Literature DB >> 3566126

Experimental colorectal cancer as a model of human disease.

J M Gilbert.   

Abstract

Colorectal cancer may now be induced consistently in experimental animals by the carcinogen 1,2-dimethylhydrazine (DMH). Adenomas and adenocarcinomas are produced in the large bowel and these resemble human colorectal cancer both macroscopically, and in their clinical behaviour. They are a close model of human disease and may be used for the evaluation of anti-cancer therapies and for the development of a diagnostic test for colorectal cancer.

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Year:  1987        PMID： 3566126      PMCID： PMC2498367     

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN： 0035-8843            Impact factor:   1.891


  26 in total

1.  CARCINOGENIC PROPERTIES OF NUTS FROM CYCAS CIRCINALIS L. INDIGENOUS TO GUAM.

Authors:  G L LAQUEUR; O MICKELSEN; M G WHITING; L T KURLAND
Journal:  J Natl Cancer Inst       Date:  1963-10       Impact factor: 13.506

Review 2.  Experimental colon cancer.

Authors:  J T LaMont; T A O'Gorman
Journal:  Gastroenterology       Date:  1978-12       Impact factor: 22.682

3.  The effect of surgical resection of experimental "primary" adenocarcinoma of the colon of survival and incidence of metastases.

Authors:  D C McCall; R Lawrence; I S Goldenberg
Journal:  Cancer       Date:  1977-10       Impact factor: 6.860

4.  Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas.

Authors:  T H Corbett; D P Griswold; B J Roberts; J C Peckham; F M Schabel
Journal:  Cancer       Date:  1977-11       Impact factor: 6.860

5.  The Hunterian Professors and Arris and Gale Lecturers.

Authors:  H Ellis
Journal:  Ann R Coll Surg Engl       Date:  1979-01       Impact factor: 1.891

6.  Results of treatment of carcinoma of the colon and rectum.

Authors:  G Slaney
Journal:  Mod Trends Surg       Date:  1971

7.  The induction of intestinal neoplasms in rats with the glycoside cycasin and its aglycone.

Authors:  G L Laqueur
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1965-12-21

8.  Transplantable colon tumors as chemotherapy screening models.

Authors:  C R Ball; J A Double
Journal:  Cancer       Date:  1975-12       Impact factor: 6.860

9.  Chemotherapy studies in autochthonous rat tumors intestinal cancer.

Authors:  F Sych; M Habs; D Schmähl
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978-08-24

10.  Experimental investigations on the influence upon the chemical carcinogenesis. IIIrd communication: studies with 1,2-dimethylhydrazine.

Authors:  D Schmähl; A Danisman; M Habs; B Diehl
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1976-05-03
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  1 in total

1.  A new rat colon cancer cell line metastasizes spontaneously: biologic characteristics and chemotherapeutic response.

Authors:  Y Inoue; Y Kashima; K Aizawa; K Hatakeyama
Journal:  Jpn J Cancer Res       Date:  1991-01
  1 in total

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