| Literature DB >> 3586856 |
Abstract
To determine why animals reject alcohol when offered palatable solutions of sucrose, male C57BL/6J mice were challenged first with 5% sucrose then with 10% sucrose, while given continuous free-access to alcohol and water. The 5% sucrose dramatically reduced the intake of alcohol and increased the intake of total fluid by an average of 7.3 ml/day. The suppression of alcohol intake could not be attributed to a volumetric ceiling since access to 10% sucrose produced a further large increase in total intake (8.8 ml/day). The results support the interpretation that animals consume alcohol for characteristics it shares with sucrose.Entities:
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Year: 1987 PMID: 3586856 DOI: 10.1016/0024-3205(87)90010-5
Source DB: PubMed Journal: Life Sci ISSN: 0024-3205 Impact factor: 5.037