Melissa Lopez-Pentecost1, Tracy E Crane2,3, David O Garcia4, Lindsay N Kohler4, Betsy C Wertheim2, James R Hebert5,6, Susan E Steck5, Nitin Shivappa5,6, Margarita Santiago-Torres7, Marian L Neuhouser7, Irene E Hatsu8, Linda Snetselaar9, Mridul Datta10, Candyce H Kroenke11, Gloria E Sarto12, Cynthia A Thomson2,4. 1. Clinical Translational Sciences, College of Medicine, University of Arizona, Tucson, AZ, USA. 2. University of Arizona Cancer Center, Tucson, AZ, USA. 3. Biobehavioral Health Sciences Division, College of Nursing, University of Arizona, Tucson, AZ, USA. 4. Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA. 5. Department of Epidemiology and Biostatistics and Cancer Prevention and Control Program, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA. 6. Connecting Health Innovations LLC, Columbia, SC, USA. 7. Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchison Cancer Research Center, Seattle, WA, USA. 8. Department of Human Sciences, College of Education and Human Ecology, Ohio State University, OH, USA. 9. Department of Epidemiology, University of Iowa, Iowa City, IA, USA. 10. Department of Food Science and Human Nutrition, Iowa State University, Ames, IA, USA. 11. Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA. 12. Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Abstract
Aim: To investigate the association between dietary patterns and total and obesity-related cancers risk. Additionally, to examine if acculturation modifies this relationship. Subject and Methods: Dietary intake of postmenopausal Hispanic women (N=5,482) enrolled in the Women's Health Initiative was estimated from a Food Frequency Questionnaire and used to calculate dietary pattern scores; Healthy Eating Index-2015 (HEI-2015), Mexican Diet (MexD) score, alternate Mediterranean Diet Score (aMED), and the energy adjusted-Dietary Inflammatory Index (E-DII™). Associations were evaluated using Cox proportional hazards regression models. Results: 631 cancers and 396 obesity-related cancers were diagnosed over a mean-follow up of 12 years. Across dietary scores, there were no significant associations with cancer risk or mortality. Trend analysis suggest a potentially lower risk for total cancer related to the highest MexD score (HR 0.68, 95% CI 0.45-1.04, P-trend=0.03), and lower risk for obesity-related cancer mortality related to the highest score category for MexD (HR 0.65, 95% CI 0.37-1.16, P-trend=0.02), and aMED (HR 0.87, 95% CI 0.45-1.67, P-trend=0.04). Further analysis suggests less acculturated women with higher MexD scores had 56% lower risk for any cancer (HR 0.44, 95% CI 0.22-0.88, P-trend=0.03) and 83% lower risk for cancer mortality (HR 0.17, 95% CI 0.04-0.76, P-trend=0.01) compared to more acculturated Hispanic women. Conclusions: Dietary patterns were not associated with cancer risk and mortality in postmenopausal Hispanic women. Less-acculturated, Spanish-preferred speakers, who reported consuming a more traditional Mexican diet may experience a lower risk for cancer and cancer mortality.
Aim: To investigate the association between dietary patterns and total and obesity-related cancers risk. Additionally, to examine if acculturation modifies this relationship. Subject and Methods: Dietary intake of postmenopausal Hispanic women (N=5,482) enrolled in the Women's Health Initiative was estimated from a Food Frequency Questionnaire and used to calculate dietary pattern scores; Healthy Eating Index-2015 (HEI-2015), Mexican Diet (MexD) score, alternate Mediterranean Diet Score (aMED), and the energy adjusted-Dietary Inflammatory Index (E-DII™). Associations were evaluated using Cox proportional hazards regression models. Results: 631 cancers and 396 obesity-related cancers were diagnosed over a mean-follow up of 12 years. Across dietary scores, there were no significant associations with cancer risk or mortality. Trend analysis suggest a potentially lower risk for total cancer related to the highest MexD score (HR 0.68, 95% CI 0.45-1.04, P-trend=0.03), and lower risk for obesity-related cancer mortality related to the highest score category for MexD (HR 0.65, 95% CI 0.37-1.16, P-trend=0.02), and aMED (HR 0.87, 95% CI 0.45-1.67, P-trend=0.04). Further analysis suggests less acculturated women with higher MexD scores had 56% lower risk for any cancer (HR 0.44, 95% CI 0.22-0.88, P-trend=0.03) and 83% lower risk for cancer mortality (HR 0.17, 95% CI 0.04-0.76, P-trend=0.01) compared to more acculturated Hispanic women. Conclusions: Dietary patterns were not associated with cancer risk and mortality in postmenopausal Hispanic women. Less-acculturated, Spanish-preferred speakers, who reported consuming a more traditional Mexican diet may experience a lower risk for cancer and cancer mortality.
Entities:
Keywords:
Dietary pattern; Hispanic women; Mexican diet; acculturation; cancer
Authors: Cynthia A Thomson; Marjorie L McCullough; Betsy C Wertheim; Rowan T Chlebowski; Maria Elena Martinez; Marcia L Stefanick; Thomas E Rohan; Joann E Manson; Hilary A Tindle; Judith Ockene; Mara Z Vitolins; Jean Wactawski-Wende; Gloria E Sarto; Dorothy S Lane; Marian L Neuhouser Journal: Cancer Prev Res (Phila) Date: 2014-01
Authors: Nitin Shivappa; Antonella Zucchetto; Diego Serraino; Marta Rossi; Carlo La Vecchia; James R Hébert Journal: Cancer Causes Control Date: 2015-07-25 Impact factor: 2.506
Authors: Marcia L Stefanick; Barbara B Cochrane; Judith Hsia; David H Barad; James H Liu; Susan R Johnson Journal: Ann Epidemiol Date: 2003-10 Impact factor: 3.797
Authors: Nitin Shivappa; James R Hébert; Valentina Rosato; Marta Rossi; Maurizio Montella; Diego Serraino; Carlo La Vecchia Journal: Cancer Causes Control Date: 2016-06-04 Impact factor: 2.506
Authors: Nitin Shivappa; Susan E Steck; Thomas G Hurley; James R Hussey; James R Hébert Journal: Public Health Nutr Date: 2013-08-14 Impact factor: 4.022