Literature DB >> 3537008

alpha 1-Antitrypsin: molecular pathology, leukocytes, and tissue damage.

R W Carrell.   

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Year:  1986        PMID: 3537008      PMCID: PMC423882          DOI: 10.1172/JCI112731

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  48 in total

1.  Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants.

Authors:  H Carp; A Janoff
Journal:  Am Rev Respir Dis       Date:  1978-09

Review 2.  Elastase, collagenase, emphysema, and alpha1-antitrypsin deficiency.

Authors:  J Lieberman
Journal:  Chest       Date:  1976-07       Impact factor: 9.410

3.  The oxidative inactivation of human alpha-1-proteinase inhibitor. Further evidence for methionine at the reactive center.

Authors:  D Johnson; J Travis
Journal:  J Biol Chem       Date:  1979-05-25       Impact factor: 5.157

4.  Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder.

Authors:  H L Sharp; R A Bridges; W Krivit; E F Freier
Journal:  J Lab Clin Med       Date:  1969-06

5.  Human alpha 1-antitrypsin expression in Xenopus oocytes. Secretion of the normal (PiM) and abnormal (PiZ) forms.

Authors:  D M Errington; I C Bathurst; R W Carrell
Journal:  Eur J Biochem       Date:  1985-12-02

6.  Natural history and life expectancy in severe alpha1-antitrypsin deficiency, Pi Z.

Authors:  C Larsson
Journal:  Acta Med Scand       Date:  1978

7.  Liver disease in alpha1-antitrypsin deficiency detected by screening of 200,000 infants.

Authors:  T Sveger
Journal:  N Engl J Med       Date:  1976-06-10       Impact factor: 91.245

8.  Liver in alpha1-antitrypsin deficiency: morphologic observations and in vitro synthesis of alpha1-antitrypsin.

Authors:  A K Bhan; R J Grand; H R Colten; C A Alper
Journal:  Pediatr Res       Date:  1976-01       Impact factor: 3.756

9.  Demonstration of granulocytic proteases in plasma of patients with acute leukemia and septicemia with coagulation defects.

Authors:  R Egbring; W Schmidt; G Fuchs; K Havemann
Journal:  Blood       Date:  1977-02       Impact factor: 22.113

10.  Structural evidence for methionine at the reactive site of human alpha-1-proteinase inhibitor.

Authors:  D Johnson; J Travis
Journal:  J Biol Chem       Date:  1978-10-25       Impact factor: 5.157

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  59 in total

1.  The molecular structure and pathology of alpha 1-antitrypsin.

Authors:  R W Carell
Journal:  Lung       Date:  1990       Impact factor: 2.584

Review 2.  Liver disease in infancy: a 20 year perspective.

Authors:  G Mieli-Vergani; E R Howard; A P Mowat
Journal:  Gut       Date:  1991-09       Impact factor: 23.059

Review 3.  Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.

Authors:  R G Crystal
Journal:  J Clin Invest       Date:  1990-05       Impact factor: 14.808

4.  Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.

Authors:  D H Perlmutter; J Travis; P I Punsal
Journal:  J Clin Invest       Date:  1988-06       Impact factor: 14.808

5.  Synthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1-antitrypsin deficiency and liver disease.

Authors:  D H Perlmutter; M J Schlesinger; J A Pierce; P I Punsal; A L Schwartz
Journal:  J Clin Invest       Date:  1989-11       Impact factor: 14.808

6.  Proteomic profiling of urine identifies specific fragments of SERPINA1 and albumin as biomarkers of preeclampsia.

Authors:  Irina A Buhimschi; Guomao Zhao; Edmund F Funai; Nathan Harris; Isaac E Sasson; Ira M Bernstein; George R Saade; Catalin S Buhimschi
Journal:  Am J Obstet Gynecol       Date:  2008-11       Impact factor: 8.661

7.  Increased levels of plasminogen activator inhibitor-1 (PAI-1) in human brain tumors.

Authors:  J S Rao; A Rayford; R A Morantz; B W Festoff; R Sawaya
Journal:  J Neurooncol       Date:  1993-09       Impact factor: 4.130

Review 8.  Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease.

Authors:  Caroline A Owen
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2008

9.  Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency.

Authors:  Caitriona McLean; Catherine M Greene; Noel G McElvaney
Journal:  Biologics       Date:  2009-07-13

10.  Low Serum Alpha-1 Antitrypsin (AAT) in Family Members of Individuals with Autism Correlates with PiMZ Genotype.

Authors:  Anthony J Russo; Lauren Neville; Christine Wroge
Journal:  Biomark Insights       Date:  2009-03-18
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