Literature DB >> 35796991

Translation Phases in Eukaryotes.

Sandra Blanchet1, Namit Ranjan2.   

Abstract

Protein synthesis in eukaryotes is carried out by 80S ribosomes with the help of many specific translation factors. Translation comprises four major steps: initiation, elongation, termination, and ribosome recycling. In this review, we provide a comprehensive list of translation factors required for protein synthesis in yeast and higher eukaryotes and summarize the mechanisms of each individual phase of eukaryotic translation.
© 2022. The Author(s).

Entities:  

Keywords:  Ribosome; Translation; Yeast; mRNA; tRNA

Mesh：

Year:  2022        PMID： 35796991     DOI： 10.1007/978-1-0716-2501-9_13

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  60 in total

1.  Structural roles for human translation factor eIF3 in initiation of protein synthesis.

Authors:  Bunpote Siridechadilok; Christopher S Fraser; Richard J Hall; Jennifer A Doudna; Eva Nogales
Journal:  Science       Date:  2005-12-02       Impact factor: 47.728

2.  The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection.

Authors:  Tatyana V Pestova; Victoria G Kolupaeva
Journal:  Genes Dev       Date:  2002-11-15       Impact factor: 11.361

Review 3.  The elongation, termination, and recycling phases of translation in eukaryotes.

Authors:  Thomas E Dever; Rachel Green
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-07-01       Impact factor: 10.005

4.  eIF5A Functions Globally in Translation Elongation and Termination.

Authors:  Anthony P Schuller; Colin Chih-Chien Wu; Thomas E Dever; Allen R Buskirk; Rachel Green
Journal:  Mol Cell       Date:  2017-04-06       Impact factor: 17.970

Review 5.  The mechanism of eukaryotic translation initiation and principles of its regulation.

Authors:  Richard J Jackson; Christopher U T Hellen; Tatyana V Pestova
Journal:  Nat Rev Mol Cell Biol       Date:  2010-02       Impact factor: 94.444

6.  Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing.

Authors:  Ivan B Lomakin; Victoria G Kolupaeva; Assen Marintchev; Gerhard Wagner; Tatyana V Pestova
Journal:  Genes Dev       Date:  2003-11-04       Impact factor: 11.361

7.  Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes.

Authors:  Andrey V Pisarev; Victoria G Kolupaeva; Marat M Yusupov; Christopher U T Hellen; Tatyana V Pestova
Journal:  EMBO J       Date:  2008-05-08       Impact factor: 11.598

8.  The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome.

Authors:  Lori A Passmore; T Martin Schmeing; David Maag; Drew J Applefield; Michael G Acker; Mikkel A Algire; Jon R Lorsch; V Ramakrishnan
Journal:  Mol Cell       Date:  2007-04-13       Impact factor: 17.970

Review 9.  The mechanism of eukaryotic translation initiation: new insights and challenges.

Authors:  Alan G Hinnebusch; Jon R Lorsch
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-10-01       Impact factor: 9.708

10.  Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.

Authors:  Jose L Llácer; Tanweer Hussain; Laura Marler; Colin Echeverría Aitken; Anil Thakur; Jon R Lorsch; Alan G Hinnebusch; V Ramakrishnan
Journal:  Mol Cell       Date:  2015-07-23       Impact factor: 17.970
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