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Literature DB >> 3524339

Blood glucose control and diabetic complications.

Abstract

Two hypotheses have been advanced to explain the appearance of microvascular complications in diabetic patients with glycemic control. The genetic hypothesis suggests that the development of diabetic complications is genetically determined and independent of diabetic control, whereas the metabolic hypothesis suggests that long-term hyperglycemia causes the subsequent development of small-blood-vessel complications. We review data that either support or reject these hypotheses and suggest a third unifying hypothesis.

Entities: Chemical Disease Species

Mesh：

Substances：
Blood Glucose

Year: 1986 PMID： 3524339 DOI： 10.7326/0003-4819-105-2-254

Source DB: PubMed Journal: Ann Intern Med ISSN： 0003-4819 Impact factor: 25.391

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Cited

11 in total

1. Diabetes mellitus in the African-American population.

Authors: S A Peter
Journal: J Natl Med Assoc Date: 1989-02 Impact factor: 1.798

Review 2. [Normoglycemia as a therapy goal in diabetes treatment--concept and realization].

Authors: E G Siegel
Journal: Klin Wochenschr Date: 1990-03-16

3. Differential expression of fructosyllysine-specific receptors on monocytes and macrophages and possible pathophysiological significance.

Authors: R Brandt; C Landmesser; L Vogt; B Hehmke; R Hanschke; J Kasbohm; K Hartmann; B Jäger; S Krantz; D Michaelis
Journal: Diabetologia Date: 1996-10 Impact factor: 10.122

4. Glucose Control and Diabetic Complications: Is tight control of IDDM justified?

Authors: S Lubin
Journal: Can Fam Physician Date: 1991-06 Impact factor: 3.275

5. Basal insulin glargine and microvascular outcomes in dysglycaemic individuals: results of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial.

Authors: Richard E Gilbert; Johannes F E Mann; Markolf Hanefeld; Giatgen Spinas; Jackie Bosch; Salim Yusuf; Hertzel C Gerstein
Journal: Diabetologia Date: 2014-04-26 Impact factor: 10.122

10. Long-term instability of fasting plasma glucose predicts mortality in elderly NIDDM patients: the Verona Diabetes Study.

Authors: M Muggeo; G Verlato; E Bonora; F Ciani; P Moghetti; R Eastman; G Crepaldi; R de Marco
Journal: Diabetologia Date: 1995-06 Impact factor: 10.122

Blood glucose control and diabetic complications.

1. Diabetes mellitus in the African-American population.

Review 2. [Normoglycemia as a therapy goal in diabetes treatment--concept and realization].

3. Differential expression of fructosyllysine-specific receptors on monocytes and macrophages and possible pathophysiological significance.

4. Glucose Control and Diabetic Complications: Is tight control of IDDM justified?

5. Basal insulin glargine and microvascular outcomes in dysglycaemic individuals: results of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial.

6. Microvascular and acute complications in IDDM patients: the EURODIAB IDDM Complications Study.

7. Quality of life of pancreas transplant recipients.

8. Influences on control in diabetes mellitus: patient, doctor, practice, or delivery of care?

9. Long-term follow-up of diabetic retinopathy for up to 71 months after combined renal and pancreatic transplantation.

10. Long-term instability of fasting plasma glucose predicts mortality in elderly NIDDM patients: the Verona Diabetes Study.