| Literature DB >> 3582483 |
M Garty, D Scolnik, Y Danziger, B Volovitz, D N Ilfeld, I Varsano.
Abstract
Six asthmatic children participated in an acute crossover randomized study. They received a single dose of aminophylline syrup 6 mg/kg after having received ketotifen syrup 1 mg b.i.d. or placebo for 8 days. Ketotifen did not significantly affect the heart rate, pulse pressure or such pharmacokinetic parameters of theophylline as peak serum level, time to peak, half life and AUC. Thus, ketotifen had no significant effect on the disposition of theophylline.Entities:
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Year: 1987 PMID： 3582483 DOI： 10.1007/bf00542193
Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953