Literature DB >> 35224655

Sexual function and disease progression in women with advanced cancer.

Luciana Silveira Campos1,2, Simone Pellin De Nardi3, Leo Francisco Limberger4, Jose Manoel Caldas5,6.   

Abstract

PURPOSE: To prospectively evaluate sexual function, body image, quality of life, and disease progression rates in women with advanced cancer.
METHODS: Sixty women staged III-IV breast, gynaecological, or colorectal cancer completed the Female Sexual Function Index (FSFI), the Body Image Scale, the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTQL), and the Beck Depression Inventory. Forty-three women (71.67%) completed the questionnaires again approximately 1 year later. The Wilcoxon test was used to compare the scores between the two evaluations. The participants were informed that they could attend additional consultations for symptom control or management of sexual difficulties if they wished.
RESULTS: Twenty-eight women showed disease progression (65.12%), and seven died. Twenty-one women remained sexually active (48.8%), all of whom were married/partnered. There was no difference in the FSFI score over time [28 (21.4-32.1) vs. 30.3 (24.2-33.3) P = 0.19]. The body image scores improved [6 (1-15) vs. 3 (0-10), P = 0.039], while the perceived global health status worsened [EORTQL: 75 (50-83.3) vs. 41.7 (25-50), P = 0.001].
CONCLUSIONS: Body image scores improved over time despite a concomitant decrease in the perceived global health status. A portion of women with recurrent or metastatic cancer remained interested in sexual intimacy. New studies are needed to understand the differences between the needs of women with advanced cancer who are vs. are not sexually active, for the development of more effective therapeutic approaches.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Advanced cancer; Body image; Cancer; Female sexuality; Quality of life; Sexual function

Mesh:

Year:  2022        PMID: 35224655     DOI: 10.1007/s00520-022-06797-x

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  24 in total

1.  Sexual functioning along the cancer continuum: focus group results from the Patient-Reported Outcomes Measurement Information System (PROMIS®).

Authors:  Kathryn E Flynn; Diana D Jeffery; Francis J Keefe; Laura S Porter; Rebecca A Shelby; Maria R Fawzy; Tracy K Gosselin; Bryce B Reeve; Kevin P Weinfurt
Journal:  Psychooncology       Date:  2010-03-30       Impact factor: 3.894

2.  Sexual morbidity in very long term survivors of vaginal and cervical cancer: a comparison to national norms.

Authors:  Stacy Tessler Lindau; Natalia Gavrilova; Diane Anderson
Journal:  Gynecol Oncol       Date:  2007-06-20       Impact factor: 5.482

3.  Body image problems in women with and without breast cancer 6-20 years after bilateral risk-reducing surgery - A prospective follow-up study.

Authors:  Lucy Bai; Brita Arver; Hemming Johansson; Kerstin Sandelin; Marie Wickman; Yvonne Brandberg
Journal:  Breast       Date:  2019-02-01       Impact factor: 4.380

4.  Sexual functioning among young adult cancer patients: A 2-year longitudinal study.

Authors:  Chiara Acquati; Brad J Zebrack; Anna C Faul; Leanne Embry; Christine Aguilar; Rebecca Block; Brandon Hayes-Lattin; David R Freyer; Steve Cole
Journal:  Cancer       Date:  2017-11-17       Impact factor: 6.860

5.  Prevalence and possible predictors of sexual dysfunction and self-reported needs related to the sexual life of advanced cancer patients.

Authors:  Charlotte Broegger Bond; Pernille Tine Jensen; Mogens Groenvold; Anna Thit Johnsen
Journal:  Acta Oncol       Date:  2019-02-06       Impact factor: 4.089

6.  Psychometric validation of the Female Sexual Function Index (FSFI) in cancer survivors.

Authors:  Raymond E Baser; Yuelin Li; Jeanne Carter
Journal:  Cancer       Date:  2012-02-22       Impact factor: 6.860

7.  Let's talk about sex: risky business for cancer and palliative care clinicians.

Authors:  Amanda J Hordern; Annette F Street
Journal:  Contemp Nurse       Date:  2007-12       Impact factor: 1.787

8.  Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer.

Authors:  Pernille T Jensen; Mogens Groenvold; Marianne C Klee; Ingrid Thranov; Morten A Petersen; David Machin
Journal:  Int J Radiat Oncol Biol Phys       Date:  2003-07-15       Impact factor: 7.038

9.  Sexual activity and quality of life in patients after treatment for breast and ovarian cancer.

Authors:  Sebastian Mayer; Severine Iborra; Donata Grimm; Lisa Steinsiek; Sven Mahner; Michaela Bossart; Linn Woelber; Pit Jacob Voss; Gerald Gitsch; Annette Hasenburg
Journal:  Arch Gynecol Obstet       Date:  2018-11-01       Impact factor: 2.344

10.  Sexuality after a cancer diagnosis: A population-based study.

Authors:  Sarah E Jackson; Jane Wardle; Andrew Steptoe; Abigail Fisher
Journal:  Cancer       Date:  2016-08-16       Impact factor: 6.860

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  1 in total

Review 1.  Sexual Dysfunction in Women with Cancer: A Systematic Review of Longitudinal Studies.

Authors:  Thais Sousa Rodrigues Guedes; Marcello Barbosa Otoni Gonçalves Guedes; Rebeca de Castro Santana; José Felipe Costa da Silva; Amanda Almeida Gomes Dantas; Mirari Ochandorena-Acha; Marc Terradas-Monllor; Javier Jerez-Roig; Dyego Leandro Bezerra de Souza
Journal:  Int J Environ Res Public Health       Date:  2022-09-21       Impact factor: 4.614

  1 in total

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