| Literature DB >> 27423636 |
Anjali Jain1, Konda Reddy Kunduru2, Arijit Basu2, Boaz Mizrahi3, Abraham J Domb4, Wahid Khan5.
Abstract
Poly(lactic acid) and its copolymers have revolutionized the field of drug delivery due to their excellent biocompatibility and tunable physico-chemical properties. These copolymers have served the healthcare sector by contributing many products to combat various diseases and for biomedical applications. This article provides a comprehensive overview of clinically used products of poly(lactic acid) and its copolymers. Multi-dimension information covering product approval, formulation aspects and clinical status is described to provide a panoramic overview of each product. Moreover, leading patented technologies and various clinical trials on these products for different applications are included. This review focuses on marketed injectable formulations of PLA and its copolymers.Entities:
Keywords: Injectable depot; Microspheres; PLA clinical products; PLA copolymers; Poly(lactic acid)
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Year: 2016 PMID： 27423636 DOI： 10.1016/j.addr.2016.07.002
Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470