Accuracy of virtual monochromatic images generated by the decomposition of photoelectric absorption and Compton scatter in dual-energy computed tomography.

The decomposition of the linear attenuation coefficient into photoelectric absorption and Compton scattering provides virtual monochromatic images (VMIs). The accuracy of the computed tomography (CT) number of VMI, which is obtained by decomposing the linear attenuation coefficient into photoelectric absorption and Compton scattering, was verified in the energy range of 40-200 keV. The possibility of improving the accuracy of CT numbers by using pre-energy-calibrated images as input was also investigated. The VMIs were generated in two groups of images: (i) dual-energy scanned images and (ii) high- and low-energy images generated by two-material decomposition (i.e., pre-energy-calibrated images). The object for analysis was solid iodine rods inserted in the center of the multi-energy CT phantom. The VMIs were generated from the dual-energy scanned images and pre-energy-calibrated images, and the theoretical and measured CT numbers of solid iodine rods were compared. Furthermore, the absolute error (AE) and relative error (RE) were calculated. With both images, the accuracy of the CT numbers was extremely high for regions close to the high- and low-tube-voltage X-ray energy or the high and low energy of the input images. By using the pre-energy-calibrated images, the maximum AE was reduced from 133 to 96 HU at an energy of 40 keV. Similarly, the maximum RE was reduced from 325 to 50% at an energy of 200 keV. The pre-energy-calibrated images reduced the overall error of the CT numbers and controlled the energy region where accurate CT numbers could be obtained.