Literature DB >> 35315144

Commentary on Nower et al: Patterns in pathways: underlying comorbidities and the importance of assessment.

Anna E Goudriaan1,2,3, Marleen M de Waal1,2,3.   

Abstract

Entities:  

Keywords:  ADHD; PTSD; comorbidity; gambling disorder; impulsivity; trauma

Mesh:

Year:  2022        PMID: 35315144      PMCID: PMC9314676          DOI: 10.1111/add.15859

Source DB:  PubMed          Journal:  Addiction        ISSN: 0965-2140            Impact factor:   7.256


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Comorbidity in disordered gambling likely plays a substantial role in the second and third pathways of the revised pathways model of problem gambling. Therefore, screening for and treatment of post‐traumatic stress disorder (PTSD) and attention deficit hyperactivity disorder (ADHD) in disordered gambling has high relevance for clinical practice and research. Nower et al. [1] investigate a revision of their pathways model of problem gambling, based on a large sample of problem gamblers recruited from treatment centres, using latent class analysis to investigate the number and typology of classes. The Gambling Pathways Questionnaire (GPQ) used to classify subgroups of problem gamblers includes comorbid problems like depression, anxiety, childhood trauma, impulsivity and related factors. The differences in comorbidity reported in Table 2 and 5 of Nower et al.'s [1] study have important clinical and research implications. Higher prevalence of childhood trauma is mentioned in two of three pathways (pathway 2 and pathway 3); with an even higher prevalence of childhood trauma in pathway 2 compared to pathway 3 problem gamblers. This has important diagnostic and treatment implications for disordered gambling because higher childhood maltreatment implies a higher chance for PTSD and other comorbid psychopathology, like anxiety, depression or personality disorders. Specifically, in addiction treatment centres, the prevalence of PTSD is high, with an estimated 25% prevalence of current PTSD in persons with a substance use disorder (SUD) [2]. The scarce prevalence studies in disordered gamblers also indicate higher prevalence of PTSD in problem gamblers [3]. In the very recent review by Moore and Grubbs [4], a broad overlap is found in risk for traumatic life events and/or PTSD and comorbid gambling disorder, with a stronger effect of PTSD on severity of gambling disorder compared to traumatic events alone. In addition, both childhood trauma and PTSD are associated with higher psychopathological comorbidity and less favourable treatment outcomes in both gambling disorder and SUDs [4, 5]. Unfortunately, the diagnosis and treatment of PTSD in addictive disorders is understudied, as persons with SUDs are frequently excluded from trials [6] and left underdiagnosed. Although evidence of treatment of PTSD in SUDs is building [7, 8], research on PTSD in gambling disorder is still very limited. Because pathway 2 and 3 subgroups in the model concern problematic gamblers with a higher severity of gambling problems, it is likely that they have a smaller chance for positive response to treatment, and when PTSD is present, chances for a positive treatment response will be even lower. Importantly, pathways 2 and 3 comprise 56% of the sample, and it therefore, considers a more than substantial subgroup of problem gamblers. Because PTSD and trauma may lead to gambling as a way of coping with intrusive memories and/or negative feelings, screening for trauma and PTSD in gambling disorder is highly relevant. Reliable and short screening measures for PTSD in addictive disorders are available [9] and can be implemented to optimize treatment for disordered gamblers with PTSD and diminish chances for relapse. With regard to higher impulsivity, as reported in the third class within the pathway model of problem gambling, the connection with ADHD as a comorbid disorder to gambling disorder has relevance. The authors report that ADHD items were removed from the third pathway based on a prior study, in which an ADHD subscale of questions on ADHD was dropped from the factor model [10]. However, because the GPQ is a self‐report questionnaire and impulsivity and risk taking are the highest subscales in the third pathway model, it may well be that the ADHD subscale was dropped because it did not discern in items from the impulsivity and risk taking subscales. Like PTSD, ADHD is a highly frequent comorbidity in SUDs [11] and disordered gambling [12] and it is likely that when assessed, prevalence of ADHD in this third pathway will be higher. As ADHD in disordered gambling has been related to higher chances of persistence [13], it is equally important to screen and assess for ADHD and to address this frequent comorbid disorder in disordered gambling. Additionally, in other SUDs, ADHD has also been associated with higher PTSD prevalence [14]. In short, the findings reported by Nower et al. [1] demonstrate the need for the implementation of screening for PTSD and ADHD and subsequent diagnostic assessment and treatment for these comorbidities to optimize treatment prospects for problematic gamblers with these comorbidities.

DECLARATION OF INTERESTS

A.E.G. is editor of the journal, European Addiction Research. A.E.G. and M.W. have no financial or other relevant links to companies with an interest in the topic of this article.

AUTHOR CONTRIBUTIONS

Anna Goudriaan: Conceptualization. Marleen de Waal: Conceptualization.
  15 in total

Review 1.  Exclusion of participants based on substance use status: Findings from randomized controlled trials of treatments for PTSD.

Authors:  Robert F Leeman; Kathryn Hefner; Tessa Frohe; Adrian Murray; Robert A Rosenheck; Bradley V Watts; Mehmet Sofuoglu
Journal:  Behav Res Ther       Date:  2016-10-27

2.  Differential relationships of PTSD and childhood trauma with the course of substance use disorders.

Authors:  Michaela Mergler; Martin Driessen; Ursula Havemann-Reinecke; Dirk Wedekind; Christel Lüdecke; Martin Ohlmeier; Claudia Chodzinski; Sibylle Teunißen; Steffen Weirich; Ulrich Kemper; Walter Renner; Ingo Schäfer
Journal:  J Subst Abuse Treat       Date:  2018-07-21

3.  Treating posttraumatic stress disorder in substance use disorder patients with co-occurring posttraumatic stress disorder: study protocol for a randomized controlled trial to compare the effectiveness of different types and timings of treatment.

Authors:  Sera A Lortye; Joanne P Will; Loes A Marquenie; Anna E Goudriaan; Arnoud Arntz; Marleen M de Waal
Journal:  BMC Psychiatry       Date:  2021-09-07       Impact factor: 4.144

4.  Gambling behaviors and psychopathology related to Attention-Deficit/Hyperactivity Disorder (ADHD) in problem and non-problem adult gamblers.

Authors:  Melina Fatseas; Jean-Marc Alexandre; Jean-Luc Vénisse; Lucia Romo; Marc Valleur; David Magalon; Isabelle Chéreau-Boudet; Amandine Luquiens; Alice Guilleux; Gaëlle Challet-Bouju; Marie Grall-Bronnec
Journal:  Psychiatry Res       Date:  2016-03-14       Impact factor: 3.222

5.  Development and validation of the Gambling Pathways Questionnaire (GPQ).

Authors:  Lia Nower; Alex Blaszczynski
Journal:  Psychol Addict Behav       Date:  2016-12-12

6.  Gambling transitions among adult gamblers: A multi-state model using a Markovian approach applied to the JEU cohort.

Authors:  Mélanie Bruneau; Marie Grall-Bronnec; Jean-Luc Vénisse; Lucia Romo; Marc Valleur; David Magalon; Mélina Fatséas; Isabelle Chéreau-Boudet; Amandine Luquiens; Gaëlle Challet-Bouju; Jean-Benoit Hardouin
Journal:  Addict Behav       Date:  2016-01-22       Impact factor: 3.913

7.  DSM-IV pathological gambling in the National Comorbidity Survey Replication.

Authors:  R C Kessler; I Hwang; R LaBrie; M Petukhova; N A Sampson; K C Winters; H J Shaffer
Journal:  Psychol Med       Date:  2008-02-07       Impact factor: 7.723

8.  Clarifying gambling subtypes: the revised pathways model of problem gambling.

Authors:  Lia Nower; Alex Blaszczynski; Wen Li Anthony
Journal:  Addiction       Date:  2021-11-30       Impact factor: 7.256

9.  Commentary on Nower et al: Patterns in pathways: underlying comorbidities and the importance of assessment.

Authors:  Anna E Goudriaan; Marleen M de Waal
Journal:  Addiction       Date:  2022-03-21       Impact factor: 7.256

Review 10.  Psychological therapies for post-traumatic stress disorder and comorbid substance use disorder.

Authors:  Neil P Roberts; Pamela A Roberts; Neil Jones; Jonathan I Bisson
Journal:  Cochrane Database Syst Rev       Date:  2016-04-04
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  1 in total

1.  Commentary on Nower et al: Patterns in pathways: underlying comorbidities and the importance of assessment.

Authors:  Anna E Goudriaan; Marleen M de Waal
Journal:  Addiction       Date:  2022-03-21       Impact factor: 7.256

  1 in total

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