| Literature DB >> 35133641 |
Davide Bizzoca1,2, Andrea Piazzolla3, Giuseppe Solarino4, Lorenzo Moretti4, Biagio Moretti4.
Abstract
PURPOSE: To assess the self-image perception and the Quality-of-Life (QoL) in female adolescents, with Lenke 1C scoliosis curves, treated with selective versus non-selective posterior spinal instrumentation and fusion (PSF).Entities:
Keywords: Adolescent idiopathic scoliosis; Posterior spinal instrumentation and fusion; Quality-of-life profile for spinal deformities (QLPSD); Revised scoliosis research society-22 questionnaire (SRS-22R); Selective fusion; Spinal appearance questionnaire (SAQ)
Mesh:
Year: 2022 PMID: 35133641 PMCID: PMC9187554 DOI: 10.1007/s43390-022-00479-8
Source DB: PubMed Journal: Spine Deform ISSN: 2212-134X
Demographic, radiographic and operative data for selective (Group A) and non-selective fusion (Group B) cohorts
| Group A | Group B | ||
|---|---|---|---|
| Patients ( | 80 | 77 | – |
| Age | |||
| Mean ± SD | 16.5 ± 2.1 | 17.1 ± 2.8 | .64+ |
| Range | 13–19 | 14–19 | – |
| BMI (Kg/m2) | |||
| Mean ± SD | 21.6 ± 1.8 | 21.9 ± 1.5 | .443+ |
| Risser 4, | 21 (70%) | 17 (62.96%) | .031§ |
| Risser 5, | 9 (30%) | 10 (37.34%) | .022 § |
| Pre-op coronal Cobb angle (mean ± SD) | |||
| Main Thoracic curve | 63.3 ± 12.9 | 61.7 ± 14.2 | .354+ |
| Lumbar curve | 32.6 ± 10.6 | 39.3 ± 15.3 | .001+* |
| Pre-op MT curve flexibility (mean ± SD) | |||
| Mean ± SD | 27.4 ± 16.5 | 28.2 ± 17.4 | .135 |
| Pre-op lumber curve flexibility (mean ± SD) | |||
| Mean ± SD | 39.2 ± 18.7 | 40.5 ± 16.5 | .363 |
| Pre-op MT AVT (mean ± SD) | |||
| Mean ± SD | 44.4 ± 4.6 | 43.2 ± 8.3 | .098+ |
| Pre-op L AVT (mean ± SD) | |||
| Mean ± SD | 27.5 ± 3.6 | 32.4 ± 4.5 | .005+* |
| Pre-op MT/L AVT | |||
| Mean | 1.7 | 1.3 | .001* |
| Total operative time (min) | |||
| Mean ± SD | 304.7 ± 78.4 | 421.2 ± 101.7 | .0034*+ |
| Instrumented vertebrae | |||
| Mean ± SD | 7.7 ± 1.8 | 11.6 ± 3.9 | .011*+ |
| Hospital staying | |||
| Mean ± SD | 6.9 ± 2.5 | 8.1 ± 3.6 | .088+ |
| Post-op Coronal Cobb Angle (Mean ± SD) | |||
| Main thoracic curve | 14.3 ± 6.6 | 16.4 ± 9.9 | .432 |
| Lumbar curve | 11.4 ± 5.4 | 13.9 ± 7.7 | .521 |
MT AVT main thoracic apical vertical translation, L AVT lumbar apical vertical translation, MT/L AVT main thoracic/lumbar apical vertical translation
*Significant p value (Unpaired t test; p < 0.05)
+Unpaired t test
§Chi-square test
Patient-reported outcome measures for selective (Group A) and non-selective fusion (Group B) cohorts: p values for the differences within groups at 24-month follow-up, compared with baseline (Paired t test)
| Group A (selective fusion) | Group B (non-selective fusion) | |||||
|---|---|---|---|---|---|---|
| Baseline | 24-month FU | Baseline | 24-month FU | |||
| SRS-22R Total | 3.3 ± 0.5 | 3.6 ± 0.5 | .114 | 3.3 ± 0.57 | 3.7 ± 0.5 | .0965 |
| SRS-22R Function | 3.9 ± 0.4 | 3.7 ± 0.6 | .553 | 3.8 ± 0.6 | 2.2 ± 0.5 | .002* |
| SRS-22R Pain | 3.7 ± 0.8 | 4.1 ± .0.4 | .223 | 3.9 ± 0.9 | 4.3 ± 0.7 | .446 |
| SRS-22R Self-image | 2.2 ± 0.6 | 2.5 ± 0.6 | .721 | 2.3 ± 0.5 | 3.9 ± 0.4 | .005* |
| SRS-22R Mental health | 2.7 ± 0.7 | 4.1 ± 0.5 | . | 2.5 ± 0.4 | 4.2 ± 0.8 | .003* |
| SRS-22R Satisfaction | NA | 2.5 ± 0.8 | - | NA | 3.9 ± 0.4 | - |
| QLPSD Total | 48.1 ± 8.8 | 44.9 ± 9.9 | .082 | 49.8 ± 8.7 | 46.1 ± 7.7 | .082 |
| QLPSD psychosocial functioning | 1.9 ± 0.5 | 1.8 ± 1.1 | .234 | 1.9 ± 0.6 | 1.8 ± 0.5 | .545 |
| QLPSD sleep disturbances | 2.3 ± 0.7 | 2.2 ± 0.7 | .345 | 2.4 ± 0.5 | 2.3 ± 0.9 | .442 |
| QLPSD back pain | 2.8 ± 0.8 | 2.6 ± 0.8 | .226 | 2.7 ± 0.8 | 2.6 ± 0.4 | .653 |
| QLPSD body image | 2.4 ± 0.6 | 2.2 ± 0.9 | .321 | 2.5 ± 0.5 | 1.3 ± 0.7 | .001* |
| QLPSD back flexibility | 2.1 ± 0.5 | 2.3 ± 0.5 | .101 | 2.1 ± 0.4 | 3.1 ± 0.8 | .004* |
| SAQ Total | 50.3 ± 9.6 | 48.5 ± 8.8 | .115 | 49.6 ± 10.6 | 30.3 ± 9.2 | .001* |
| SAQ Appearance | 32.9 ± 8.5 | 31.5 ± 7.5 | .454 | 32.5 ± 7.2 | 20.2 ± 8.4 | .001* |
| SAQ Expectations | 18.2 ± 7.6 | 16.4 ± 4.4 | .331 | 17.9 ± 9.7 | 9.8 ± 3.2 | .001* |
SD standard deviation, FU follow-up, NA not available
*Significant p value (p < 0.05)
Patient-reported outcome measures for selective (Group A) and non-selective fusion (Group B) cohorts: p values for the differences between groups at 24-month follow-up (Unpaired t test)
| Group A | Group B | ||
|---|---|---|---|
| SRS-22R total | 3.6 ± 0.5 | 3.7 ± 0.5 | .64 |
| SRS-22R function | 3.7 ± 0.7 | 2.2 ± 0.5 | .006* |
| SRS-22R pain | 4.1 ± .0.4 | 4.3 ± 0.7 | .114 |
| SRS-22R self-image | 2.5 ± 0.6 | 3.9 ± 0.4 | .012* |
| SRS-22R mental health | 4.1 ± 0.5 | 4.2 ± 0.7 | .784 |
| SRS-22R satisfaction | 2.5 ± 0.8 | 3.8 ± 0.4 | .033* |
| QLPSD total | 44.9 ± 9.9 | 46.1 ± 7.6 | .221 |
| QLPSD psychosocial functioning | 1.8 ± 1.1 | 1.8 ± 0.5 | .654 |
| QLPSD sleep disturbances | 2.2 ± 0.7 | 2.3 ± 0.9 | .344 |
| QLPSD back pain | 2.6 ± 0.8 | 2.6 ± 0.4 | .437 |
| QLPSD body image | 2.3 ± 0.9 | 1.3 ± 0.7 | .005* |
| QLPSD back flexibility | 2.3 ± 0.5 | 3.1 ± 0.8 | .007* |
| SAQ total | 48.5 ± 8.8 | 30.3 ± 9.2 | .002* |
| SAQ appearance | 31.5 ± 7.5 | 20.2 ± 8.3 | .001* |
| SAQ expectations | 16.4 ± 4.4 | 9.9 ± 3.2 | .001* |
*Significant p value (p < 0.05)
Fig. 1SRS-22 domains mean scores at 24-month follow-up in both groups. *p < 0.05 (unpaired t test)
Fig. 2QLPSD domains mean scores at 24-month follow-up in both groups. *p < 0.05 (unpaired t test)
Fig. 3SAQ items mean scores at 24-month follow-up in both groups. *p < 0.05 (unpaired t test)
Pearson’s Correlation Test between the number of instrumented levels and Patient-Reported Outcome Measures at 24-month follow-up (only significant correlations have been reported)
| 24-months follow-up | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| SRS-22R | QLPSD | SAQ | SAQ | SAQ | ||||||
Number of instrumented levels | 0.7 | .004* | − 0.8 | .001* | − 0.8 | .001* | − 0.8 | .001* | − 0.6 | .03* |
*Significant p value (p < 0.05)
Pearson’s Correlation Coefficient at 24-month follow-up between mean SAQ Appearance score, mean SRS-22R domains and mean QLPSD domain scores in patients undergoing selective thoracic fusion (Group A)
| SRS-22R Function | SRS-22R Pain | SRS-22R Self-image | SRS-22R Mental health | QLPSD psychosocial functioning | QLPSD sleep disturbances | QLPSD back pain | QLPSD body image | QLPSD back flexibility | |
|---|---|---|---|---|---|---|---|---|---|
SAQ appearence | -.213 | -.316 | − .721* | − .812* | .673* | .243 | .227 | .785* | .115 |
*Significant p value (p < 0.05)