| Literature DB >> 35329280 |
Zheng-An Lu1, Le Shi1, Jian-Yu Que1, Yong-Bo Zheng1,2, Qian-Wen Wang1, Wei-Jian Liu1, Yue-Tong Huang1, Xiao-Xing Liu1, Kai Yuan1, Wei Yan1, Jie Shi3, Yan-Ping Bao3, Lin Lu1,2,3.
Abstract
Digital mental health services (DMHSs) have great potential for mitigating the mental health burden related to COVID-19, but public accessibility (ease of acquiring services when needed) to DMHSs during the pandemic is largely unknown. Accessibility to DMHSs was tracked longitudinally among a nationwide sample of 18,804 adults in China from before to one year after COVID-19 outbreak. Unconditional and conditional latent growth curve models and latent growth mixture models were fitted to explore the overall growth trend, influencing factors, and latent trajectory classes of accessibility to DMHSs throughout COVID-19. Generalized estimating equation models and generalized linear mixed models were employed to explore the association between accessibility to DMHSs and long-term mental health symptoms. We found that people generally reported increased difficulty in accessing DMHSs from before to one year after COVID-19 outbreak. Males, youngsters, individuals with low socioeconomic status, and individuals greatly affected by COVID-19 reported greater difficulty in accessing DMHSs. Four DMHS accessibility trajectory classes were identified: "lowest-great increase" (6.3%), "moderate low-slight increase" (44.4%), "moderate high-slight decrease" (18.1%) and "highest-great decrease" (31.2%). Trajectory classes reporting greater difficulty in accessing DMHSs were at higher risk for long-term mental symptoms. In conclusion, an overall increase in difficulty in accessing DMHSs is observed throughout COVID-19, and heterogeneity exists in DMHS accessibility trajectories. Our results suggest that easy access to DMHSs should be consistently facilitated. Moreover, access gaps should be reduced across demographic groups, and target populations for service allocation should alter as the pandemic evolves.Entities:
Keywords: COVID-19; accessibility; digital mental health services; trajectory
Mesh:
Year: 2022 PMID: 35329280 PMCID: PMC8955845 DOI: 10.3390/ijerph19063593
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Figure 1Flow graph for participants recruitment in three surveys.
Figure 2Procedures for statistical analyses.
Demographic and epidemic-related characteristics of the longitudinal sample.
| Factors | No. (%)/Mean (SD) |
|---|---|
| Overall | 18,804 (100.0) |
| Gender | |
| Male | 8558 (45.5) |
| Female | 10,246 (54.5) |
| Mean for age (SD) | 36.6 (8.2) |
| Age group (years) | |
| 18–39 | 12,364 (65.8) |
| ≥40 | 6440 (34.2) |
| Living area | |
| Urban | 17,599 (93.6) |
| Rural | 1205 (6.4) |
| Educational level | |
| College school or higher | 15,489 (82.4) |
| Lower than college school | 3315 (17.6) |
| Marital status | |
| Married | 14,783 (78.6) |
| Unmarried | 4021 (21.4) |
| Income level (CNY) | |
| 0–4999 | 4186 (22.3) |
| ≥5000 | 14,618 (77.7) |
| History of chronic diseases | |
| Yes | 1201 (6.4) |
| Unknown/no | 17,603 (93.6) |
| History of mental disorders | |
| Yes | 122 (0.6) |
| Unknown/no | 18,682 (99.4) |
| Family history of mental disorders | |
| Yes | 235 (1.2) |
| Unknown/no | 18,569 (98.8) |
Figure 3Trajectory of accessibility to DMHSs from before to one year after COVID-19 outbreak. Higher scores indicate lower accessibility level (more difficult to access DMHSs). Raw mean accessibility scores (SD) are presented at each time point.
Influencing factors of the intercept and slope of perceived accessibility to DMHSs from the conditional latent growth curve model.
| Influencing Factors of the Intercept | B (SE) | |
|---|---|---|
| Gender: male (vs. female) | 0.11 (0.04) | 0.008 |
| Age group: 18–39 (vs. ≥40) | 0.34 (0.04) | <0.001 |
| Living area: urban (vs. rural) | −0.13 (0.08) | 0.12 |
| Educational level: college school or higher (vs. lower than college school) | 0.07 (0.06) | 0.24 |
| Marital status: married (vs. unmarried) | −0.01 (0.05) | 0.87 |
| Family monthly income: 0–4999 (vs. ≥5000) | 0.09 (0.05) | 0.06 |
| COVID-19 patients or close contacts: yes (vs. no) | 0.06 (0.17) | 0.72 |
| Engaging in COVID-19-related work: yes (vs. no) | 0.12 (0.04) | 0.005 |
| Living in places severely affected by COVID-19: yes (vs. no) | 0.19 (0.05) | <0.001 |
| Quarantine: yes (vs. no) | 0.39 (0.04) | <0.001 |
| Increases in workload due to COVID-19: yes (vs. no) | 0.49 (0.04) | <0.001 |
| Unemployment due to COVID-19: yes (vs. no) | 0.43 (0.06) | <0.001 |
| Seeking psychological intervention: yes (vs. no) | 0.74 (0.06) | <0.001 |
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| Gender: male (vs. female) | 0.05 (0.01) | <0.001 |
| Age group: 18–39 (vs. ≥40) | 0.004 (0.014) | 0.77 |
| Living area: urban (vs. rural) | −0.02 (0.03) | 0.42 |
| Educational level: college school or higher (vs. lower than college school) | −0.02 (0.02) | 0.40 |
| Marital status: married (vs. unmarried) | −0.04 (0.02) | 0.004 |
| Family monthly income: 0–4999 (vs. ≥5000) | 0.03 (0.02) | 0.05 |
| COVID-19 patients or close contacts: yes (vs. no) | 0.20 (0.05) | <0.001 |
| Engaging in COVID-19-related work: yes (vs. no) | 0.08 (0.01) | <0.001 |
| Living in places severely affected by COVID-19: yes (vs. no) | 0.02 (0.02) | 0.13 |
| Quarantine: yes (vs. no) | −0.002 (0.014) | 0.90 |
| Increases in workload due to COVID-19: yes (vs. no) | 0.05 (0.01) | <0.001 |
| Unemployment due to COVID-19: yes (vs. no) | 0.05 (0.02) | 0.03 |
| Seeking psychological intervention: yes (vs. no) | 0.18 (0.02) | <0.001 |
Model fit statistics of latent growth mixture models with 1–7 trajectory classes *.
| Number of | AIC | BIC | aBIC | Entropy | Proportion for Latent Classes (%) | |
|---|---|---|---|---|---|---|
| 1 class | 263,472.560 | 263,558.820 | 263,523.863 | / | / | / |
| 2 classes | 262,405.602 | 262,515.388 | 262,470.896 | <0.001 | 0.601 | 52.0/48.0 |
| 3 classes | 260,174.652 | 260,307.963 | 260,253.938 | <0.001 | 0.774 | 55.4/38.3/6.3 |
| 4 classes | 258,529.998 | 258,686.835 | 258,623.276 | <0.001 | 0.783 | 44.4/31.2/18.1/6.3 |
| 5 classes | 256,087.821 | 256,268.183 | 256,195.091 | <0.001 | 0.850 | 41.5/31.1/18.0/6.8/2.7 |
| 6 classes | 255,050.510 | 255,254.397 | 255,171.771 | <0.001 | 0.849 | 32.3/31.9/18.9/7.5/6.8/2.7 |
| 7 classes | 254,905.117 | 255,132.530 | 255,040.370 | <0.001 | 0.803 | 35.2/26.3/18.0/6.9/6.8/4.2/2.7 |
* AIC = Akaike information criterion; BIC = Bayesian information criterion; LMR-LRT = Lo–Mendell–Rubin likelihood ratio test.
Figure 4(a) Latent trajectory classes of accessibility to DMHSs from before to one year after COVID-19 outbreak from the best fitting four-class LGMM. Higher scores indicate lower accessibility level (more difficult to access DMHSs). (b) Rate decrease for any mental health symptoms from initial COVID-19 peak (Survey 1) to post-COVID-19 period (Survey 3) stratified by four accessibility trajectory classes. Rate decrease was calculated by subtracting rate of any mental health problems in Survey 3 from the rate in Survey 1. Mental health symptoms are defined as depression, anxiety, or insomnia. Error bars indicate 95% confidence intervals.
Demographic and epidemic-related characteristics of the four latent trajectory classes.
| Factors | Lowest–Great Increase | Moderate Low–Slight Increase (N = 8347) | Moderate High–Slight Decrease | Highest–Great Decrease |
|---|---|---|---|---|
| Gender | ||||
| Male | 570 (47.9) b,c | 3899 (46.7) b,c | 1492 (43.8) | 2597 (44.3) |
| Female | 621 (52.1) | 4448 (53.3) | 1913 (56.2) | 3264 (55.7) |
| Age group (years) | ||||
| 18–39 | 804 (67.5) c | 5703 (68.3) c | 2269 (66.6) c | 3588 (61.2) |
| ≥40 | 387 (32.5) | 2644 (31.7) | 1136 (33.4) | 2273 (38.8) |
| Living area | ||||
| Urban | 1105 (92.8) | 7787 (93.3) c | 3191 (93.7) | 5516 (94.1) |
| Rural | 86 (7.2) | 560 (6.7) | 214 (6.3) | 345 (5.9) |
| Educational level | ||||
| College school or higher | 929 (78.0) a,b,c | 6961 (83.4) c | 2874 (84.4) c | 4725 (80.6) |
| Lower than college school | 262 (22.0) | 1386 (16.6) | 531 (15.6) | 1136 (19.4) |
| Marital status | ||||
| Married | 956 (80.3) | 6531 (78.2) | 2642 (77.6) c | 4654 (79.4) |
| Unmarried | 235 (19.7) | 1816 (21.8) | 763 (22.4) | 1207 (20.6) |
| Family income level (CNY) | ||||
| 0–4999 | 295 (24.8) b | 1896 (22.7) b | 695 (20.4) c | 1300 (22.2) |
| ≥5000 | 896 (75.2) | 6451 (77.3) | 2710 (79.6) | 4561 (77.8) |
| COVID-19 patients or close contacts | ||||
| Yes | 15 (1.3) | 139 (1.7) b | 39 (1.1) | 81 (1.4) |
| No | 1176 (98.7) | 8208 (98.3) | 3366 (98.9) | 5780 (98.6) |
| Engaged in work related to COVID-19 | ||||
| Yes | 474 (39.8) b,c | 3122 (37.4) | 1231 (36.2) | 2104 (35.9) |
| No | 717 (60.2) | 5225 (62.6) | 2174 (63.8) | 3757 (64.1) |
| Quarantine | ||||
| Yes | 492 (41.3) a,b,c | 2947 (35.3) c | 1190 (34.9) c | 1751 (29.9) |
| No | 699 (58.7) | 5400 (64.7) | 2215 (65.1) | 4110 (70.1) |
| Living in places severely affected by COVID-19 | ||||
| Yes | 347 (29.1) | 2578 (30.9) b,c | 933 (27.4) | 1598 (27.3) |
| No | 844 (70.9) | 5769 (69.1) | 2472 (72.6) | 4263 (72.7) |
| Increases in workload due to COVID-19 | ||||
| Yes | 613 (51.5) b,c | 4295 (51.5) b,c | 1527 (44.8) c | 2364 (40.3) |
| No | 578 (48.5) | 4052 (48.5) | 1878 (55.2) | 3497 (59.7) |
| Unemployment due to COVID-19 | ||||
| Yes | 215 (18.1) a,b,c | 1266 (15.2) b,c | 379 (11.1) | 698 (11.9) |
| No | 976 (81.9) | 7081 (84.8) | 3026 (88.9) | 5163 (88.1) |
| Seeking psychological consultation | ||||
| Yes | 272 (22.8) a,b,c | 1363 (16.3) b,c | 424 (12.5) c | 561 (9.6) |
| No | 919 (77.2) | 6984 (83.7) | 2981 (87.5) | 5300 (90.4) |
a: p < 0.05 for chi-squared tests for proportion differences compared with the “moderate low–slight increase” trajectory class; b: p < 0.05 for chi-squared tests for proportion differences compared with the “moderate high–slight decrease” trajectory class; c: p < 0.05 for chi-squared tests for proportion differences compared with the “highest–great decrease” trajectory class.
Association between trajectory class membership of perceived accessibility to DMHSs and long-term positives of mental health symptoms during the COVID-19 pandemic.
| Trajectory Class of | n/N (%) of Mental Health Symptoms from Survey 1 (N = 16,508) | n/N (%) of Mental Health Symptoms from Survey 2 (N = 12,788) | n/N (%) of Mental Health Symptoms from Survey 3 | AOR | Rate Decrease from Survey 1 to Survey 3 (% (95% CI)) | |
|---|---|---|---|---|---|---|
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| Lowest– great increase | 733/1186 (61.8) | 463/828 (55.9) | 342/736 (46.5) | 2.75 (2.47–3.05) | <0.001 | 15.3 (10.7–19.9) |
| Moderate low–slight increase | 3890/6907 (56.3) | 3070/5778 (53.1) | 2746/6024 (45.6) | 2.56 (2.41–2.72) | <0.001 | 10.7 (9.0–12.5) |
| Moderate high–slight decrease | 1479/3389 (43.6) | 946/2141 (44.2) | 830/2281 (36.4) | 1.79 (1.66–1.93) | <0.001 | 7.3 (4.6–9.9) |
| Highest–great decrease | 1414/5026 (28.1) | 1207/4041 (29.9) | 993/4134 (24.0) | Reference | Reference | 4.1 (2.3–5.9) |
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| Lowest– great increase | 536/1186 (45.2) | 379/828 (45.8) | 251/736 (34.1) | 2.92 (2.61–3.27) | <0.001 | 11.1 (6.5–15.6) |
| Moderate low–slight increase | 2609/6907 (37.8) | 2275/5778 (39.4) | 1999/6024 (33.2) | 2.52 (2.36–2.70) | <0.001 | 4.6 (3.0–6.3) |
| Moderate high–slight decrease | 902/3389 (26.6) | 670/2141 (31.3) | 562/2281 (24.6) | 1.77 (1.62–1.92) | <0.001 | 2.0 (−0.4–4.3) |
| Highest–great decrease | 786/5026 (15.6) | 792/4041 (19.6) | 632/4134 (15.3) | Reference | Reference | 0.4 (−1.2–1.9) |
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| Lowest– great increase | 603/1186 (50.8) | 363/828 (43.8) | 230/736 (31.3) | 3.01 (2.70–3.36) | <0.001 | 19.6 (15.1–24.0) |
| Moderate low–slight increase | 2996/6907 (43.4) | 2224/5778 (38.5) | 1847/6024 (30.7) | 2.64 (2.47–2.83) | <0.001 | 12.7 (11.1–14.4) |
| Moderate high–slight decrease | 1037/3389 (30.6) | 645/2141 (30.1) | 501/2281 (22.0) | 1.78 (1.64–1.94) | <0.001 | 8.6 (6.3–10.9) |
| Highest–great decrease | 937/5026 (18.6) | 758/4041 (18.8) | 551/4134 (13.3) | Reference | Reference | 5.3 (3.8–6.8) |
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| Lowest– great increase | 521/1186 (43.9) | 379/828 (45.8) | 272/736 (37.0) | 2.58 (2.31–2.88) | <0.001 | 7.0 (2.4–11.5) |
| Moderate low–slight increase | 2589/6907 (37.5) | 2408/5778 (41.7) | 2123/6024 (35.2) | 2.29 (2.14–2.45) | <0.001 | 2.2 (0.6–3.9) |
| Moderate high–slight decrease | 924/3389 (27.3) | 704/2141 (32.9) | 624/2281 (27.4) | 1.63 (1.50–1.78) | <0.001 | −0.1 (−2.5–2.3) |
| Highest–great decrease | 843/5026 (16.8) | 874/4041 (21.6) | 763/4134 (18.5) | Reference | Reference | −1.7 (−3.3–0.1) |
* Values are from multivariable generalized estimating equation models adjusted for gender, age group, living area, marital status, educational level, history of chronic diseases, history of mental disorders and family history of mental disorders, being COVID-19 patients or having family members with the disease, engaging in COVID-19-related work, quarantine experiences, living in places severely hit by COVID-19, seeking psychological consultation, increases in workload due to COVID-19, unemployment due to COVID-19, history of sleep problems, history of smoking, and history of alcohol abuse. Rate decrease is calculated by subtracting rate of mental health problems in Survey 3 from the rate in Survey 1.
Association between trajectory class of perceived accessibility to DMHSs and PHQ-9, GAD-7, and ISI scores during the COVID-19 pandemic.
| Trajectory Class of Perceived Accessibility to DMHSs during COVID-19 | Median (IQR) of Mental Health Scores from Survey 1 | Median (IQR) of Mental Health Scores from Survey 2 | Median (IQR) of Mental Health Scores from Survey 3 | B (SE) for Main Effect * | B (SE) for Interaction with Time * | ||
|---|---|---|---|---|---|---|---|
| Depression | |||||||
| Lowest–great increase | 3.00 (0.00–9.00) | 3.00 (0.00–10.00) | 0.00 (0.00–9.00) | 2.67 (0.12) | <0.001 | −0.05 (0.01) | <0.001 |
| Moderate low–slight increase | 2.00 (0.00–9.00) | 1.00 (0.00–9.00) | 0.00 (0.00–8.00) | 1.71 (0.06) | <0.001 | −0.03 (0.00) | <0.001 |
| Moderate high–slight decrease | 0.00 (0.00–5.00) | 0.00 (0.00–7.00) | 0.00 (0.00–4.00) | 0.84 (0.08) | <0.001 | −0.01 (0.00) | 0.10 |
| Highest–great decrease | 0.00 (0.00–1.00) | 0.00 (0.00–2.00) | 0.00 (0.00–1.00) | Reference | Reference | Reference | Reference |
| Anxiety | |||||||
| Lowest–great increase | 5.00 (0.00–9.00) | 2.00 (0.00–8.00) | 0.00 (0.00–7.00) | 2.61 (0.11) | <0.001 | −0.10 (0.01) | <0.001 |
| Moderate low–slight increase | 3.00 (0.00–7.00) | 1.00 (0.00–7.00) | 0.00 (0.00–7.00) | 1.71 (0.05) | <0.001 | −0.06 (0.00) | <0.001 |
| Moderate high–slight decrease | 1.00 (0.00–6.00) | 0.00 (0.00–6.00) | 0.00 (0.00–3.00) | 0.85 (0.07) | <0.001 | −0.03 (0.00) | <0.001 |
| Highest–great decrease | 0.00 (0.00–3.00) | 0.00 (0.00–2.00) | 0.00 (0.00–0.00) | Reference | Reference | Reference | Reference |
| Insomnia | |||||||
| Lowest–great increase | 6.00 (1.00–11.00) | 7.00 (2.00–12.00) | 4.00 (1.00–10.00) | 2.36 (0.12) | <0.001 | −0.05 (0.01) | <0.001 |
| Moderate low–slight increase | 5.00 (2.00–10.00) | 6.00 (2.00–11.00) | 5.00 (1.00–9.00) | 2.00 (0.07) | <0.001 | −0.04 (0.00) | <0.001 |
| Moderate high–slight decrease | 4.00 (1.00–8.00) | 4.00 (1.00–9.00) | 4.00 (1.00–8.00) | 1.09 (0.08) | <0.001 | −0.01 (0.01) | 0.23 |
| Highest–great decrease | 2.00 (0.00–6.00) | 2.00 (0.00–7.00) | 1.00 (0.00–6.00) | Reference | Reference | Reference | Reference |
* Values are from multivariable generalized mixed linear models adjusted for fixed effects for gender, age group, living area, marital status, educational level, history of chronic diseases, history of mental disorders and family history of mental disorders, being COVID-19 patients or close contacts, engaging in COVID-19-related work, quarantine experiences, living in places severely hit by COVID-19, seeking psychological consultation, increases in workload due to COVID-19, unemployment due to COVID-19, history of sleep problems, history of smoking, and history of alcohol and their interactions with time.