment.The mean % A-P and S-I subluxation values for each alignment type can be found in
Table 4. There
was a significant difference in patients with anterior versus central versus
posterior A-P subluxation (P < .001; Student's
t test), as well as in patients with superior versus
central versus inferior S-I subluxation (P < .001; Student's
t test).
Table 4
A-P and S-I Subluxation for Each Alignment Type
Posterior, %
Central, %
Anterior, %
Superior
A-P subluxation: –31.7 ± 12.8 (–20.5 to –70.4)S-I
subluxation: 36.1 ± 13.2 (20.2 to 68.6)
A-P subluxation: –9.6 ± 7.70 (–19.8 to 4.8)S-I
subluxation: 32.0 ± 9.39 (20.1 to 60.1)
A-P subluxation: 16.8 ± 6.10 (9.1 to 23.5)S-I
subluxation: 45.6 ± 13.6 (29.0 to 62.0)
Central
A-P subluxation: –37.4 ± 16.1 (–20.3 to –74.1)S-I
subluxation: 7.5 ± 7.12 (–4.3 to 18.8)
A-P subluxation: –7.5 ± 7.88 (–19.9 to 4.5)S-I
subluxation: 12.3 ± 5.17 (0.9 to 19.5)
A-P subluxation: 17.7 ± 6.40 (10.5 to 22.6)S-I
subluxation: 9.8 ± 5.57 (3.8 to 14.9)
Inferior
A-P subluxation: –37.6 ± 13.7 (–25.1 to –58.3)S-I
subluxation: –12.6 ± 3.33 (–9.3 to –17.2)
A-P subluxation: –10.6S-I subluxation: –14.4
—
Data are reported as mean ± SD (range). Negative values
indicate posterior (anteroposterior [A-P] direction) or inferior
(superoinferior [S-I] direction) subluxation. The values are ranges
of subluxation in each group of the classification, expressed in %.
Dashes indicate none.
A-P and S-I Subluxation for Each Alignment TypeData are reported as mean ± SD (range). Negative values
indicate posterior (anteroposterior [A-P] direction) or inferior
(superoinferior [S-I] direction) subluxation. The values are ranges
of subluxation in each group of the classification, expressed in %.
Dashes indicate none.
Glenoid Erosion
The frequency of the various glenoid erosion grades according to HSA alignment
type is shown in Table
5. Figure 7
shows examples of grade 2 erosion, and Figure 8 shows an example of grade 3
erosion.
Table 5
Frequency of Cases According to HSA Type and Erosion Grade
Posterior
Central
Anterior
Superior
Grade 1
7
20
1
Grade 2
16
15
3
Grade 3
2
5
Central
Grade 1
5
4
Grade 2
11
13
3
Grade 3
15
4
Inferior
Grade 1
Grade 2
3
1
Grade 3
2
HSA, humeroscapular alignment. Blank cells indicate no
cases.
Figure 7.
An example of grade 2 central-central erosion shown on computed
tomography: (A) coronal, (B) cross-sectional, and (C) sagittal planes.
There is medialization of the humeral head, and it bisects a line
(dashed red line) drawn between the anterior and posterior and/or
superior and inferior glenoid rim, as described previously.
(D) An example of grade 2 erosion with a central crater but
without involvement of the entire glenoid surface.
Figure 8.
An example of grade 3 central-central erosion shown on computed
tomography: (A) coronal and (B) cross-sectional planes. The entire
glenoid surface, including the rim, is eroded and the humeral head is
embedded.
Frequency of Cases According to HSA Type and Erosion GradeHSA, humeroscapular alignment. Blank cells indicate no
cases.An example of grade 2 central-central erosion shown on computed
tomography: (A) coronal, (B) cross-sectional, and (C) sagittal planes.
There is medialization of the humeral head, and it bisects a line
(dashed red line) drawn between the anterior and posterior and/or
superior and inferior glenoid rim, as described previously.
(D) An example of grade 2 erosion with a central crater but
without involvement of the entire glenoid surface.An example of grade 3 central-central erosion shown on computed
tomography: (A) coronal and (B) cross-sectional planes. The entire
glenoid surface, including the rim, is eroded and the humeral head is
embedded.
Discussion
The findings of this study can be applied to quantify and categorize alignment of
DAS. This will modernize and combine the findings of previous seminal studies that
have classified arthritis of the shoulder.
Much of how previous classifications described glenoid erosion has been
incorporated into this classification
and adapted for the 3D concept according to our descriptive observations. New
to this classification is that the eccentricity is quantified in both the A-P and
the S-I planes and combined with the associated glenoid wear in 3 dimensions. This
seems to be important, as our study shows that a biplanar eccentricity is common,
representing 26% of this cohort. Overall, we accept our hypothesis that biplanar
eccentricity is common and alignment can be categorized into 9 sectors, of which we
have found cases in 8. This suggests that to comprehensively describe DAS, a 3D
classification such as the one outlined in this work should be used.Our findings align with a recent study that reported posterior glenoid erosion to be
present superiorly, centrally, and inferiorly.
Terrier et al
also found glenoid erosion to be present in all 3 posterior sectors, as well
as anteriorly, but predominantly posterosuperiorly. Jacxsens et al,
who assessed HSA in patients with Walch type B1 arthritis and averaged the
values between all patients, showed a predominance of the combination of posterior
with inferior subluxation of the humeral head. The results from our cohort, in which
each patient was assessed individually, are more in line with those of Terrier et al
than those of Jacxsens et al.
This difference is likely to be in part due to the inclusion of not only OA
but both types of DAS (CTA and OA) in our cohort.In our classification, the grading of glenoid erosion has been adapted from the Walch
and Favard systems and modified according to our descriptive observations for the 3D concept.
In contrast to this, the Lévigne classification of glenoid erosion, which was
developed using A-P radiographs of patients with rheumatoid arthritis, categorizes
the extent of erosion with reference to the coracoid process.
We did not incorporate this into our classification, because while it is
useful in describing the depth of erosion on A-P radiographs, it does not describe
the localization of erosion and does not transfer well to our 3D CT
classification.The extraposterior alignment type described in this classification (>60% posterior
subluxation relative to the radius of the humeral head) corresponds to the cutoff,
80% humeral head subluxation relative to the diameter, for implanting an anatomical
prosthesis suggested by Walch et al.Interestingly, not all patients diagnosed with CTA in our cohort had superior
subluxation (69 cases with superior alignment, 78 cases of CTA, 8 cases labeled as
OA with superior subluxation). It may be that these were cases with early disease
(Hamada grade 1), but it is also possible that in some cases the subluxation was
greater in the A-P plane after reconstruction. For example, a posterosuperior defect
with intact subscapularis may cause little static superior but significant posterior
subluxation, still reducing the distance to the acromion that lies posteriorly. This
will require further investigation. Of cases with superior subluxation with a
diagnosis of OA, 4 had posterosuperior and 4 centrosuperior alignment. This is an
important finding and underlines the need to analyze DAS in both planes.The underlying pathology leading to eccentric glenohumeral arthritis, which is
described by our classification, has been investigated to some extent. While direct
causality has not been clearly proven, it has been shown that posterior subluxation,
preceded by degeneration of the posterior rotator cuff (RC), precedes the
development of cartilaginous wear and glenoid erosion in Walch type B cases.
Increased retroversion/anteversion has also been described as a possible
influencing factor.
Whereas fatty infiltration of the subscapularis muscle leads to arthritis
with anterior subluxation,
progression of OA can lead to degeneration of all muscles of the RC,
culminating in fatty infiltration and dysfunction.
Although not yet fully understood, it can be said that to some extent
eccentric OA of the glenohumeral joint is, akin to CTA, a disease associated with RC
insufficiency. Furthermore, initially centered disease may later become eccentric.
As the disease progresses, the RC tendons may degenerate and tear, resulting
in a mixed pathology (ie, both OA and CTA). It therefore seems reasonable to
describe these diseases in 1 combined classification.The results of arthroplasty for cases with posterior subluxation are inconsistent.
Causes for this may include differences in the surgical procedure. However,
this may also in part be because the extent of the disease, possibly of a
bidirectional nature, is not fully understood by the surgeon preoperatively.
Outcomes of cases with biplanar eccentricity may not be comparable to those with
unidirectional subluxation, and specific treatment strategies may need to be
developed. These may include the use of augmented glenoid components or bone
grafting for eccentric erosion. Importantly, cases of OA with superior subluxation
may not be suitable for anatomical shoulder replacement and instead require a
semiconstrained reverse shoulder arthroplasty. Further studies will be required to
determine the clinical significance of this classification.The 3D reconstruction of the scapular axis has been shown to have a significant
effect on measurements of HSA, with which we concur in our own experience.
We therefore recommend the use of an image-viewing program that allows a
reconstruction of the scapular plane in 3 dimensions when assessing CT scans with
this classification. While humeroglenoid alignment is more reproducibly measured
than HSA, with and without 3D reconstruction of the scapular plane, this cannot be
used to sensitively describe malalignment, as increased/decreased retroversion or
inclination will lead to a falsely central measurement of the alignment.
Limitations
One point of criticism that may be made regarding our work is that S-I alignment
is usually not assessed in the lying patient on CT scans but rather on the
standing radiographs, according to known refence values regarding the
acromiohumeral interval.
However, we propose that the CT scan with a resting arm, without the
interference of gravity, will show an insufficiency of the rotator cuff more
sensitively than a standing A-P radiograph. The supine position in CT may also
lead to differences in the alignment in the A-P plane when compared with
axillary view radiographs taken while standing. Nevertheless, as this is a
CT-based classification, all images are taken with the patient lying down,
making comparisons fair.The frequency of high-grade erosion and eccentricity in our cohort may not be
representative of patients who undergo joint replacement overall. This is likely
to be because, as a university hospital department, we are referred many
patients with severe disease. Furthermore, the lack of shoulders with an
anteroinferior alignment in our sample does not preclude the existence of these,
which may be present in other cohorts. Our study focused purely on patients with
OA and CTA. The spectrum of alignment may also differ if the use of the
classification is extended to other diagnoses (eg, to patients with arthritis of
instability, rheumatoid arthritis, and posttraumatic arthritis).While the ICC for the measurements showed a high grade of reproducibility, we do
not expect clinicians to spend as much time as we did for this in the clinical
setting. A validation study to confirm reproducibility of the classification
within and between clinicians is required in the future. Three-dimensional
reconstruction, however, is paramount, and therefore adequate software and
practice, as well as time, will be needed to do this reliably, which may limit
the use of this classification. Having said this, 3D planning software with
automated reconstruction protocols is becoming more widely used, which will
simplify the application of this classification. The clinical significance of
this classification is yet to be determined. However, the present publication
presents a method to analyze HSA and erosion in 3 dimensions using a 3D clinical
image–viewing software, which gives clinical transferability to much of the
knowledge gained by previous authors using complex modeling software.
Conclusion
This work has shown a high prevalence of biplanar eccentricity in DAS and has
suggested cutoff values for the boundaries of centered HSA in both planes. We
therefore suggest the use of a 3D classification, which applies the combined HSA as
well as glenoid erosion to comprehensively describe DAS. The clinical significance
of a classification like this has yet to be determined.
Authors: Kyle E Walker; Xavier C Simcock; Bong Jae Jun; Joseph P Iannotti; Eric T Ricchetti Journal: J Bone Joint Surg Am Date: 2018-01-03 Impact factor: 5.284