| Literature DB >> 35670230 |
Jean-Francois Marier1, Nathan Teuscher1, Mohamad-Samer Mouksassi1,2,3.
Abstract
The current tutorial describes why forest plots are needed for an effective communication of covariates effects, how they are constructed, and how they should be presented. Simulation-based methodologies allowing the user to evaluate the marginal impact of changing one covariate at a time or by considering the joint effects of correlated covariates are introduced along with graphical tools for an optimal assessment of the covariate effects. The R package coveffectsplot and an associated R Shiny application are provided to facilitate the design and construction of forest plots for the visualization of covariate effects. All codes and materials are available on a public Github repository.Entities:
Mesh:
Year: 2022 PMID: 35670230 PMCID: PMC9574733 DOI: 10.1002/psp4.12829
Source DB: PubMed Journal: CPT Pharmacometrics Syst Pharmacol ISSN: 2163-8306