Literature DB >> 35835573

Modifiable Patient Factors Demonstrate No Increased Risk for 30-Day Complication Rate for Elective 1-2 Level Posterior Lumbar Fusion Surgery: A Comparison Between a National Database and Local Registry.

Cameron Kia1, Aris Yannopoulos2,3, Sagar Gulati4, Michael Cremins3, Mark Cote4, Isaac Moss4.   

Abstract

BACKGROUND: While national databases provide large datasets that can be used to understand trends over time, their correlation with prospectively collected data from local registries has not been established. The purpose of the study was to compare differences in patient demographics and adverse events for patients undergoing elective posterior spinal fusion (PSF) between a national database and institutional registry.
METHODS: A retrospective chart review was performed. A total of 14,618 patients (13,678 patients from the National Surgical Quality Improvement Program [NSQIP] database and 940 patients from the institutional registry) who underwent elective 1- to 2-level PSF were included in the study. Preoperative patient demographics and comorbidities of each cohort were compared. In addition, postoperative 30-day complications and readmission were collected. A multivariate analysis was performed to examine for differences in risk factors for 30-day adverse events between the 2 cohorts.
RESULTS: A total of 13,678 patients from the NSQIP database and 940 patients from the institutional cohort were included for analysis. Mean age was similar between patient cohorts (60.8 ± 13.1NSQIP vs 58.8 ± 12.9registry), with NSQIP having significantly more patients over the age of 65 (41.4% vs 33.2%, P < 0.001). Overall complication rate was similar between NSQIP (6.8%) and the institutional registry (8.4%). Both found age and female sex to be significant predictors of 30-day adverse events, while obesity, hypertension, and smoking were only found to be predictive in the NSQIP database.
CONCLUSIONS: Age and female sex were found to be independent risk factors for 30-day adverse events between both cohorts, while only NSQIP found modifiable comorbidities to be significant predictors. Although large databases allow for trends in quality over time, subtleties in practice variation and data collection methods at the individual institution level need to be considered when generalizing findings, especially as it pertains to modifiable factors. CLINICAL RELEVANCE: Quality metrics and risk factors for patient outcomes are often derived from national databases. This study highlights the differences between study results when outcomes are derived from an institutional registry compared to a national database. This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery.
Copyright © 2022 ISASS. To see more or order reprints or permissions, see http://ijssurgery.com.

Entities:  

Keywords:  NSQIP; adult; adverse events; clinical outcomes; database outcomes; fusion; institutional registry; lumbar; posterior spinal fusion

Year:  2022        PMID: 35835573      PMCID: PMC9421259          DOI: 10.14444/8296

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  16 in total

Review 1.  Posterior lumbar interbody fusion.

Authors:  Christian P DiPaola; Robert W Molinari
Journal:  J Am Acad Orthop Surg       Date:  2008-03       Impact factor: 3.020

2.  Risk of infection following posterior instrumented lumbar fusion for degenerative spine disease in 817 consecutive cases.

Authors:  Kaisorn L Chaichana; Mohamad Bydon; David R Santiago-Dieppa; Lee Hwang; Gregory McLoughlin; Daniel M Sciubba; Jean-Paul Wolinsky; Ali Bydon; Ziya L Gokaslan; Timothy Witham
Journal:  J Neurosurg Spine       Date:  2013-11-08

3.  Spinal fusion in the United States: analysis of trends from 1998 to 2008.

Authors:  Sean S Rajaee; Hyun W Bae; Linda E A Kanim; Rick B Delamarter
Journal:  Spine (Phila Pa 1976)       Date:  2012-01-01       Impact factor: 3.468

4.  Variations in data collection methods between national databases affect study results: a comparison of the nationwide inpatient sample and national surgical quality improvement program databases for lumbar spine fusion procedures.

Authors:  Daniel D Bohl; Glenn S Russo; Bryce A Basques; Nicholas S Golinvaux; Michael C Fu; William D Long; Jonathan N Grauer
Journal:  J Bone Joint Surg Am       Date:  2014-12-03       Impact factor: 5.284

Review 5.  Surgical research using national databases.

Authors:  Ram K Alluri; Hyuma Leland; Nathanael Heckmann
Journal:  Ann Transl Med       Date:  2016-10

6.  Approach-based Comparative and Predictor Analysis of 30-day Readmission, Reoperation, and Morbidity in Patients Undergoing Lumbar Interbody Fusion Using the ACS-NSQIP Dataset.

Authors:  Austen David Katz; Nickolas Mancini; Teja Karukonda; Matthew Greenwood; Mark Cote; Isaac L Moss
Journal:  Spine (Phila Pa 1976)       Date:  2019-03-15       Impact factor: 3.468

7.  Risk factors and pharmacologic prophylaxis for venous thromboembolism in elective spine surgery.

Authors:  Ryan P McLynn; Pablo J Diaz-Collado; Taylor D Ottesen; Nathaniel T Ondeck; Jonathan J Cui; Patawut Bovonratwet; Blake N Shultz; Jonathan N Grauer
Journal:  Spine J       Date:  2017-10-19       Impact factor: 4.166

Review 8.  Database and Registry Research in Orthopaedic Surgery: Part 2: Clinical Registry Data.

Authors:  Andrew J Pugely; Christopher T Martin; Jared Harwood; Kevin L Ong; Kevin J Bozic; John J Callaghan
Journal:  J Bone Joint Surg Am       Date:  2015-11-04       Impact factor: 5.284

9.  Increased Utilization of American Administrative Databases and Large-scale Clinical Registries in Orthopaedic Research, 1996 to 2016.

Authors:  Nicholas W Karlson; Teron A Nezwek; Mariano E Menendez; David Tybor; Matthew J Salzler
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2018-11-16

Review 10.  Current status of adult spinal deformity.

Authors:  J A Youssef; D O Orndorff; C A Patty; M A Scott; H L Price; L F Hamlin; T L Williams; J S Uribe; V Deviren
Journal:  Global Spine J       Date:  2012-10-05
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