| Literature DB >> 35152414 |
Oleguer Plana-Ripoll1,2, Natalie C Momen1, John J McGrath1,3,4, Theresa Wimberley1,5,6,7, Isabell Brikell1,8, Diana Schendel1,5,6,7,9, Malene Thygesen1,5,6,7, Nanna Weye1, Carsten B Pedersen1,5,6,7,10, Ole Mors5,6,11, Preben B Mortensen1,5,6,7, Søren Dalsgaard1,5,6,7.
Abstract
OBJECTIVE: Information on mental disorders over time is critical for documenting changes in population burden, and aiding understanding of potential causal and non-causal factors. The aim of this study was to provide temporal changes in the sex- and age-specific incidence rates (IR) of mental disorders diagnosed in Danish hospitals during five decades and investigate whether such changes may be attributable to changes in administrative reporting practice.Entities:
Keywords: incidence; mental disorders; register-based epidemiology; time trends
Mesh:
Year: 2022 PMID: 35152414 PMCID: PMC9305516 DOI: 10.1111/acps.13410
Source DB: PubMed Journal: Acta Psychiatr Scand ISSN: 0001-690X Impact factor: 7.734
Number of cases and incidence rate per 10,000 person‐years of each mental disorder in Denmark including all contacts, in four time periods
| Mental disorder | Number of cases | Incidence rate per 10,000 person‐years | ||||||
|---|---|---|---|---|---|---|---|---|
| 1970–1984 | 1985–1994 | 1995–2004 | 2005–2016 | 1970–1984 | 1985–1994 | 1995–2004 | 2005–2016 | |
| Any mental disorder | 209,128 | 85,212 | 221,400 | 350,784 | 28·88 (28·87–28·88) | 18·04 (18·03–18·04) | 47·17 (47·16–47·18) | 63·02 (63·00–63·03) |
| Organic disorders | 47,575 | 18,964 | 48,123 | 60,045 | 13.18 (13.17–13.18) | 7.26 (7.26–7.27) | 17.64 (17.64–17.65) | 17.46 (17.45–17.47) |
| Alzheimer's disease | 22,069 | 9456 | 14,889 | 25,969 | 6.09 (6.09–6.09) | 3.60 (3.60–3.61) | 5.42 (5.42–5.43) | 7.50 (7.50–7.50) |
| Vascular dementia | 9492 | 2922 | 9547 | 9387 | 2.62 (2.61–2.62) | 1.11 (1.11–1.11) | 3.47 (3.47–3.47) | 2.70 (2.70–2.71) |
| Substance use disorder | 61,079 | 25,857 | 39,829 | 51,117 | 9.55 (9.55–9.55) | 5.96 (5.96–5.96) | 9.31 (9.31–9.31) | 9.71 (9.71–9.72) |
| Alcohol use disorder | 47,026 | 21,144 | 30,100 | 31,526 | 7.34 (7.34–7.34) | 4.86 (4.86–4.86) | 7.01 (7.01–7.01) | 5.96 (5.96–5.96) |
| Cannabis use disorder | 2784 | 1994 | 5934 | 16,197 | 0.43 (0.43–0.43) | 0.45 (0.45–0.45) | 1.37 (1.37–1.37) | 3.03 (3.03–3.03) |
| Schizophrenia spectrum disorder | 36,462 | 21,354 | 24,856 | 34,450 | 5.69 (5.69–5.69) | 4.91 (4.91–4.91) | 5.79 (5.79–5.79) | 6.51 (6.51–6.52) |
| Schizophrenia | 12,840 | 6953 | 12,535 | 15,729 | 2.00 (2.00–2.00) | 1.59 (1.59–1.59) | 2.90 (2.90–2.90) | 2.95 (2.95–2.96) |
| Schizoaffective disorders | 3435 | 1983 | 2675 | 2,037 | 0.53 (0.53–0.53) | 0.45 (0.45–0.45) | 0.62 (0.62–0.62) | 0.38 (0.38–0.38) |
| Mood disorders | 67,657 | 22,995 | 70,142 | 121,267 | 10.60 (10.59–10.60) | 5.31 (5.31–5.31) | 16.44 (16.44–16.45) | 23.32 (23.32–23.33) |
| Bipolar disorder | 9874 | 5218 | 8677 | 15,464 | 1.54 (1.53–1.54) | 1.19 (1.19–1.19) | 2.00 (2.00–2.01) | 2.90 (2.90–2.90) |
| Recurrent depression | 17,781 | 8168 | 27,463 | 53,996 | 2.77 (2.77–2.77) | 1.87 (1.87–1.87) | 6.36 (6.36–6.36) | 10.19 (10.19–10.19) |
| Single and recurrent depression | 58,221 | 19,180 | 63,803 | 111,441 | 9.11 (9.11–9.11) | 4.42 (4.42–4.42) | 14.92 (14.91–14.92) | 21.36 (21.36–21.37) |
| Anxiety disorder | 56,351 | 23,394 | 89,169 | 173,501 | 8.10 (8.10–8.11) | 5.07 (5.07–5.07) | 19.47 (19.46–19.47) | 31.38 (31.38–31.39) |
| Obsessive‐compulsive disorder | 949 | 371 | 4012 | 14,525 | 0.14 (0.14–0.14) | 0.08 (0.08–0.08) | 0.86 (0.86–0.86) | 2.53 (2.53–2.53) |
| Eating disorders | 819 | 1061 | 7209 | 14,708 | 0.11 (0.11–0.11) | 0.22 (0.22–0.22) | 1.46 (1.46–1.46) | 2.44 (2.44–2.44) |
| Anorexia nervosa | 708 | 654 | 2042 | 4,387 | 0.10 (0.10–0.10) | 0.13 (0.13–0.13) | 0.41 (0.41–0.41) | 0.73 (0.73–0.73) |
| Personality disorders | 63,108 | 20,468 | 32,731 | 40,582 | 9.88 (9.87–9.88) | 4.73 (4.73–4.73) | 7.66 (7.66–7.66) | 7.72 (7.72–7.72) |
| Personality disorders (borderline‐type) | 1406 | 2470 | 6521 | 11,830 | 0.22 (0.22–0.22) | 0.56 (0.56–0.56) | 1.50 (1.50–1.50) | 2.22 (2.21–2.22) |
| Antisocial personality disorder | 11,984 | 1326 | 2191 | 2,019 | 1.86 (1.86–1.86) | 0.30 (0.30–0.30) | 0.51 (0.51–0.51) | 0.38 (0.38–0.38) |
| Intellectual disability | 1766 | 1410 | 7485 | 14,697 | 0.24 (0.24–0.24) | 0.29 (0.29–0.29) | 1.52 (1.52–1.52) | 2.44 (2.43–2.44) |
| Developmental disorders | 528 | 695 | 6081 | 27,364 | 0.07 (0.07–0.07) | 0.14 (0.14–0.14) | 1.23 (1.23–1.23) | 4.54 (4.54–4.54) |
| Childhood autism | 134 | 209 | 1605 | 8,056 | 0.02 (0.02–0.02) | 0.04 (0.04–0.04) | 0.32 (0.32–0.32) | 1.33 (1.33–1.33) |
| Behavioral disorders | 4792 | 3733 | 15,742 | 65,973 | 0.65 (0.65–0.65) | 0.76 (0.76–0.76) | 3.20 (3.19–3.20) | 11.00 (11.00–11.01) |
| ADHD | 769 | 571 | 4492 | 45,955 | 0.10 (0.10–0.10) | 0.12 (0.12–0.12) | 0.91 (0.91–0.91) | 7.63 (7.63–7.63) |
FIGURE 1Age‐specific incidence rates of mental disorders from 1970 to 2016.
FIGURE 2Changes in the distribution of age at first diagnosis of mental disorders from 1970 to 2016.
FIGURE 3Time trends in the proportional age distribution of incident cases of groups of mental disorders, by sex and in seven periods of calendar years between 1970 and 2016.