Literature DB >> 35815095

An alert tool to promote lung protective ventilation for possible acute respiratory distress syndrome.

Andrew J Knighton1, Kathryn G Kuttler2, Pallavi Ranade-Kharkar2, Lauren Allen1, Taylor Throne1, Jason R Jacobs3, Lori Carpenter3, Carrie Winberg3, Kyle Johnson2, Neer Shrestha2, Jeffrey P Ferraro4, Doug Wolfe1, Ithan D Peltan3, Rajendu Srivastava1, Colin K Grissom3.   

Abstract

Objective: Computer-aided decision tools may speed recognition of acute respiratory distress syndrome (ARDS) and promote consistent, timely treatment using lung-protective ventilation (LPV). This study evaluated implementation and service (process) outcomes with deployment and use of a clinical decision support (CDS) synchronous alert tool associated with existing computerized ventilator protocols and targeted patients with possible ARDS not receiving LPV. Materials and
Methods: We performed an explanatory mixed methods study from December 2019 to November 2020 to evaluate CDS alert implementation outcomes across 13 intensive care units (ICU) in an integrated healthcare system with >4000 mechanically ventilated patients annually. We utilized quantitative methods to measure service outcomes including CDS alert tool utilization, accuracy, and implementation effectiveness. Attitudes regarding the appropriateness and acceptability of the CDS tool were assessed via an electronic field survey of physicians and advanced practice providers.
Results: Thirty-eight percent of study encounters had at least one episode of LPV nonadherence. Addition of LPV treatment detection logic prevented an estimated 1812 alert messages (41%) over use of disease detection logic alone. Forty-eight percent of alert recommendations were implemented within 2 h. Alert accuracy was estimated at 63% when compared to gold standard ARDS adjudication, with sensitivity of 85% and positive predictive value of 62%. Fifty-seven percent of survey respondents observed one or more benefits associated with the alert.
Conclusion: Introduction of a CDS alert tool based upon ARDS risk factors and integrated with computerized ventilator protocol instructions increased visibility to gaps in LPV use and promoted increased adherence to LPV.
© The Author(s) 2022. Published by Oxford University Press on behalf of the American Medical Informatics Association.

Entities:  

Keywords:  acute lung injury; acute respiratory distress syndrome; clinical decision support systems; computerized ventilation protocols; lung protective ventilation

Year:  2022        PMID: 35815095      PMCID: PMC9263532          DOI: 10.1093/jamiaopen/ooac050

Source DB:  PubMed          Journal:  JAMIA Open        ISSN: 2574-2531


  46 in total

1.  Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.

Authors:  Giacomo Bellani; John G Laffey; Tài Pham; Eddy Fan; Laurent Brochard; Andres Esteban; Luciano Gattinoni; Frank van Haren; Anders Larsson; Daniel F McAuley; Marco Ranieri; Gordon Rubenfeld; B Taylor Thompson; Hermann Wrigge; Arthur S Slutsky; Antonio Pesenti
Journal:  JAMA       Date:  2016-02-23       Impact factor: 56.272

2.  A Critical Care Clinician Survey Comparing Attitudes and Perceived Barriers to Low Tidal Volume Ventilation with Actual Practice.

Authors:  Curtis H Weiss; David W Baker; Katrina Tulas; Shayna Weiner; Meagan Bechel; Alfred Rademaker; Angela Fought; Richard G Wunderink; Stephen D Persell
Journal:  Ann Am Thorac Soc       Date:  2017-11

Review 3.  Acute Respiratory Distress Syndrome.

Authors:  B Taylor Thompson; Rachel C Chambers; Kathleen D Liu
Journal:  N Engl J Med       Date:  2017-08-10       Impact factor: 91.245

4.  Acute respiratory distress syndrome: underrecognition by clinicians.

Authors:  Stephen Fröhlich; Noelle Murphy; Aoife Doolan; Orla Ryan; John Boylan
Journal:  J Crit Care       Date:  2013-06-24       Impact factor: 3.425

Review 5.  Computerized clinical decision support for medication prescribing and utilization in pediatrics.

Authors:  Jeremy S Stultz; Milap C Nahata
Journal:  J Am Med Inform Assoc       Date:  2012-07-19       Impact factor: 4.497

6.  Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study.

Authors:  Erick H Duan; Neill K J Adhikari; Frederick D'Aragon; Deborah J Cook; Sangeeta Mehta; Waleed Alhazzani; Ewan Goligher; Emmanuel Charbonney; Yaseen M Arabi; Tim Karachi; Alexis F Turgeon; Lori Hand; Qi Zhou; Peggy Austin; Jan Friedrich; Francois Lamontagne; François Lauzier; Rakesh Patel; John Muscedere; Richard Hall; Pierre Aslanian; Thomas Piraino; Martin Albert; Sean M Bagshaw; Mike Jacka; Gordon Wood; William Henderson; Delbert Dorscheid; Niall D Ferguson; Maureen O Meade
Journal:  Ann Am Thorac Soc       Date:  2017-12

7.  Improving recognition of drug interactions: benefits and barriers to using automated drug alerts.

Authors:  Peter A Glassman; Barbara Simon; Pamela Belperio; Andrew Lanto
Journal:  Med Care       Date:  2002-12       Impact factor: 2.983

8.  Electronic alerts to prevent venous thromboembolism among hospitalized patients.

Authors:  Nils Kucher; Sophia Koo; Rene Quiroz; Joshua M Cooper; Marilyn D Paterno; Boris Soukonnikov; Samuel Z Goldhaber
Journal:  N Engl J Med       Date:  2005-03-10       Impact factor: 91.245

Review 9.  Reasons For Physicians Not Adopting Clinical Decision Support Systems: Critical Analysis.

Authors:  Saif Khairat; David Marc; William Crosby; Ali Al Sanousi
Journal:  JMIR Med Inform       Date:  2018-04-18

10.  Driving pressure is not associated with mortality in mechanically ventilated patients without ARDS.

Authors:  Michael J Lanspa; Ithan D Peltan; Jason R Jacobs; Jeffrey S Sorensen; Lori Carpenter; Jeffrey P Ferraro; Samuel M Brown; Jay G Berry; Raj Srivastava; Colin K Grissom
Journal:  Crit Care       Date:  2019-12-27       Impact factor: 19.334

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