Literature DB >> 2185272

Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.

R G Crystal1.   

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Year:  1990        PMID： 2185272      PMCID： PMC296579          DOI： 10.1172/JCI114578

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  37 in total

Review 1.  The alpha 1-antitrypsin gene and its deficiency states.

Authors:  R G Crystal
Journal:  Trends Genet       Date:  1989-12       Impact factor: 11.639

2.  Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder.

Authors:  H L Sharp; R A Bridges; W Krivit; E F Freier
Journal:  J Lab Clin Med       Date:  1969-06

3.  Complete sequence of the cDNA for human alpha 1-antitrypsin and the gene for the S variant.

Authors:  G L Long; T Chandra; S L Woo; E W Davie; K Kurachi
Journal:  Biochemistry       Date:  1984-10-09       Impact factor: 3.162

Review 4.  Structure and variation of human alpha 1-antitrypsin.

Authors:  R W Carrell; J O Jeppsson; C B Laurell; S O Brennan; M C Owen; L Vaughan; D R Boswell
Journal:  Nature       Date:  1982-07-22       Impact factor: 49.962

Review 5.  Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis.

Authors:  A Janoff
Journal:  Am Rev Respir Dis       Date:  1985-08

6.  Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals.

Authors:  J F Mornex; A Chytil-Weir; Y Martinet; M Courtney; J P LeCocq; R G Crystal
Journal:  J Clin Invest       Date:  1986-06       Impact factor: 14.808

7.  Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency.

Authors:  S Eriksson; J Carlson; R Velez
Journal:  N Engl J Med       Date:  1986-03-20       Impact factor: 91.245

8.  Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function.

Authors:  H Loebermann; R Tokuoka; J Deisenhofer; R Huber
Journal:  J Mol Biol       Date:  1984-08-15       Impact factor: 5.469

9.  Synthesis in E. coli of alpha 1-antitrypsin variants of therapeutic potential for emphysema and thrombosis.

Authors:  M Courtney; S Jallat; L H Tessier; A Benavente; R G Crystal; J P Lecocq
Journal:  Nature       Date:  1985 Jan 10-18       Impact factor: 49.962

10.  Replacement therapy of alpha 1-antitrypsin deficiency. Reversal of protease-antiprotease imbalance within the alveolar structures of PiZ subjects.

Authors:  J E Gadek; H G Klein; P V Holland; R G Crystal
Journal:  J Clin Invest       Date:  1981-11       Impact factor: 14.808
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  113 in total

Review 1.  Liver injury in alpha1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury.

Authors:  David H Perlmutter
Journal:  J Clin Invest       Date:  2002-12       Impact factor: 14.808

2.  Alpha(1)-Antitrypsin Deficiency.

Authors: 
Journal:  Curr Treat Options Gastroenterol       Date:  2000-12

Review 3.  Molecular biology and respiratory disease. 7. The alpha 1 antitrypsin gene and chronic lung disease.

Authors:  N Kalsheker; K Morgan
Journal:  Thorax       Date:  1990-10       Impact factor: 9.139

Review 4.  Novel treatment strategies for liver disease due to α1-antitrypsin deficiency.

Authors:  Nicholas Maurice; David H Perlmutter
Journal:  Clin Transl Sci       Date:  2012-01-10       Impact factor: 4.689

Review 5.  Alpha-1 antitrypsin deficiency: a commonly overlooked cause of lung disease.

Authors:  Sarah K Brode; Simon C Ling; Kenneth R Chapman
Journal:  CMAJ       Date:  2012-07-03       Impact factor: 8.262

6.  Emphysema mediated by lung overexpression of ADAM10.

Authors:  Hiroki Saitoh; Philip L Leopold; Ben-Gary Harvey; Timothy P O'Connor; Stefan Worgall; Neil R Hackett; Ronald G Crystal
Journal:  Clin Transl Sci       Date:  2009-02       Impact factor: 4.689

7.  A novel alpha1-antitrypsin null variant (PiQ0Milano ).

Authors:  Raffaela Rametta; Gabriella Nebbia; Paola Dongiovanni; Marcello Farallo; Silvia Fargion; Luca Valenti
Journal:  World J Hepatol       Date:  2013-08-27

8.  Mutant fibrinogen cleared from the endoplasmic reticulum via endoplasmic reticulum-associated protein degradation and autophagy: an explanation for liver disease.

Authors:  Kristina B Kruse; Amy Dear; Erin R Kaltenbrun; Brandan E Crum; Peter M George; Stephen O Brennan; Ardythe A McCracken
Journal:  Am J Pathol       Date:  2006-04       Impact factor: 4.307

9.  Changes of immunoreactivity in alpha 1-antitrypsin in patients with autoimmune diseases.

Authors:  L Saso; B Silvestrini; R Lahita; C Y Cheng
Journal:  Inflammation       Date:  1993-06       Impact factor: 4.092

10.  Real time PCR detection of the PI*Z and PI*S mutations associated with alpha-1 antitrypsin deficiency.

Authors:  Claudine L Bartels; Angela L Marchetti; W Edward Highsmith; Gregory J Tsongalis
Journal:  Am J Transl Res       Date:  2009-08-10       Impact factor: 4.060
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