Literature DB >> 35348916

Molecular characterization of chikungunya virus from the first cluster of patients during the 2020 outbreak in Chad.

Martial Gide Yonga1, Fissou Henry Yandai2, Serge Sadeuh-Mba1, Alsadick Haroun Abdallah3, Diane Ouapi1, Kadidja Gamougam4, Ngu Njei Abanda1, Marie Claire Endengue-Zanga1, Maurice Demanou5, Richard Njouom6.   

Abstract

We sequenced a portion of the E1 envelope protein gene of two of four CHIKV RT-PCR-positive samples from the first cluster of chikungunya patients during the 2020 Chad outbreak. Phylogenetic analysis revealed that the viruses belonged to the East/Central/South/African genotype but lacked the E1 A226V and K211E mutations associated with viral adaptability and transmission, suggesting an autochthonous transmission. These sequences are a useful basis for tracking viral evolution in subsequent outbreaks in Chad.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.

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Year:  2022        PMID： 35348916     DOI： 10.1007/s00705-022-05427-5

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  11 in total

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10.  Molecular characterization of chikungunya virus during the 2019 outbreak in the Democratic Republic of the Congo.

Authors:  Philippe Selhorst; Sheila Makiala-Mandanda; Birgit De Smet; Joachim Mariën; Colin Anthony; Guillaume Binene-Mbuka; Anja De Weggheleire; Gillon Ilombe; Eddy Kinganda-Lusamaki; Elisabeth Pukuta-Simbu; Leopold Lubula; Placide Mbala-Kingebeni; Antoine Nkuba-Ndaye; Florian Vogt; Francis Watsenga; Wim Van Bortel; Veerle Vanlerberghe; Kevin K Ariën; Steve Ahuka-Mundeke
Journal:  Emerg Microbes Infect       Date:  2020-12       Impact factor: 7.163
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