| Literature DB >> 35380642 |
Piumee Bandara1, Jane Pirkis2, Angela Clapperton2, Sangsoo Shin2, Lay San Too2, Lennart Reifels2, Sandersan Onie3,4, Andrew Page1, Karl Andriessen2, Karolina Krysinska2, Anna Flego2, Marisa Schlichthorst2, Matthew J Spittal2, Cathrine Mihalopoulos5, Long Khanh-Dao Le5.
Abstract
Importance: Installation of barriers has been shown to reduce suicides. To our knowledge, no studies have evaluated the cost-effectiveness of installing barriers at multiple bridge and cliff sites where suicides are known to occur. Objective: To examine the cost-effectiveness of installing barriers at bridge and cliff sites throughout Australia. Design, Setting, and Participants: This economic evaluation used an economic model to examine the costs, costs saved, and reductions in suicides if barriers were installed across identified bridge and cliff sites over 5 and 10 years. Specific and accessible bridge and cliff sites across Australia that reported 2 or more suicides over a 5-year period were identified for analysis. A partial societal perspective (including intervention costs and monetary value associated with preventing suicide deaths) was adopted in the development of the model. Interventions: Barriers installed at bridge and cliff sites. Main Outcomes and Measures: Primary outcome was return on investment (ROI) comparing cost savings with intervention costs. Secondary outcomes included incremental cost-effectiveness ratio (ICER), comprising the difference in costs between installation of barriers and no installation of barriers divided by the difference in reduction of suicide cases. Uncertainty and sensitivity analyses were undertaken to examine the association of changes in suicide rates with barrier installation, adjustments to the value of statistical life, and changes in maintenance costs of barriers.Entities:
Mesh:
Year: 2022 PMID: 35380642 PMCID: PMC8984771 DOI: 10.1001/jamanetworkopen.2022.6019
Source DB: PubMed Journal: JAMA Netw Open ISSN: 2574-3805
Input Parameters and Uncertainty Ranges for Health Benefit and Costing Analysis of Barriers for Suicide Prevention
| Parameter | IRR (95% CI) | Uncertainty distribution | Source(s) |
|---|---|---|---|
| Effect of barrier installation at bridge sites | 0.16 (0.13-0.20) | Lognormal | Meta-analysis[ |
| Effect of barrier installation at cliff sites | 0.72 (0.50-1.05) | Lognormal | Meta-analysis[ |
| Effect of barrier installation at nearby sites | 1.01 (0.85-1.20) | Lognormal | Meta-analysis[ |
|
| |||
| Unit cost, $ | |||
| Barriers at bridge | 10 459 736 | Fixed | Australian news[ |
| Barriers at cliffs | 1 638 115 | Fixed | Australian news[ |
| Uncertainty, % | ±20 | Pert | Technical reports[ |
| Maintenance cost, % (range) | |||
| Minor | 20 (10-30) | Pert | Own assumption |
| Major | 50 (40-60) | Pert | Own assumption |
| Statistical life year value, $ | 3 093 725 | Fixed | Department of the Prime Minister and Cabinet[ |
Cost-effectiveness Summary for Installing Barriers at Bridge and Cliff Sites Where Suicides are Known to Occur in Australia
| Output parameter | Cost, median (95% UI), $US in millions | |||
|---|---|---|---|---|
| Bridges | Cliff sites | |||
| 5 y | 10 y | 5 y | 10 y | |
| Intervention costs | 86 (82 to 91) | 114 (108 to 120) | 46 (41 to 50) | 74 (67 to 80) |
| Cost offsets | −145 (−90 to −160) | −270 (−176 to −298) | −78 (−147 to 44) | −145 (−274 to 82) |
| Net costs | −58 (−2 to 75) | −156 (−58 to −184) | −32 (−102 to 89) | −71 (−201 to 154) |
| Suicides averted, No. (95% UI) | 50 (31 to 55) | 100 (65 to 110) | 27 (−15 to 51) | 53 (−30 to 101) |
| ROI ratio (95% UI) | 1.7 (1.0 to 1.9) | 2.4 (1.5 to 2.7) | 1.7 (−0.9 to 3.3) | 2.0 (−1.1 to 3.8) |
| ICER (95% UI) | Dominant (dominant to dominant) | Dominant (dominant to dominant) | Dominant (dominant to dominated) | Dominant (dominant to dominated) |
Abbreviations: ICER, incremental cost-effectiveness ratio; ROI, return on investment; UI, uncertainty interval.
Negative costs denote cost savings (if positive costs denote an expense).
A dominant ICER signifies that the intervention is both cost saving and produces greater positive health outcomes when compared with the comparator; a dominated ICER signifies that the intervention is more costly and produces less positive health outcomes when compared with the comparator.
Figure. Cost-effectiveness Plane of Installing Barriers at Known Bridge and Cliff Sites Where Suicides Have Occurred in Australia
ROI Results in Scenario Analysis
| Scenario analyses | ROI ratio, $ (95% UI) | |||
|---|---|---|---|---|
| 5 y | 10 y | |||
| Bridges | Cliff sites | Bridges | Cliff sites | |
| Baseline model | 1.7 (1.0 to 1.9) | 1.7 (−0.9 to 3.3) | 2.4 (1.5 to 2.7) | 2.0 (−1.1 to 3.8) |
| No increased suicide every year | 1.5 (1.0 to 1.7) | 1.7 (−0.8 to 3.3) | 2.0 (1.3 to 2.3) | 2.0 (−1.0 to 3.8) |
| Cost saving estimated by the value of statistical life-year | 0.2 (0.1 to 0.2) | 0.2 (−0.1 to 0.4) | 0.5 (0.3 to 0.6) | 0.4 (−0.2 to 0.9) |
| Lower maintenance | 1.9 (1.2 to 2.1) | 2.2 (−1.0 to 4.1) | 3.1 (2.0 to 3.4) | 3.2 (−1.5 to 5.9) |
| Higher maintenance | 1.6 (1.0 to 1.7) | 1.5 (−0.8 to 2.9) | 2.1 (1.4 to 2.4) | 1.7 (−0.9 to 3.3) |
Abbreviations: ROI, return on investment; UI, uncertainty interval.
ROI ratio indicates US$ saved per US $1 invested.
Estimated minor maintenance cost of 5% and major maintenance cost of 20% of total installation costs.
Estimated minor maintenance cost of 30% and major maintenance cost of 60% of total installation costs.