Literature DB >> 35976565

Long-acting injectable PLGA/PLA depots for leuprolide acetate: successful translation from bench to clinic.

Samer R Abulateefeh1.   

Abstract

The excellent properties of polyesters combined with their ease of synthesis and modification enabled their wide use in the pharmaceutical industry. This has been translated into the approval of several injectable depots for clinical use. Long-acting depots for leuprolide acetate were among the first and most successful examples including Lupron Depot® and ELIGARD®. Studying these products is of great interest for researchers in both industry and academia. This will undoubtedly pave the road for the development of new as well as generic long-acting depots for a variety of drugs.
© 2022. Controlled Release Society.

Entities:  

Keywords:  ELIGARD®; Implant; In situ gelling; Lupron Depot®; Lutrate® Depot; Microparticles

Year:  2022        PMID： 35976565     DOI： 10.1007/s13346-022-01228-0

Source DB:  PubMed          Journal:  Drug Deliv Transl Res        ISSN： 2190-393X            Impact factor:   5.671


  40 in total

Review 1.  Nanosizing for oral and parenteral drug delivery: a perspective on formulating poorly-water soluble compounds using wet media milling technology.

Authors:  Elaine Merisko-Liversidge; Gary G Liversidge
Journal:  Adv Drug Deliv Rev       Date:  2011-01-09       Impact factor: 15.470

2.  Injectable, long-acting PLGA formulations: Analyzing PLGA and understanding microparticle formation.

Authors:  Kinam Park; Sarah Skidmore; Justin Hadar; John Garner; Haesun Park; Andrew Otte; Bong Kwan Soh; Gwangheum Yoon; Dijia Yu; Yeonhee Yun; Byung Kook Lee; Xiaohui Jiang; Yan Wang
Journal:  J Control Release       Date:  2019-05-06       Impact factor: 9.776

3.  The contribution of the in-vivo fate of an oil depot to drug absorption.

Authors:  R W Kalicharan; C Oussoren; P Schot; E de Rijk; H Vromans
Journal:  Int J Pharm       Date:  2017-06-17       Impact factor: 5.875

Review 4.  Clinically established biodegradable long acting injectables: An industry perspective.

Authors:  Christian Isalomboto Nkanga; Andreas Fisch; Mazda Rad-Malekshahi; Marieta Duvnjak Romic; Birgit Kittel; Thomas Ullrich; Jing Wang; Rui Werner Maçedo Krause; Sabine Adler; Twan Lammers; Wim E Hennink; Farshad Ramazani
Journal:  Adv Drug Deliv Rev       Date:  2020-11-14       Impact factor: 15.470

Review 5.  Quality by design thinking in the development of long-acting injectable PLGA/PLA-based microspheres for peptide and protein drug delivery.

Authors:  Chengqian Zhang; Liang Yang; Feng Wan; Hriday Bera; Dongmei Cun; Jukka Rantanen; Mingshi Yang
Journal:  Int J Pharm       Date:  2020-05-19       Impact factor: 5.875

Review 6.  Polyester based polymeric nano and microparticles for pharmaceutical purposes: A review on formulation approaches.

Authors:  Fatima Molavi; Mohammad Barzegar-Jalali; Hamed Hamishehkar
Journal:  J Control Release       Date:  2020-01-18       Impact factor: 9.776

7.  Tunable sustained release drug delivery system based on mononuclear aqueous core-polymer shell microcapsules.

Authors:  Samer R Abulateefeh; Mahmoud Y Alkawareek; Alaaldin M Alkilany
Journal:  Int J Pharm       Date:  2019-01-12       Impact factor: 5.875

8.  Pharmacokinetics and safety of subcutaneous pasireotide and intramuscular pasireotide long-acting release in Chinese male healthy volunteers: a phase I, single-center, open-label, randomized study.

Authors:  Xia Chen; Guoxiang Shen; Ji Jiang; Hongzhong Liu; Ke Hu; Christelle Darstein; Janet Lasher; Pei Hu
Journal:  Clin Ther       Date:  2014-07-08       Impact factor: 3.393

Review 9.  Injectable formulations of poly(lactic acid) and its copolymers in clinical use.

Authors:  Anjali Jain; Konda Reddy Kunduru; Arijit Basu; Boaz Mizrahi; Abraham J Domb; Wahid Khan
Journal:  Adv Drug Deliv Rev       Date:  2016-07-14       Impact factor: 15.470

Review 10.  Formulation composition, manufacturing process, and characterization of poly(lactide-co-glycolide) microparticles.

Authors:  Kinam Park; Andrew Otte; Farrokh Sharifi; John Garner; Sarah Skidmore; Haesun Park; Young Kuk Jhon; Bin Qin; Yan Wang
Journal:  J Control Release       Date:  2020-10-24       Impact factor: 11.467
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.