| Literature DB >> 35330425 |
Amir Khosrow Bigdeli1, Florian Falkner1, Benjamin Thomas1, Gabriel Hundeshagen1, Simon Andreas Mayer1, Eva-Maria Risse1, Leila Harhaus1, Emre Gazyakan1, Ulrich Kneser1, Christian Andreas Radu1.
Abstract
INTRODUCTION: Deep sternal wound infections (DSWI) after cardiac surgery pose a significant challenge in reconstructive surgery. In this context, free flaps represent well-established options. The objective of this study was to investigate the clinical outcome after free myocutaneous tensor fasciae latae (TFL) flap reconstruction of sternal defects, with a special focus on surgical complications and donor-site morbidity.Entities:
Keywords: DSWI; TFL flap; deep sternal wound infection; free flap; reconstructive microsurgery; sternal defect reconstruction; tensor fasciae latae flap
Year: 2022 PMID: 35330425 PMCID: PMC8951458 DOI: 10.3390/jpm12030427
Source DB: PubMed Journal: J Pers Med ISSN: 2075-4426
Patient demographics and comorbidities, El Oakley and Wright classification, and microbiological examination (SD = Standard Deviation).
| Patient Demographics | |
|---|---|
| Number of patients and flaps | 46 |
| Mean age (years) ± SD (range) | 67 ± 11 (38 to 85) |
| Median ASA class (range) | 3 (2 to 4) |
| Sex (female/male) | 17/29 |
| Comorbidities | |
| Arterial hypertension (HTN) | 44 (96%) |
| Coronary artery disease (CAD) | 41 (89%) |
| Chronic heart failure (CHF) | 27 (59%) |
| Chronic obstructive pulmonary disease (COPD) | 20 (44%) |
| Chronic kidney disease (CKD) | 25 (54%) |
| Diabetes mellitus (DM) | 30 (65%) |
| Active smoker at time of surgery | 13 (28%) |
| BMI (Body Mass Index) (kg/m2) | 29 ± 6 |
| Obesity (BMI ≥ 30 kg/m2) | 19 (41%) |
| El Oakley and Wright classification | |
| I | - |
| II | - |
| IIIA | 7 (15%) |
| IIIB | 11 (24%) |
| IVA | 2 (4%) |
| IVB | - |
| V | 26 (57%) |
| Microbiological examination of soft and bony tissue | |
|
| 17 (37%) |
| Methicillin-resistant | 6 (13%) |
|
| 14 (30%) |
|
| 10 (22%) |
|
| 7 (15%) |
| Multiresistant Gram-negative bacteria | 9 (20%) |
Figure 1A 62-year-old male patient with DSWI and sternal osteomyelitis after a bilateral CABG procedure. The resulting defect measured 22 × 8 cm (A). Sternal reconstruction with a TFL flap and an AVL was planned. The AVL was created between the subclavian artery and vein in an end-to-side technique using a greater saphenous vein graft (B). Subsequently, arterial and venous end-to-end anastomoses with the TFL flap pedicle were performed (C,D). The patient’s recovery was uneventful, and he was discharged 13 days postoperatively. Stable defect reconstruction without any sign of wound healing disorder or recurrent infection three month after surgery (E).
Operative characteristics (cm = centimeter, cm2 = square-centimeter, min = minute, RIMA = Right Internal Mammary Artery, OT = Operation Time).
| Operative Characteristics | |
|---|---|
| Mean sternal defect size [cm2] ± SD | 194 ± 43 (128 to 297) |
| Mean sternal defect length [cm] ± SD | 23 ± 3 (18 to 27) |
| Mean sternal defect width [cm] ± SD | 8 ± 1 (7 to 11) |
| Mean length of flap ischemia [min] ± SD | 63 ± 16 (32 to 91) |
| Mean skin paddle surface [cm2] ± SD | 205 ± 38 (154 to 308) |
| Mean flap length [cm] ± SD | 24 ± 3 (19 to 28) |
| Mean flap width [cm] ± SD | 8 ± 1 (7 to 11) |
| Mean OT [min] ± SD (range) | 387 ± 120 (212 to 695) |
| Recipient vessel situation | |
| RIMA and concomitant vein | 9 (20%) |
| RIMA and cephalic vein | 15 (33%) |
| Cephalic vein-thoracoacromial artery arterio-venous loop | 3 (7%) |
| Cephalic vein-subclavian artery arterio-venous loop | 10 (22%) |
| Subclavian artery/vein arterio-venous loop using a greater saphenous vein graft | 9 (20%) |
Postoperative complications.
| Surgical Complications | |
|---|---|
|
| |
| Arterial thrombosis | 2 (4%) |
| Venous thrombosis | 1 (2%) |
| Hematoma | 5 (11%) |
| Wound dehiscence | 3 (7%) |
| Partial flap necrosis (>5% of the skin paddle) | 3 (7%) |
| Donor-site complications | |
| Impaired wound healing | 3 (7%) |
| Wound infection | 1 (2%) |
| Hematoma | 1 (2%) |
Follow-up examination (VSS = Vancouver Scar Scale, POSAS = Patient and Observer Scar Assessment Scale, SD = Standard Deviation).
| Follow-Up Examinations | |||
|---|---|---|---|
|
|
|
|
|
| Mean knee joint extension/flexion (mean ± SD) | 110° ± 9° | 114° ± 9° | |
| Mean hip joint extension/flexion (mean ± SD) | 118° ± 10° | 122° ± 8° | |
| Mean hip joint abduction/adduction (mean ± SD) | 69° ± 5° | 71° ± 6° | |
| Mean hip internal-/external rotation (mean ± SD) | 58° ± 7° | 62° ± 7° | |
|
|
|
| |
| Median VSS (range) | 3 (2 to 7) | 3 (2 to 5) | - |
| Median POSAS (range) | 24 (18 to 34) | 23 (19 to 31) | - |
| Median patients’ scar assessment (range) | 12 (9 to 21) | 12 (10 to 16) | - |
| Median observers’ scar assessment (range) | 11 (9 to 17) | 11 (9 to 15) | - |