Literature DB >> 3514670

Somatic gene therapy. Current status and future prospects.

D A Williams, S H Orkin.   

Abstract

Mesh:

Year:  1986        PMID: 3514670      PMCID: PMC424438          DOI: 10.1172/JCI112403

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  24 in total

1.  A direct measurement of the radiation sensitivity of normal mouse bone marrow cells.

Authors:  J E TILL; E A McCULLOCH
Journal:  Radiat Res       Date:  1961-02       Impact factor: 2.841

2.  Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene.

Authors:  A D Miller; M F Law; I M Verma
Journal:  Mol Cell Biol       Date:  1985-03       Impact factor: 4.272

3.  Negative regulation of viral enhancers in undifferentiated embryonic stem cells.

Authors:  C M Gorman; P W Rigby; D P Lane
Journal:  Cell       Date:  1985-09       Impact factor: 41.582

4.  Synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a SV40 beta-globin recombinant genome.

Authors:  R C Mulligan; B H Howard; P Berg
Journal:  Nature       Date:  1979-01-11       Impact factor: 49.962

5.  Construction and applications of a highly transmissible murine retrovirus shuttle vector.

Authors:  C L Cepko; B E Roberts; R C Mulligan
Journal:  Cell       Date:  1984-07       Impact factor: 41.582

6.  Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice.

Authors:  J E Dick; M C Magli; D Huszar; R A Phillips; A Bernstein
Journal:  Cell       Date:  1985-08       Impact factor: 41.582

7.  Gene transfer in intact animals.

Authors:  M J Cline; H Stang; K Mercola; L Morse; R Ruprecht; J Brown; W Salser
Journal:  Nature       Date:  1980-04-03       Impact factor: 49.962

8.  Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

Authors:  H Potter; L Weir; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

9.  Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes.

Authors:  R D Palmiter; R L Brinster; R E Hammer; M E Trumbauer; M G Rosenfeld; N C Birnberg; R M Evans
Journal:  Nature       Date:  1982-12-16       Impact factor: 49.962

10.  Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring.

Authors:  R D Palmiter; H Y Chen; R L Brinster
Journal:  Cell       Date:  1982-06       Impact factor: 41.582

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  12 in total

1.  Clinical application of somatic gene therapy in inborn errors of metabolism.

Authors:  F D Ledley
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

2.  Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.

Authors:  B Lim; J F Apperley; S H Orkin; D A Williams
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

Review 3.  Germ-line gene therapy and the clinical ethos of medical genetics.

Authors:  G Fowler; E T Juengst; B K Zimmerman
Journal:  Theor Med       Date:  1989-06

4.  Different mechanisms account for the relative resistance of KG-1 and HL-60 cell lines to retrovirus infection.

Authors:  S J Collins
Journal:  J Virol       Date:  1988-11       Impact factor: 5.103

5.  Retroviral gene transfer into primary hepatocytes: implications for genetic therapy of liver-specific functions.

Authors:  F D Ledley; G J Darlington; T Hahn; S L Woo
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

Review 6.  Molecular pathology of single gene disorders.

Authors:  D J Weatherall
Journal:  J Clin Pathol       Date:  1987-09       Impact factor: 3.411

Review 7.  A defective HIV-1 vector for gene transfer to human lymphocytes.

Authors:  C Parolin; J Sodroski
Journal:  J Mol Med (Berl)       Date:  1995-06       Impact factor: 4.599

8.  Retrovirus-mediated gene transfer of human adenosine deaminase: expression of functional enzyme in murine hematopoietic stem cells in vivo.

Authors:  B Lim; D A Williams; S H Orkin
Journal:  Mol Cell Biol       Date:  1987-10       Impact factor: 4.272

9.  Expression of the human beta-globin gene following retroviral-mediated transfer into multipotential hematopoietic progenitors of mice.

Authors:  S Karlsson; D M Bodine; L Perry; T Papayannopoulou; A W Nienhuis
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

Review 10.  Retroviruses as genetic tools to isolate transcriptionally active chromosomal regions.

Authors:  H von Melchner; H E Ruley
Journal:  Environ Health Perspect       Date:  1990-08       Impact factor: 9.031

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