Literature DB >> 35112163

Factors affecting outcomes of second intent healing of nasal defects after Mohs micrographic surgery.

David Nam-Woo Kim1, Nour Kibbi2, Sean R Christensen3, David J Leffell3, Kathleen C Suozzi4,5.   

Abstract

Reconstruction of nasal defects secondary to Mohs micrographic surgery (MMS) presents particular challenges related to the complex topography, skin quality, tissue laxity, and functional and aesthetic concerns of the region. Factors affecting outcomes resulting from second intent healing (SIH) on the nose have not been well described. The purpose of the study was to identify factors impacting outcomes of SIH for nasal tumors following MMS. Retrospective analysis was performed of all nasal lesions treated with MMS followed by SIH from a single surgical center over a 1.5-year period. Ninety-six cases were included. Chart review was performed, and data were collected including age, gender, nasal site, tumor type, defect size, depth, and number of MMS stages. Pre- and post-operative follow-up photographs were available for all cases. All five authors evaluated the photographs using the modified Manchester scar scale. Analysis was then conducted to identify features associated with good outcomes. Of the 96 tumors, 39 lesions (40.6%) were located on the nasal tip (including supratip), 32 (33.3%) on the ala/alar groove, 17 (17.7%) on the sidewall, and 8 (8.3%) on the dorsum. The average defect size was 0.83 cm2 (diameter of 1.06 cm ± 0.4). Defect diameter and defect depth were the factors that significantly impacted scar outcome (p < 0.001) in multivariate analysis. No significant functional deficits were reported. This retrospective study suggests that nasal defects with area less than 0.83 cm2 (or 1.06 cm diameter) and depth of defect not extending beyond the superficial fat healed well by SIH regardless of location on the nose.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Basal cell carcinoma; Mohs micrographic surgery; Non-melanoma skin cancer; Second intention healing; Squamous cell carcinoma; Wound healing

Year:  2022        PMID: 35112163     DOI: 10.1007/s00403-021-02306-y

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN: 0340-3696            Impact factor:   3.017


  9 in total

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2.  Overview of nasal soft tissue reconstruction: keeping it simple.

Authors:  William M Weathers; John C Koshy; Erik M Wolfswinkel; James F Thornton
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3.  Secondary Intention Healing After Mohs Surgical Excision as an Alternative to Surgical Repair: Evaluation of Wound Characteristics and Esthetic Outcomes.

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4.  Rhinophyma: review of pathophysiology and treatment.

Authors:  D K Hoasjoe; F J Stucker
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Review 5.  Cellular mechanisms of skin repair in humans and other mammals.

Authors:  Laure Rittié
Journal:  J Cell Commun Signal       Date:  2016-05-12       Impact factor: 5.782

6.  A prospective evaluation of the incidence of complications associated with Mohs micrographic surgery.

Authors:  Jonathan L Cook; Jennifer B Perone
Journal:  Arch Dermatol       Date:  2003-02

7.  The value of healing by secondary intention for sizeable defects of the face.

Authors:  R M Goldwyn; F Rueckert
Journal:  Arch Surg       Date:  1977-03

Review 8.  Skin cancer in skin of color.

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9.  Regional variation in wound contraction of mohs surgery defects allowed to heal by second intention.

Authors:  Kevin J Mott; David P Clark; Linda Sue Stelljes
Journal:  Dermatol Surg       Date:  2003-07       Impact factor: 3.398

  9 in total

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