| Literature DB >> 35406102 |
Chiara Medoro1, Marta Cianciabella1, Massimiliano Magli1, Giulia Maria Daniele1, Nico Lippi1, Edoardo Gatti1, Roberto Volpe2, Vincenzo Longo3, Filomena Nazzaro4, Silvia Mattoni5, Federica Tenaglia6, Stefano Predieri1.
Abstract
The containment measures due to the COVID-19 pandemic affected food-related activities, influencing dietary behavior, food habits, and dietary choices. This study aimed to compare the relationship between food involvement and dietary choices before and during the pandemic, investigating the role played by food in dietary habits. Responses given by 2773 Italian consumers to an online survey were studied through the Food Involvement Scale (FIS) and correlated to eating habits. FIS scores were then used to explain the importance given to food in circumstances related to well-being, health, and protection against COVID-19 and used to study the relationship between FIS and bioactive compound knowledge, use, and efficacy against COVID-19. The consumers more involved in food issues recognized the importance of food in circumstances related to well-being, health, and protection against COVID-19 and improved their diet during the pandemic. Moreover, consumers who gave more importance to food also revealed higher attention to the use of healthy substances, such as bioactive compounds, considering them effective against COVID-19. These results showed that food experiencing and involvement could be important elements to promote healthy dietary habits that are essential to maintain physical and mental health during emergency periods such as the COVID-19 pandemic.Entities:
Keywords: COVID-19; bioactive compounds; efficacy against COVID-19; food habits; food involvement scale; food quality; probiotics
Mesh:
Year: 2022 PMID: 35406102 PMCID: PMC9003202 DOI: 10.3390/nu14071490
Source DB: PubMed Journal: Nutrients ISSN: 2072-6643 Impact factor: 5.717
General characteristics of the study participants (n = 2773).
|
| % | |
|---|---|---|
| Gender | ||
| Female | 1790 | 64.6 |
| Male | 983 | 35.4 |
| Age (years) | ||
| 21–40 | 48 | |
| 41–65 | 52 | |
| Geographic area | ||
| North west | 858 | 30.9 |
| North east | 879 | 31.7 |
| Center | 498 | 18.0 |
| South and islands | 538 | 19.4 |
| Occupation | ||
| Unemployed | 232 | 8.4 |
| Employed | 1727 | 62.3 |
| Retired | 61 | 2.2 |
| Student | 718 | 25.9 |
| Missing | 35 | 1.3 |
Two-way ANOVA model on FIS score, SD score, and PE score with an interaction (fixed factors: gender and age) for the whole population considered. The FIS scale ranged from 12 to 84.
| Gender | Age | Gender × Age | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Female | Male |
| F | 21–40 | 41–65 |
| F |
| F | |
| FIS score | 63.3 | 59.7 | <0.001 | 87.5 | 61.4 | 61.7 | 0.423 | 0.7 | 0.122 | 2.4 |
| SD | 16.7 | 15.4 | <0.001 | 103.3 | 15.7 | 16.4 | <0.001 | 31.4 | 0.971 | 0.00 |
| PE | 46.6 | 44.3 | <0.001 | 48.3 | 45.7 | 45.3 | 0.209 | 1.6 | 0.073 | 3.2 |
Pearson’s correlation coefficients on general habit changes during the COVID-19 pandemic and FIS score. * p < 0.05 level; ** p < 0.01.
| FIS Score | Physical Activity | Weight Gain | Food Quality | Food Amount (Breakfast) | Food Amount (Lunch) | Food Amount (Dinner) | Food Amount–(between Meals) | Cooking Time | Eating Time | Food Changes for Prevention | Changes Due to Economics | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FIS score | 1 | 0.03 | 0.02 | 0.16 ** | 0.03 | 0.06 ** | 0.02 | −0.01 | 0.23 ** | 0.13 ** | −0.02 | 0.05 * |
|
| 0.112 | 0.269 | <0.001 | 0.113 | 0.004 | 0.351 | 0.701 | <0.001 | <0.001 | 0.267 | 0.016 | |
| Physical activity | 0.03 | 1 | −0.28 | 0.13 ** | 0.05 ** | −0.08 | −0.09 | −0.08 | 0.03 | 0.07 ** | −0.02 | 0.09 ** |
|
| 0.112 | <0.001 | <0.001 | 0.006 | <0.001 | <0.001 | <0.001 | 0.180 | 0.001 | 0.308 | <0.001 | |
| Weight gain | 0.021 | −0.28 | 1 | −0.02 | 0.06 ** | 0.24 ** | 0.26 ** | 0.18 ** | 0.08 ** | 0.04 * | 0.07 ** | 0.01 |
|
| 0.269 | <0.001 | 0.222 | 0.003 | <0.001 | <0.001 | <0.001 | <0.001 | 0.023 | <0.001 | 0.527 | |
| Food quality | 0.155 ** | 0.13 ** | −0.02 | 1 | 0.12 ** | 0.12 ** | 0.08 ** | 0.02 | 0.36 ** | 0.29 ** | −0.12 | 0.15 ** |
|
| <0.001 | <0.001 | 0.222 | <0.001 | <0.001 | <0.001 | 0.309 | <0.001 | <0.001 | <0.001 | <0.001 | |
| Food amount (breakfast) | 0.03 | 0.05 ** | 0.06 ** | 0.12 ** | 1 | 0.34 ** | 0.27 ** | 0.20 ** | 0.12 ** | 0.07 ** | −0.02 | 0.03 |
|
| 0.113 | 0.006 | 0.003 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.214 | 0.094 | |
| Food amount (lunch) | 0.06 ** | −0.08 | 0.24 ** | 0.12 ** | 0.34 ** | 1 | 0.52 ** | 0.36 ** | 0.14 ** | 0.15 ** | −0.06 | −0.09 |
|
| 0.004 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.003 | <0.001 | |
| Food amount (dinner) | 0.02 | −0.09 | 0.26 ** | 0.08 ** | 0.27 ** | 0.52 ** | 1 | 0.39 ** | 0.10 ** | 0.11 ** | −0.02 | −0.07 |
|
| 0.351 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.396 | <0.001 | |
| Food amount–(between meals) | −0.01 | −0.08 | 0.1813 ** | 0.02 | 0.20 ** | 0.36 ** | 0.39 ** | 1 | 0.06 ** | 0.08 ** | −0.08 | −0.09 |
|
| 0.701 | <0.001 | <0.001 | 0.309 | <0.001 | <0.001 | <0.001 | 0.001 | <0.001 | <0.001 | <0.001 | |
| Cooking time | 0.225 ** | 0.03 | 0.08 ** | 0.360 ** | 0.12 ** | 0.14 ** | 0.10 ** | 0.06 ** | 1 | 0.30 ** | 0.02 | 0.13 ** |
|
| <0.001 | 0.180 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 | <0.001 | 0.384 | <0.001 | |
| Eating time | 0.13 ** | 0.06 ** | 0.04 * | 0.29 ** | 0.07 ** | 0.15 ** | 0.11 ** | 0.08 ** | 0.30 ** | 1 | −0.08 | 0.01 |
|
| <0.001 | 0.001 | 0.023 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.450 | |
| Food changes for prevention | −0.02 | −0.02 | 0.07 ** | −0.12 | −0.02 | −0.06 | −0.02 | −0.08 | 0.02 | −0.08 | 1 | 0.35 ** |
|
| 0.267 | 0.308 | <0.001 | <0.001 | 0.214 | 0.003 | 0.396 | <0.001 | 0.384 | <0.001 | <0.001 | |
| Changes due to economics | 0.05 * | 0.09 ** | 0.01 | 0.15 ** | 0.03 | −0.09 | −0.07 | −0.09 | 0.13 ** | 0.01 | 0.35 ** | 1 |
|
| 0.016 | <0.001 | 0.527 | <0.001 | 0.094 | <0.001 | <0.001 | <0.001 | <0.001 | 0.450 | <0.001 |
Three-way ANOVA model on the importance given to food to help recover in some circumstances. FIS group, gender, and age were used as fixed factors with the interactions FIS group × Age and FIS group × Gender. Tuckey’s post hoc test was also used to test the differences between the FIS groups.
| Food | FIS Group | Gender | Age | FIS Group × Gender | FIS Group × Age | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | Medium | High |
| F | Female | Male |
| F | 21–40 | 41–65 |
| F |
| F |
| F | |
| Meat | 2.6 | 2.6 | 2.6 | 0.764 | 0.3 | 2.5 | 2.7 | <0.001 | 19.2 | 2.7 | 2.5 | <0.001 | 20.59 | 0.378 | 1.0 | 0.743 | 0.3 |
| Fish | 1.9 b | 2.0 a | 2.1 a | <0.001 | 16.1 | 2.0 | 2.8 | 0.006 | 7.6 | 2.0 | 2.0 | 0.157 | 2.00 | 0.225 | 1.5 | 0.517 | 0.7 |
| Vegetables | 3.5 c | 3.8 b | 4.0 a | <0.001 | 56.8 | 4.0 | 3.6 | <0.001 | 106.5 | 3.8 | 3.8 | 0.897 | 0.02 | 0.442 | 0.8 | 0.026 | 3.6 |
| Fruit | 3.4 c | 3.6 b | 3.8 a | <0.001 | 19.0 | 3.6 | 3.6 | 0.137 | 2.2 | 3.5 | 3.7 | <0.001 | 35.67 | 0.627 | 0.5 | 0.366 | 1.0 |
| Bread and pasta | 3.6 | 3.60 | 3.7 | 0.078 | 2.6 | 3.6 | 3.6 | 0.244 | 1.4 | 3.7 | 3.5 | <0.001 | 35.58 | 0.639 | 0.5 | 0.132 | 2.0 |
| Cheese | 2.8 | 2.8 | 2.8 | 0.576 | 0.6 | 2.8 | 2. 9 | 0.001 | 11.6 | 2.9 | 2.8 | 0.003 | 8.85 | 1.030 | 0.4 | 0.897 | 0.1 |
a, b, c: Means with different letters correspond to statistical differences (p < 0.05).
Three-way ANOVA model on food consumption frequency in the pre-COVID period. FIS group, gender, and age were used as fixed factors with the interactions FIS group × Age and FIS group × Gender. Tuckey’s post hoc test was also used to test the differences between the FIS groups.
| Topic | FIS Group | Gender | Age | FIS Group × Gender | FIS Group × Age | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | Medium | High |
| F | Female | Male |
| F | 21–40 | 41–65 |
| F |
| F |
| F | |
| Health improving | 5.7 c | 6.2 b | 6.5 a | <0.001 | 111.0 | 6.3 | 6.0 | <0.001 | 45.4 | 1 | 6 | 0.776 | 0.1 | 0.017 | 4.1 | 0.505 | 0.7 |
| Strengthen immune system | 5.5 c | 5.9 b | 6.3 a | <0.001 | 90.1 | 6.1 | 5.7 | <0.001 | 58.7 | 1 | 6 | 0.420 | 0.7 | 0.009 | 4.8 | 0.304 | 1191 |
| Illness recovering | 5.5 c | 5.9 b | 6.2 a | <0.001 | 70.9 | 6.0 | 5.7 | <0.001 | 43.2 | 1.15 | 6 | 0.001 | 12.0 | 0.047 | 3.1 | 0.316 | 1.2 |
| Maintain physical energy | 5.7 c | 6.1 b | 6.4 a | <0.001 | 92.7 | 6.3 | 5.9 | <0.001 | 63.5 | 0.30 | 6 | 0.030 | 4.7 | 0.018 | 4.0 | 0.743 | 0.3 |
| Maintain mental skills | 5.5 c | 5.9 b | 6.3 a | <0.001 | 121.2 | 6.1 | 5.7 | <0.001 | 67.1 | 1 | 6 | 0.103 | 2.7 | <0.001 | 8.9 | 0.341 | 1.1 |
| Maintain serenity | 5.5 c | 6.0 b | 6.4 a | <0.001 | 147.4 | 6.1 | 5.8 | <0.001 | 39.3 | 2 | 6 | 0.671 | 0.2 | 0.077 | 2.6 | 0.197 | 1.6 |
| COVID-19 infection control | 2.9 b | 3.0 b | 3.2 a | 0.006 | 5.1 | 3.1 | 3.1 | 0.178 | 1.8 | 0.33 | 3 | 0.003 | 8.6 | 0.534 | 0.6 | 0.722 | 0.3 |
| Restrain COVID-19 infection effects | 4.2 b | 4.0 b | 4.6 a | <0.001 | 23.7 | 4.3 | 4.2 | 0.049 | 3.9 | 4 | 4 | 0.011 | 6.5 | 0.213 | 1.6 | 0.025 | 3.7 |
| Recover from COVID-19 | 4.8 c | 5.2 b | 5.3 a | <0.001 | 25.1 | 5.2 | 5.0 | <0.001 | 12.8 | 5 | 5 | 533 | <0.001 | 0.261 | 1.3 | 0.510 | 0.7 |
| Mitigate COVID-19 vaccine side effects | 3.2 b | 3.3 b | 3.5 a | 0.002 | 6.0 | 3.3 | 3.4 | 0.537 | 0.4 | 3 | 3 | 3.49 | 0.002 | 0.687 | 0.4 | 0.548 | 0.6 |
a, b, c: Means with different letters correspond to statistical differences (p < 0.05).
Three-way ANOVA model on food variation consumption in the COVID-19 period. FIS group, gender, and age were used as fixed factors with the interactions FIS group × Age and FIS group × Gender. Tuckey’s post hoc test was also used to test the differences between the FIS groups.
| Food | FIS Group | Gender | Age | FIS Group × Gender | FIS Group × Age | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | Medium | High |
| F | Female | Male |
| F | 20–40 | 41–65 |
| F |
| F |
| F | |
| Pasta | 0.05 | 0.05 | 0.00 | 0.576 | 0.6 | −0.01 | 0.08 | 0.048 | 3.9 | 0.01 | 0.07 | 0.157 | 2.0 | 0.976 | 0.0 | 0.418 | 0.9 |
| Bread | 0.02 | −0.03 | 0.01 | 0.608 | 0.5 | −0.02 | −0.00 | 0.842 | 0.0 | 0.00 | 0.01 | 0.952 | 0.0 | 0.577 | 0.6 | 0.524 | 0.6 |
| Meat | −0.13 | −0.19 | −0.19 | 0.517 | 0.7 | −0.21 | −0.13 | 0.096 | 2.8 | −0.16 | −0.17 | 0.763 | 0.1 | 0.070 | 2.7 | 0.757 | 0.3 |
| Fish | 0.04 | 0.17 | 0.19 | 0.030 | 3.5 | 0.13 | 0.14 | 0.920 | 0 | 0.12 | 0.15 | 0.615 | 0.3 | 2.32 | 0.1 | 0.712 | 0.3 |
| Legume | 0.15 c | 0.31 b | 0.44 a | <0.001 | 15.0 | 0.32 | 0.28 | 0.441 | 0.6 | 0.33 | 0.26 | 0.105 | 2.6 | 0.553 | 0.6 | 0.182 | 1.7 |
| Dairy products | −0.00 | −0.01 | −0.02 | 0.941 | 0.1 | −0.06 | 0.04 | 0.015 | 1.0 | −0.04 | 0.01 | 0.212 | 1.6 | 0.845 | 0.2 | 0.211 | 1.6 |
| Eggs | −0.02 b | 0.07 b | 0.14 a | 0.04 | 5.7 | 0.06 | 0.06 | 0.999 | 0.0 | 0.08 | 0.06 | 0.679 | 0.2 | 0.490 | 0.6 | 0.677 | 0.4 |
| Fruit | 0.35 b | 0.44 b | 0.61 a | <0.001 | 12.2 | 0.45 | 0.48 | 0.45 | 0.5 | 0.47 | 0.47 | 0.982 | 0 | 0.008 | 4.8 | 0.528 | 0.6 |
| Citruses | 0.12 b | 0.26 a | 0.34 a | <0.001 | 9.1 | 0.22 | 0.26 | 0.42 | 0.7 | 0.16 | 0.31 | <0.001 | 12.2 | 0.031 | 3.5 | 0.264 | 1.3 |
| Vegetables | 0.43 c | 0.64 b | 0.82 a | <0.001 | 25.5 | 0.68 | 0.58 | 0.023 | 5.2 | 0.65 | 0.61 | 0.428 | 0.6 | 0.137 | 2.0 | 0.267 | 1.3 |
| Beer and wine | −0.40 | −0.23 | −0.028 | 0.078 | 2.6 | −0.40 | −0.20 | 0.002 | 9.2 | −0.36 | −0.25 | 0.116 | 2.5 | 0.030 | 1.0 | 0.96 | 0.0 |
| Spirits | −0.98 | −0.89 | −1.06 | 0.181 | 1.7 | −1.00 | −0.95 | 0.414 | 0.7 | −1.08 | −0.88 | 0.006 | 7.5 | 0.815 | 0.2 | 0.846 | 0.2 |
| Coffee | 0.12 | 0.13 | 0.12 | 0.989 | 0.0 | 0.14 | 0.11 | 0.976 | 0.0 | 0.12 | 0.12 | 0.995 | 0 | 0.580 | 0.5 | 0.762 | 0.3 |
| Rice | 0.06 b | 0.13 b | 0.25 a | <0.001 | 8.0 | 0.11 | 0.18 | 0.077 | 3.1 | 0.16 | 0.13 | 0.512 | 0.4 | 0.437 | 0.8 | 0.307 | 1.2 |
| Sauces | −0.26 | −0.26 | −0.30 | 0.752 | 0.3 | −0.36 | −0.18 | <0.001 | 15.1 | −0.23 | −0.30 | 0.193 | 1.7 | 0.843 | 0.2 | 0.075 | 2.6 |
| Organic food | −0.11 b | 0.11 b | 0.28 a | <0.001 | 24.2 | 0.15 | 0.03 | 0.014 | 6.0 | 0.19 | 0.01 | <0.001 | 15.4 | 0.065 | 2.7 | 0.963 | 0.0 |
| Light food | −0.14 | −0.07 | −0.03 | 0.143 | 1.9 | −0.01 | −0.15 | 0.003 | 9.0 | 0.08 | −0.23 | <0.001 | 43.8 | 0.504 | 0.7 | 0.304 | 1.2 |
| Food for intolerances | −0.26 | −0.24 | −0.25 | 0.938 | 0.1 | −0.22 | −0.28 | 0.245 | 1.4 | −0.15 | −0.33 | <0.001 | 13.5 | 0.654 | 0.4 | 0.877 | 0.1 |
| Sparkling drinks | −0.61 b | −0.68 a | 0.87 a | 0.002 | 6.0 | −0.72 | −0.72 | 0.954 | 0 | −0.72 | −0.72 | 0.998 | 0 | 0.536 | 0.6 | 0.107 | 2.2 |
a, b, c: Means with different letters correspond to statistical differences (p < 0.05).
Three-way ANOVA model on the knowledge level of different bioactive compounds during the COVID-19 period. FIS group, gender, and age were used as fixed factors with the interactions FIS group × Age and FIS group × Gender. Tuckey’s post hoc test was also used to test the differences between the FIS groups.
| Substance | FIS Group | Gender | Age | FIS Group × Age | FIS Group × Gender | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | Medium | High |
| F | Female | Male |
| F | 21–40 | 41–65 |
| F |
| F |
| F | |
| Fibers | 2.19 b | 2.40 a | 2.46 a | <0.001 | 21.10 | 2.4 | 2.31 | 0.013 | 6.16 | 2.34 | 2.36 | 0.585 | 2.34 | 0.106 | 2.25 | 0.879 | 0.13 |
| Vitamins | 2.20 b | 2.30 ab | 2.37 a | 0.001 | 7.30 | 2.3 | 2.3 | 0.039 | 4.27 | 2.31 | 2.27 | 0.313 | 1.02 | 0.0149 | 1.90 | 0.082 | 2.51 |
| Mineral salts | 1.99 b | 2.13 a | 2.22 a | <0.001 | 11.20 | 2.11 | 2.12 | 0.982 | 0 | 2.11 | 2.12 | 0.812 | 2.11 | 0.506 | 0.68 | 0.35 | 1.05 |
| Supplements | 1.90 b | 1.98 a | 2.08 a | 0.001 | 6.84 | 2.06 | 1.91 | <0.001 | 13.00 | 1.97 | 2 | 0.415 | 1.97 | 0.788 | 0.24 | 0.696 | 0.36 |
| Probiotics | 1.51 c | 1.68 b | 1.86 a | <0.001 | 21.50 | 1.79 | 1.58 | <0.001 | 20.7 | 1.59 | 1.78 | <0.001 | 1.59 | 0.009 | 4.68 | 0.847 | 0.17 |
| Fermented cereals | 1.25 b | 1.41 a | 1.49 a | <0.001 | 10.70 | 1.39 | 1.38 | 0.738 | 0.11 | 1.42 | 1.34 | 0.062 | 1.42 | 0.218 | 1.52 | 0.112 | 2.19 |
| Prebiotics | 1.20 c | 1.31 b | 1.51 a | <0.001 | 16.30 | 1.41 | 1.28 | 0.005 | 8.05 | 1.24 | 1.45 | <0.001 | 1.24 | 0.109 | 2.22 | 0.92 | 0.08 |
| Polyphenols | 0.96 c | 1.11 b | 1.28 a | <0.001 | 18.10 | 1.07 | 1.17 | 0.025 | 5.01 | 0.97 | 1.26 | <0.001 | 0.97 | 0.082 | 2.50 | 0.724 | 0.32 |
| Vitamin C | 2.31 b | 2.46 a | 2.45 a | 0.001 | 7.36 | 2.41 | 2.41 | 0.916 | 0.01 | 2.37 | 2.44 | 0.065 | 2.37 | 0.658 | 0.42 | 0.668 | 0.40 |
| Vitamin D | 2.14 b | 2.25 a | 2.28 a | 0.003 | 5.84 | 2.34 | 2.11 | <0.001 | 42.10 | 2.18 | 2.27 | 0.013 | 2.18 | 0.937 | 0.07 | 0.508 | 0.68 |
| Vitamin A | 1.76 b | 1.88 b | 1.93 a | 0.001 | 7.06 | 1.82 | 1.89 | 0.07 | 3.29 | 1.86 | 1.86 | 0.979 | 1.86 | 0.194 | 1.64 | 0.714 | 0.34 |
| Green tea | 1.94 b | 2.14 a | 2.23 a | <0.001 | 18.50 | 2.14 | 2.06 | 0.062 | 3.50 | 2.12 | 2.08 | 0.364 | 2.12 | 0.775 | 0.26 | 0.612 | 0.49 |
| Propolis | 1.61 c | 1.71 b | 1.85 a | <0.001 | 11.02 | 1.82 | 1.63 | <0.001 | 21.50 | 1.66 | 1.79 | 0.004 | 1.66 | 0.789 | 0.24 | 0.182 | 1.70 |
| Melatonin | 1.52 b | 1.57 ab | 1.59 a | 0.216 | 1.53 | 1.65 | 1.47 | <0.001 | 21.10 | 1.57 | 1.55 | 0.546 | 1.57 | 0.996 | 0 | 0.906 | 0.10 |
| Curcumin | 1.26 b | 1.33 a | 1.56 a | <0.001 | 15.5 | 1.42 | 1.35 | 0.12 | 2.42 | 1.25 | 1.52 | <0.001 | 1.25 | 0.259 | 1.35 | 0.37 | 0.99 |
| Lactoferrin | 0.72 b | 0.76 b | 0.86 a | 0.012 | 4.40 | 0.84 | 0.72 | 0.001 | 11.00 | 0.71 | 0.85 | <0.001 | 0.71 | 0.238 | 1.44 | 0.564 | 0.57 |
| Resveratrol | 0.5 | 0.53 | 0.56 | 0.319 | 1.14 | 0.51 | 0.55 | 0.229 | 1.45 | 0.42 | 0.64 | <0.001 | 0.42 | 0.038 | 3.28 | 0.119 | 2.13 |
| Quercetin | 0.49 | 0.53 | 0.57 | 0.182 | 1.70 | 0.53 | 0.53 | 0.853 | 0.03 | 0.41 | 0.65 | <0.001 | 0.41 | 0.283 | 1.26 | 0.405 | 0.90 |
a, b, c: Means with different letters correspond to statistical differences (p < 0.05).
Contingency tables used to summarize the relationship between bioactive compounds’ efficacy against COVID-19, according to FIS group.
| Substance | Efficacy | FIS Score | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Low | Medium | High | All | ||||||
|
| % |
| % |
| % |
| % | ||
| Fibers | Effective | 67 | 7.10 | 72 | 8.50 | 97 | 9.90 | 236 | 8.50 |
| Not effective | 373 | 39.60 | 314 | 37.10 | 375 | 38.10 | 1062 | 38.30 | |
| Do not know | 503 | 53.30 | 461 | 54.40 | 511 | 52.00 | 1475 | 53.20 | |
| Vitamins * | Effective | 253 | 26.80 | 272 | 32.10 | 336 | 34.20 | 861 | 31 |
| Not effective | 248 | 26.30 | 194 | 22.90 | 211 | 21.50 | 653 | 23.50 | |
| Do not know | 442 | 46.90 | 381 | 45.00 | 436 | 44.40 | 1254 | 45.90 | |
| Mineral salts | Effective | 109 | 11.60 | 100 | 11.80 | 133 | 13.50 | 342 | 12.30 |
| Not effective | 325 | 34.50 | 285 | 33.60 | 308 | 31.30 | 918 | 33.10 | |
| Do not know | 509 | 54.00 | 462 | 54.50 | 542 | 55.10 | 1513 | 54.60 | |
| Supplements | Effective | 154 | 16.30 | 125 | 14.80 | 191 | 19.40 | 470 | 16.90 |
| Not effective | 309 | 32.80 | 264 | 31.20 | 301 | 30.60 | 874 | 31.50 | |
| Do not know | 480 | 50.90 | 458 | 54.10 | 491 | 49.90 | 1429 | 51.50 | |
| Probiotics * | Effective | 90 | 9.50 | 111 | 13.10 | 165 | 16.80 | 366 | 13.20 |
| Not effective | 266 | 28.20 | 223 | 26.30 | 261 | 26.60 | 750 | 27 | |
| Do not know | 587 | 62.20 | 513 | 60.60 | 557 | 56.70 | 1657 | 59.80 | |
| Fermented cereals | Effective | 47 | 5.00 | 37 | 4.40 | 47 | 4.80 | 131 | 4.70 |
| Not effective | 333 | 35.30 | 272 | 32.10 | 333 | 33.90 | 938 | 33.80 | |
| Do not know | 563 | 59.70 | 538 | 63.50 | 603 | 61.30 | 1704 | 61.40 | |
| Prebiotics * | Effective | 74 | 7.80 | 83 | 9.80 | 128 | 13.00 | 285 | 10.30 |
| Not effective | 259 | 27.50 | 197 | 23.30 | 254 | 25.80 | 710 | 25.60 | |
| Do not know | 610 | 64.70 | 567 | 66.90 | 601 | 61.10 | 1778 | 64.10 | |
| Polyphenols | Effective | 66 | 7.00 | 62 | 7.30 | 90 | 9.20 | 218 | 7.90 |
| Not effective | 223 | 23.60 | 188 | 22.20 | 223 | 22.70 | 634 | 22.30 | |
| Do not know | 654 | 69.40 | 597 | 70.50 | 670 | 68.20 | 1921 | 69.30 | |
| Vitamin C | Effective | 284 | 30.10 | 295 | 34.80 | 379 | 38.60 | 958 | 34.50 |
| Not effective | 243 | 25.80 | 189 | 22.30 | 213 | 21.70 | 645 | 23.30 | |
| Do not know | 416 | 44.10 | 363 | 42.90 | 391 | 39.80 | 1170 | 42.20 | |
| Vitamin D | Effective | 272 | 28.80 | 285 | 33.60 | 346 | 35.20 | 903 | 32.60 |
| Not effective | 235 | 24.90 | 188 | 22.20 | 223 | 22.70 | 646 | 23.30 | |
| Do not know | 436 | 46.20 | 374 | 44.20 | 414 | 42.10 | 1224 | 44.10 | |
| Vitamin A | Effective | 130 | 13.80 | 111 | 13.10 | 153 | 15.60 | 394 | 14.20 |
| Not effective | 274 | 29.10 | 222 | 26.20 | 242 | 24.60 | 738 | 26.60 | |
| Do not know | 539 | 57.20 | 514 | 60.70 | 588 | 59.80 | 1641 | 59.20 | |
| Green Tea | Effective | 55 | 5.80 | 50 | 5.90 | 78 | 7.90 | 183 | 6.60 |
| Not effective | 390 | 41.40 | 335 | 39.60 | 385 | 39.20 | 1110 | 40.00 | |
| Do not know | 498 | 52.80 | 462 | 54.50 | 520 | 52.90 | 1480 | 53.40 | |
| Propolis | Effective | 93 | 9.90 | 91 | 10.70 | 142 | 14.40 | 326 | 11.80 |
| Not effective | 320 | 33.90 | 276 | 32.60 | 317 | 32.20 | 913 | 32.90 | |
| Do not know | 530 | 56.20 | 480 | 56.70 | 524 | 53.30 | 1534 | 55.30 | |
| Melatonin | Effective | 53 | 5.60 | 41 | 4.80 | 51 | 5.20 | 145 | 5.20 |
| Not effective | 390 | 41.40 | 337 | 39.80 | 400 | 40.70 | 1127 | 40.60 | |
| Do not know | 500 | 53.00 | 469 | 55.40 | 532 | 54.10 | 1501 | 54.10 | |
| Curcumin | Effective | 70 | 7.40 | 55 | 6.50 | 86 | 8.70 | 211 | 7.60 |
| Not effective | 288 | 30.50 | 224 | 26.40 | 282 | 28.70 | 794 | 28.60 | |
| Do not know | 585 | 62.00 | 568 | 67.10 | 615 | 62.60 | 1768 | 63.80 | |
| Lactoferrin * | Effective | 86 | 9.10 | 79 | 9.30 | 109 | 11.10 | 274 | 9.90 |
| Not effective | 241 | 25.60 | 167 | 19.70 | 205 | 20.90 | 613 | 22.10 | |
| Do not know | 616 | 65.30 | 601 | 71.00 | 669 | 68.10 | 1886 | 68 | |
| Resveratrol | Effective | 32 | 3.40 | 34 | 4.00 | 49 | 5.00 | 115 | 4.1 |
| Not effective | 201 | 21.30 | 147 | 17.40 | 180 | 18.30 | 528 | 19 | |
| Do not know | 710 | 75.30 | 666 | 78.60 | 754 | 76.70 | 2130 | 76.80 | |
| Quercetin | Effective | 46 | 4.90 | 47 | 5.50 | 61 | 6.20 | 154 | 5.60 |
| Not effective | 259 | 27.50 | 197 | 23.30 | 254 | 25.80 | 527 | 19 | |
| Do not know | 700 | 74.20 | 652 | 77.00 | 740 | 75.30 | 2092 | 75.40 | |
Association between efficacy and FIS group for each bioactive compounds was analyzed by chi-square test (* p < 0.05).
Bioactive compound efficacy against COVID-19, according to consumers’ consensus, versus the number of publications related to efficacy against COVID-19 in the Web of Science Platform (WOS) using the search “name of each compound” and “COVID”.
| Substance | Efficacy (%) | Number of Publications |
|---|---|---|
| Vitamin A | 14.2 | 1691 |
| Vitamin D | 32.6 | 1419 |
| Vitamin C | 34.5 | 839 |
| Probiotics | 13.2 | 241 |
| Supplements | 16.9 | 216 |
| Polyphenols | 7.9 | 193 |
| Curcumin | 7.6 | 184 |
| Melatonin | 5.2 | 178 |
| Micronutrients | 12.3 | 94 |
| Green tea | 6.6 | 84 |
| Fibers | 8.5 | 56 |
| Quercetin | 5.6 | 46 |
| Propolis | 11.8 | 42 |
| Vitamins | 31 | 38 |
| Fermented food | 4.7 | 27 |
| Resveratrol | 4.1 | 19 |
| Lactoferrin | 9.9 | 15 |
| Prebiotics | 10.3 | 11 |