| Literature DB >> 35954693 |
Vanessa Peynenburg1, Andreea Ababei1, Andrew Wilhelms1, Michael Edmonds1, Nick Titov2, Blake F Dear3, Viktor Kaldo4,5, Susanna Jernelöv4,6, Heather D Hadjistavropoulos1.
Abstract
Patients seeking transdiagnostic internet-delivered cognitive behavior therapy (T-ICBT) for anxiety or depression often have sleep difficulties. A brief resource that includes sleep psychoeducation and strategies for improving sleep (e.g., stimulus control and sleep restriction) may address comorbid insomnia without the need for an insomnia-specific ICBT course. This observational study explored patient use and feedback of a brief sleep resource available to all patients (n = 763) enrolled in an 8-week T-ICBT course. Overall, 30.1% of patients (n = 230) reviewed the resource and were older, more engaged with the ICBT course (i.e., more likely to complete the program, more logins, and greater number of days enrolled in the course) and had higher pretreatment insomnia symptoms than those who did not review the resource. Resource reviewers did not report larger improvements in symptoms of insomnia than non-reviewers, even among patients with clinical levels of insomnia, and average insomnia levels remained above the clinical cutoff at posttreatment. While patients were satisfied with the resource and it was beneficial to some patients, more research is needed to further explore how it may be integrated into T-ICBT and how therapists can encourage the use of the resource among patients who may benefit from the resource.Entities:
Keywords: insomnia; internet-delivered cognitive behavior therapy; transdiagnostic
Mesh:
Year: 2022 PMID: 35954693 PMCID: PMC9368049 DOI: 10.3390/ijerph19159337
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 4.614
Patient characteristics at pretreatment.
| Variable | All Patients | Accessed Good Sleep Resource (Reviewers) | Did Not Access Good Sleep Resource (Non-Reviewers) | Questionnaire Non-Responders (QNR) | Statistical Significance | ||||
|---|---|---|---|---|---|---|---|---|---|
|
| % |
| % |
| % |
| % | ||
| Age | |||||||||
| Mean (SD) | 37.67 (13.8) | - | 43.93 (15.28) | - | 35.68 (12.85) | - | 34.32 (12.07) | - | |
| Range | 18–84 | - | 18–81 | - | 18–84 | - | 18–77 | - | |
| Gender | |||||||||
| Female | 589 | 77.2 | 176 | 76.5 | 205 | 79.5 | 208 | 75.6 | χ2 (1, 763) = 0.04; |
| Male/Other | 174 | 22.8 | 54 | 23.5 | 53 | 20.5 | 67 | 24.4 | |
| Marital status | |||||||||
| Single/never married | 251 | 32.9 | 64 | 27.9 | 80 | 31.0 | 107 | 39.0 | χ2 (1, 763) = 7.36; |
| Married/common-law | 452 | 59.2 | 143 | 62.2 | 160 | 62.0 | 149 | 54.1 | |
| Separated/ | 60 | 7.9 | 23 | 10.0 | 18 | 7.0 | 19 | 6.9 | |
| Education | |||||||||
| High school or less | 163 | 21.4 | 50 | 21.7 | 44 | 17.1 | 69 | 25.1 | χ2 (1, 763) = 5.55; |
| More than high school/ less than university | 339 | 44.4 | 92 | 40.0 | 115 | 44.6 | 132 | 48.0 | |
| University education | 261 | 34.2 | 88 | 38.3 | 99 | 38.4 | 74 | 26.9 | |
| Employment status | |||||||||
| Employed part-time/full-time | 383 | 50.2 | 104 | 45.2 | 131 | 50.8 | 148 | 53.8 | χ2 (1, 763) = 6.25; |
| Unemployed/disability | 153 | 20.1 | 50 | 21.7 | 38 | 14.7 | 65 | 23.6 | |
| Homemaker/Student/ retired | 227 | 29.8 | 76 | 33.0 | 89 | 34.5 | 62 | 22.6 | |
| Ethnicity | |||||||||
| White | 661 | 86.6 | 211 | 91.7 | 223 | 86.4 | 227 | 82.5 | χ2 (1, 763) = 6.32; |
| Indigenous | 45 | 5.9 | 7 | 3.0 | 14 | 5.4 | 24 | 8.7 | |
| Other | 57 | 7.5 | 12 | 5.2 | 21 | 8.1 | 24 | 8.7 | |
| Location | |||||||||
| Large city (over 100,000) | 440 | 57.7 | 133 | 57.8 | 149 | 57.8 | 158 | 57.5 | χ2 (1, 763) = 0.28; |
| Small to medium city | 113 | 14.8 | 30 | 13.0 | 34 | 13.2 | 49 | 17.8 | |
| Small rural location (under 10,000) | 210 | 27.5 | 67 | 29.1 | 75 | 29.1 | 68 | 24.7 | |
| Pretreatment scores | |||||||||
| Insomnia Severity Index ≥10 | 522 | 72.3 | 183 | 79.6 | 156 | 60.5 | 213 | 77.5 | χ2 (1, 763) = 27.78; |
| Pretreatment PHQ-9 ≥ 10 | 559 | 73.3 | 174 | 75.7 | 164 | 63.6 | 221 | 80.4 | χ2 (1, 763) = 2.00; |
| Pretreatment GAD-7 ≥ 10 | 549 | 72.0 | 159 | 69.1 | 177 | 68.8 | 213 | 77.5 | χ2 (1, 763) = 4.61; |
| No clinical scores | 69 | 9.0 | 17 | 7.4 | 33 | 12.8 | 19 | 6.9 | χ2 (1, 763) = 6.69; |
| Psychotropic medication in the past 3 months | 419 | 54.9 | 127 | 55.2 | 127 | 49.2 | 165 | 60.0 | χ2 (1, 763) = 1.42; |
| Pretreatment credibility | 20.70 (4.54) | - | 20.70 (4.29) | - | 20.62 (4.55) | - | 20.77 (4.75) | - | |
Notes: PHQ-9 = Patient Health Questionnaire 9; GAD-7 = Generalized Anxiety Disorder 7.
Pretreatment and posttreatment symptom scores and change scores.
| Variable (Post | Combined | Accessed Good Sleep Resource | Did Not Access Good Sleep Resource (Non-Reviewers) | Statistical Significance | Statistical Significance | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre-Mean | Post-Mean | Change Score | Pre-Mean | Post-Mean | Change Score | Pre-Mean | Post-Mean | Change Score | |||
| ISI | 13.16 | 9.82 | −3.32 | 14.95 | 11.14 | −3.80 | 11.57 | 8.63 | −2.92 | ||
| PHQ-9 | 12.69 | 6.79 | −5.88 | 13.27 | 7.05 | −6.22 | 12.17 | 6.56 | −5.58 | ||
| GAD-7 | 12.09 | 6.18 | −5.89 | 12.24 | 6.03 | −6.21 | 11.96 | 6.32 | −5.61 | ||
| SDS | 17.41 | 13.79 | −3.62 | 17.67 | 14.36 | −3.31 | 17.19 | 13.29 | −3.90 | ||
Notes: ISI = Insomnia Severity Index; PHQ-9 = Patient Health Questionnaire 9; GAD-7 = Generalized Anxiety Disorder 7; SDS = Sheehan Disability Scale.
Effect sizes (Cohen’s d, 95% CI) for symptom changes from pretreatment to posttreatment.
| Variable | Overall Sample | Patients with Clinical Levels of Insomnia | ||
|---|---|---|---|---|
| Accessed Good Sleep Resource (Reviewers) | Did Not Access Good Sleep Resource (Non-Reviewers) | Accessed Good Sleep Resource | Did Not Access Good Sleep Resource (Non-Reviewers) | |
| Cohen’s d | Cohen’s d | Cohen’s d | Cohen’s | |
| ISI | 0.70 | 0.56 | 0.88 | 0.80 |
| PHQ-9 | 1.08 | 1.10 | 1.13 | 1.19 |
| GAD-7 | 1.14 | 1.13 | 1.17 | 1.14 |
| SDS | 0.41 | 0.51 | 0.43 | 0.49 |
Notes: ISI = Insomnia Severity Index; PHQ-9 = Patient Health Questionnaire 9; GAD-7 = Generalized Anxiety Disorder 7; SDS = Sheehan Disability Scale.
Treatment engagement and satisfaction.
| Variable | Combined | Accessed Good Sleep Resource (Reviewers) | Did Not Access Good Sleep Resource (Non-Reviewers) | Statistical Significance | |||
|---|---|---|---|---|---|---|---|
| ( | ( | ( | |||||
|
| % |
| % |
| % | ||
| Support | |||||||
| Optional 1x week | 285 | 58.4 | 134 | 58.2 | 151 | 58.5 | χ2 (1, 488) = 0.004; |
| Standard 1x week | 203 | 41.6 | 96 | 41.7 | 107 | 41.5 | |
| Engagement | |||||||
| Accessed lesson 4 | 459 | 94.1 | 222 | 96.5 | 237 | 91.9 | χ2 (1, 488) = 4.72; |
| Accessed lesson 5 | 428 | 87.7 | 214 | 93 | 214 | 82.9 | χ2 (1, 488) = 11.47; |
| Completion of 8-week primary measures | 487 | 99.8 | 230 | 100 | 257 | 99.6 | χ2 (1, 488) = 0.89; |
| Mean written messages received from therapist (SD) | 7.09 | - | 7.3 | - | 6.90 (2.66) | - | |
| −2.64 | −2.61 | ||||||
| Mean written messages sent to therapist (SD) | 3.46 | - | 3.79 | - | 3.17 (2.60) | - | |
| −3.02 | −3.39 | ||||||
| Mean number of logins (SD) | 26.65 | - | 29.67 (29.29) | - | 23.96 (13.45) | - | |
| −22.52 | |||||||
| Mean number of phone calls with therapist (SD) | - | 0.83 | - | 1.02 (1.40) | - | ||
| 0.93 | −1.17 | ||||||
| −1.3 | |||||||
| Mean days between first and last login (SD) | 81.81 | - | 85.90 (33.40) | - | 78.17 (21.38) | - | |
| −32.54 | |||||||
| Satisfaction | |||||||
| Satisfied/very satisfied overall | 397 | 81.4 | 185 | 80.4 | 212 | 82.2 | χ2 (1, 488) = 0.24; |
| Course was worth the time (%) | 470 | 96.3 | 222 | 96.5 | 248 | 96.1 | χ2 (1, 488) = 0.05; |
| Would recommend course to friend (%) | 469 | 96.1 | 221 | 96.1 | 248 | 96.1 | χ2 (1, 488) = 0.00; |
| Increased/greatly increased confidence | 409 | 83.8 | 189 | 82.2 | 220 | 85.3 | χ2 (1, 488) = 0.86; |
| Increased/greatly increased motivation for other treatment | 380 | 77.9 | 182 | 79.1 | 198 | 76.7 | χ2 (1, 488) = 0.40; |
Patient responses to the question, what did you like about the resource? (n = 230).
| Liked | Example | Patient ID |
| % |
|---|---|---|---|---|
| Overall information (positive feedback, everything, general tips for sleep) | “I liked how informative it was and quite relatable to be able to help some of my insomnia needs”. | 34048 | 87 | 37.8 |
| Sleep education (learning new things, reinforce, remind) | “It reminded me that healthy sleep is an important determinant of overall health and that I should focus on making my sleep healthy as well”. | 33995 | 84 | 36.5 |
| Sleep improvement strategies | “It gave me strategies to use to develop a good sleep routine/develop better sleep habits”. | 35000 | 56 | 24.3 |
| Sleep restriction | “It gave me a plan that WORKED to help me sleep. It gave me confidence to stay awake and wake up early to feel tired at night”. | 35198 | 16 | 7.0 |
| Stimulus control | “Had to learn that was not a place to hang out. It was for peace and sleep. No phone or movies”. | 33902 | 16 | 7.0 |
| Routine | “The advice about creating a healthy bedtime routine that starts with doing something relaxing in the evening before even going to bed”. | 33952 | 27 | 11.7 |
| Presentation (format, structure, layout, downloadable) | “Everything was well laid out and easy to understand”. | 34390 | 35 | 15.2 |
| Nothing/can’t remember (N/A, no response, not sure) | “Nothing stands out in my mind”. | 34256 | 28 | 12.1 |
| Content doesn’t apply (no issue sleeping) | “The information was there to use but I do not have a problem sleeping”. | 34772 | 8 | 3.5 |
Note: Responses could be coded more than once.
Patient responses to question, what did you not like about the resource? (n = 230).
| Disliked | Example | Patient ID |
| % |
|---|---|---|---|---|
| Nothing/ found all content helpful | “Everything was great about this course”. | 34769 | 111 | 48.3 |
| N/A, not sure, don’t remember, no response | “N/A”. | 33949 | 62 | 27.0 |
| No new information | “There wasn’t a lot of new information to me”. | 33947 | 30 | 13.0 |
| Not relevant to patient experiences (wanting additional information, unhelpful content) | “I was looking for more information on managing sleep when working night shifts. The resource touched on it minimally and I did not find it helpful”. | 34764 | 27 | 11.7 |
| Format issues | “My attention span for reading right now is not so good so I wished I could watch a video instead but I managed”. | 34560 | 3 | 1.3 |
Note: Responses could be coded more than once.
Patient responses to question, did you make any changes to how you manage sleep based on the Good Sleep Resource? (n = 230).
| Changes Made | Example | Patient ID |
| % |
|---|---|---|---|---|
| Yes | “Yes. I focus more on getting a good sleep”. | 34046 | 135 | 58.7 |
| Sleep restriction | “I used the sleep restriction strategy to set up a stricter sleep schedule. I would tend to stay up later than I should some nights, so I now make sure that I always go to bed at the same time”. | 35264 | 36 | 15.7 |
| Stimulus control | “Yes. Bedroom is now distraction free. No TV or technology”. | 34544 | 41 | 17.8 |
| Routine | “I started to try and exercise more, and ‘wind-down’ by trying to do more bedtime yoga stretches before bed, or reading a book to limit screen time. I also started practicing controlled breathing in bed to help me relax”. | 33866 | 85 | 37.0 |
| Work in progress/trying | “I’ve tried. Sleep is an ongoing battle, but I am working on heathy sleep habits”. | 33864 | 118 | 51.3 |
| No | “No changes”. | 34852 | 79 | 34.3 |
| I don’t know, N/A | “N/A”. | 33858 | 11 | 4.8 |
Note: Responses could be coded more than once.