Literature DB >> 3586856

Why does a sucrose choice reduce the consumption of alcohol in C57BL/6J mice?

R T Gentry, V P Dole.   

Abstract

To determine why animals reject alcohol when offered palatable solutions of sucrose, male C57BL/6J mice were challenged first with 5% sucrose then with 10% sucrose, while given continuous free-access to alcohol and water. The 5% sucrose dramatically reduced the intake of alcohol and increased the intake of total fluid by an average of 7.3 ml/day. The suppression of alcohol intake could not be attributed to a volumetric ceiling since access to 10% sucrose produced a further large increase in total intake (8.8 ml/day). The results support the interpretation that animals consume alcohol for characteristics it shares with sucrose.

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Year:  1987        PMID: 3586856     DOI: 10.1016/0024-3205(87)90010-5

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  10 in total

1.  A concurrently available nondrug reinforcer prevents the acquisition or decreases the maintenance of cocaine-reinforced behavior.

Authors:  M E Carroll; S T Lac; S L Nygaard
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

2.  Intake of ethanol, sodium chloride, sucrose, citric acid, and quinine hydrochloride solutions by mice: a genetic analysis.

Authors:  A A Bachmanov; D R Reed; M G Tordoff; R A Price; G K Beauchamp
Journal:  Behav Genet       Date:  1996-11       Impact factor: 2.805

3.  Influence of the number of alcohol and water bottles on murine alcohol intake.

Authors:  M G Tordoff; A A Bachmanov
Journal:  Alcohol Clin Exp Res       Date:  2003-04       Impact factor: 3.455

4.  Chemosensory factors influencing alcohol perception, preferences, and consumption.

Authors:  Alexander A Bachmanov; Stephen W Kiefer; Juan Carlos Molina; Michael G Tordoff; Valerie B Duffy; Linda M Bartoshuk; Julie A Mennella
Journal:  Alcohol Clin Exp Res       Date:  2003-02       Impact factor: 3.455

5.  Voluntary consumption of ethanol in 15 inbred mouse strains.

Authors:  J K Belknap; J C Crabbe; E R Young
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

6.  Genetical genomic determinants of alcohol consumption in rats and humans.

Authors:  Boris Tabakoff; Laura Saba; Morton Printz; Pam Flodman; Colin Hodgkinson; David Goldman; George Koob; Heather N Richardson; Katerina Kechris; Richard L Bell; Norbert Hübner; Matthias Heinig; Michal Pravenec; Jonathan Mangion; Lucie Legault; Maurice Dongier; Katherine M Conigrave; John B Whitfield; John Saunders; Bridget Grant; Paula L Hoffman
Journal:  BMC Biol       Date:  2009-10-27       Impact factor: 7.431

7.  Toward an analogue of alcoholism in mice: analysis of nongenetic variance in consumption of alcohol.

Authors:  V P Dole; A Ho; R T Gentry; A Chin
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

8.  Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward.

Authors:  Sophie Laguesse; Nadege Morisot; Jung Hoon Shin; Feng Liu; Martin F Adrover; Samuel A Sakhai; Marcelo F Lopez; Khanhky Phamluong; William C Griffin; Howard C Becker; Kevin J Bender; Veronica A Alvarez; Dorit Ron
Journal:  Neuron       Date:  2017-09-08       Impact factor: 17.173

9.  Ethanol consumption and taste preferences in C57BL/6ByJ and 129/J mice.

Authors:  A A Bachmanov; M G Tordoff; G K Beauchamp
Journal:  Alcohol Clin Exp Res       Date:  1996-04       Impact factor: 3.455

Review 10.  Behavioral genetics and taste.

Authors:  John D Boughter; Alexander A Bachmanov
Journal:  BMC Neurosci       Date:  2007-09-18       Impact factor: 3.288

  10 in total

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