Literature DB >> 3535667

Allium sativum (garlic) inhibits lipid synthesis by Candida albicans.

M Adetumbi, G T Javor, B H Lau.   

Abstract

The effect of aqueous garlic extract on the macromolecular synthesis of Candida albicans was studied. Protein and nucleic acid syntheses were inhibited to the same extent as growth, but lipid synthesis was completely arrested. Blockage of lipid synthesis is likely an important component of the anticandidal activity of garlic.

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Year:  1986        PMID： 3535667      PMCID： PMC180587          DOI： 10.1128/AAC.30.3.499

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Inhibition of growth of zoopathogenic fungi by garlic extract.

Authors:  J A Appleton; M R Tansey
Journal:  Mycologia       Date:  1975 Jul-Aug       Impact factor: 2.696

2.  Enzyme inhibition by allicin, the active principle of garlic.

Authors:  E D WILLS
Journal:  Biochem J       Date:  1956-07       Impact factor: 3.857

3.  Inhibition of fungal growth by garlic extract.

Authors:  M R Tansey; J A Appleton
Journal:  Mycologia       Date:  1975 Mar-Apr       Impact factor: 2.696

4.  The fungicidal and fungistatic effects of an aqueous garlic extract on medically important yeast-like fungi.

Authors:  G S Moore; R D Atkins
Journal:  Mycologia       Date:  1977 Mar-Apr       Impact factor: 2.696

5.  Right to health.

Authors:  R Lai Pong Chong
Journal:  Nouv Com Int Cathol Infirm Assist Med Soc       Date:  1986

6.  Lipids of Salmonella typhimurium and Escherichia coli: structure and metabolism.

Authors:  G F Ames
Journal:  J Bacteriol       Date:  1968-03       Impact factor: 3.490

7.  Isolation and characterization of larvicidal principle of garlic.

Authors:  S V Amonkar; A Banerji
Journal:  Science       Date:  1971-12-24       Impact factor: 47.728

8.  Inhibition of mycobacteria by garlic extract (Allium sativum).

Authors:  E C Delaha; V F Garagusi
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

9.  Mosquito control with active principle of garlic, Allium sativum.

Authors:  S V Amonkar; E L Reeves
Journal:  J Econ Entomol       Date:  1970-08       Impact factor: 2.381

10.  Mutants of Escherichia coli defective in membrane phospholipid synthesis: macromolecular synthesis in an sn-glycerol 3-phosphate acyltransferase Km mutant.

Authors:  R M Bell
Journal:  J Bacteriol       Date:  1974-03       Impact factor: 3.490
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  15 in total

1.  N-thiolated beta-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus.

Authors:  Kevin D Revell; Bart Heldreth; Timothy E Long; Seyoung Jang; Edward Turos
Journal:  Bioorg Med Chem       Date:  2006-12-20       Impact factor: 3.641

2.  Antimicrobial properties of garlic oil against human enteric bacteria: evaluation of methodologies and comparisons with garlic oil sulfides and garlic powder.

Authors:  Z M Ross; E A O'Gara; D J Hill; H V Sleightholme; D J Maslin
Journal:  Appl Environ Microbiol       Date:  2001-01       Impact factor: 4.792

3.  Effectiveness of Natural Antifungal Compounds in Controlling Infection by Grapevine Trunk Disease Pathogens through Pruning Wounds.

Authors:  Rebeca Cobos; Rosa María Mateos; José Manuel Álvarez-Pérez; Miguel Angel Olego; Silvia Sevillano; Sandra González-García; Enrique Garzón-Jimeno; Juan José R Coque
Journal:  Appl Environ Microbiol       Date:  2015-07-10       Impact factor: 4.792

4.  A quantitative assessment of the antimicrobial activity of garlic (Allium sativum).

Authors:  L P Rees; S F Minney; N T Plummer; J H Slater; D A Skyrme
Journal:  World J Microbiol Biotechnol       Date:  1993-05       Impact factor: 3.312

5.  Evidence of increased diversity of methanogenic archaea with plant extract supplementation.

Authors:  S Ohene-Adjei; A V Chaves; T A McAllister; C Benchaar; R M Teather; R J Forster
Journal:  Microb Ecol       Date:  2007-12-13       Impact factor: 4.552

6.  Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression.

Authors:  Uri Sela; Sharon Ganor; Iris Hecht; Alexander Brill; Talia Miron; Aharon Rabinkov; Meir Wilchek; David Mirelman; Ofer Lider; Rami Hershkoviz
Journal:  Immunology       Date:  2004-04       Impact factor: 7.397

7.  Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis.

Authors:  Edward Turos; Kevin D Revell; Praveen Ramaraju; Danielle A Gergeres; Kerriann Greenhalgh; Ashley Young; Nalini Sathyanarayan; Sonja Dickey; Daniel Lim; Mamoun M Alhamadsheh; Kevin Reynolds
Journal:  Bioorg Med Chem       Date:  2008-05-17       Impact factor: 3.641

Review 8.  Garlic revisited: therapeutic for the major diseases of our times?

Authors:  T H Abdullah; O Kandil; A Elkadi; J Carter
Journal:  J Natl Med Assoc       Date:  1988-04       Impact factor: 1.798

9.  Effects of garlic extract treatment in normal and streptozotocin diabetic rats infected with Candida albicans.

Authors:  M Bokaeian; A Nakhaee; Bita Moodi; A Farhangi; Azim Akbarzadeh
Journal:  Indian J Clin Biochem       Date:  2010-05-27

10.  Quantitative and qualitative analysis of the antifungal activity of allicin alone and in combination with antifungal drugs.

Authors:  Young-Sun Kim; Kyung Sook Kim; Ihn Han; Mi-Hyun Kim; Min Hyung Jung; Hun-Kuk Park
Journal:  PLoS One       Date:  2012-06-05       Impact factor: 3.240
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