STUDY OBJECTIVES: To compare treatment effects when patients with insomnia and depression receive treatment for either insomnia or depression. DESIGN: A 9-w randomized controlled trial with 6- and 12-mo follow-up. SETTING: Internet Psychiatry Clinic, Stockholm, Sweden. PARTICIPANTS: Forty-three adults in whom comorbid insomnia and depression were diagnosed, recruited via media and assessed by psychiatrists. INTERVENTIONS:Guided Internet-delivered cognitive behavior therapy (ICBT) for either insomnia or depression. MEASUREMENTS AND RESULTS: Primary outcome measures were symptom self-rating scales (Insomnia Severity Index [ISI] and the Montgomery Åsberg Depression Rating Scale [MADRS-S]), assessed before and after treatment with follow-up after 6 and 12 mo. The participants' use of sleep medication and need for further treatment after completion of ICBT was also investigated. The insomnia treatment was more effective than the depression treatment in reducing insomnia severity during treatment (P = 0.05), and equally effective in reducing depression severity. Group differences in insomnia severity were maintained during the 12-mo follow-up period. Post treatment, participants receiving treatment for insomnia had significantly less self-rated need for further insomnia treatment (P < 0.001) and used less sleep medication (P < 0.05) than participants receiving treatment for depression. The need for depression treatment was similar in both groups. CONCLUSIONS: In this study, Internet-delivered treatment with cognitive behavior therapy (ICBT) for insomnia was more effective than ICBT for depression for patients with both diagnoses. This indicates, in line with previous research, that insomnia when comorbid with depression is not merely a symptom of depression, but needs specific treatment. TRIAL REGISTRATION: The trial was registered at Clinicaltrials.gov, registration ID: NCT01256099.
RCT Entities:
STUDY OBJECTIVES: To compare treatment effects when patients with insomnia and depression receive treatment for either insomnia or depression. DESIGN: A 9-w randomized controlled trial with 6- and 12-mo follow-up. SETTING: Internet Psychiatry Clinic, Stockholm, Sweden. PARTICIPANTS: Forty-three adults in whom comorbid insomnia and depression were diagnosed, recruited via media and assessed by psychiatrists. INTERVENTIONS: Guided Internet-delivered cognitive behavior therapy (ICBT) for either insomnia or depression. MEASUREMENTS AND RESULTS: Primary outcome measures were symptom self-rating scales (Insomnia Severity Index [ISI] and the Montgomery Åsberg Depression Rating Scale [MADRS-S]), assessed before and after treatment with follow-up after 6 and 12 mo. The participants' use of sleep medication and need for further treatment after completion of ICBT was also investigated. The insomnia treatment was more effective than the depression treatment in reducing insomnia severity during treatment (P = 0.05), and equally effective in reducing depression severity. Group differences in insomnia severity were maintained during the 12-mo follow-up period. Post treatment, participants receiving treatment for insomnia had significantly less self-rated need for further insomnia treatment (P < 0.001) and used less sleep medication (P < 0.05) than participants receiving treatment for depression. The need for depression treatment was similar in both groups. CONCLUSIONS: In this study, Internet-delivered treatment with cognitive behavior therapy (ICBT) for insomnia was more effective than ICBT for depression for patients with both diagnoses. This indicates, in line with previous research, that insomnia when comorbid with depression is not merely a symptom of depression, but needs specific treatment. TRIAL REGISTRATION: The trial was registered at Clinicaltrials.gov, registration ID: NCT01256099.
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