Literature DB >> 35088243

Plasma neurofilament light chain levels are associated with depressive and anxiety symptoms in Parkinson's disease.

Weifang Yin1, Yongyun Zhu1, Baiyuan Yang2, Fang Wang1, Kangfu Yin1, Chuanbin Zhou1, Hui Ren3, Xinglong Yang4.   

Abstract

The present study aimed to explore the association of plasma neurofilament light chain (NfL) levels with depression and anxiety in Parkinson's disease (PD). This prospective study enrolled 116 patients with PD and 38 healthy controls, and found plasma NfL levels were higher in patients with depression or anxiety than in those without these symptoms. Binary logistic regression identified NfL concentration as an independent predictor of depression and anxiety in PD. In conclusion, elevated plasma NfL may be associated with severity of depression and anxiety in PD patients and may serve as a diagnostic biomarker of PD with moderate to severe depression or anxiety.
© 2022. Fondazione Società Italiana di Neurologia.

Entities:  

Keywords:  Anxiety; Depression; HAMA; HAMD-17; NfL; Parkinson’s disease

Mesh：

Substances：

Year:  2022        PMID： 35088243     DOI： 10.1007/s10072-022-05914-2

Source DB:  PubMed          Journal:  Neurol Sci        ISSN： 1590-1874            Impact factor:   3.307


  10 in total

Review 1.  MDS clinical diagnostic criteria for Parkinson's disease.

Authors:  Ronald B Postuma; Daniela Berg; Matthew Stern; Werner Poewe; C Warren Olanow; Wolfgang Oertel; José Obeso; Kenneth Marek; Irene Litvan; Anthony E Lang; Glenda Halliday; Christopher G Goetz; Thomas Gasser; Bruno Dubois; Piu Chan; Bastiaan R Bloem; Charles H Adler; Günther Deuschl
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2.  The effect of depression on motor function and disease severity of Parkinson's disease.

Authors:  Spiridon Papapetropoulos; John Ellul; Andreas A Argyriou; Elisabeth Chroni; Nicoletta P Lekka
Journal:  Clin Neurol Neurosurg       Date:  2005-09-16       Impact factor: 1.876

3.  Blood NfL: A biomarker for disease severity and progression in Parkinson disease.

Authors:  Chin-Hsien Lin; Cheng-Hsuan Li; Kai-Chien Yang; Fang-Ju Lin; Chau-Chung Wu; Jen-Jie Chieh; Ming-Jang Chiu
Journal:  Neurology       Date:  2019-08-16       Impact factor: 9.910

4.  Depression in patients with Parkinson's disease: impact on functioning.

Authors:  Florindo Stella; Claudio E M Banzato; Elizabeth M A Barasnevicius Quagliato; Maura Aparecida Viana
Journal:  J Neurol Sci       Date:  2008-06-27       Impact factor: 3.181

5.  Decreased sleep quality in Parkinson's patients is associated with higher anxiety and depression prevalence and severity, and correlates with pain intensity and quality.

Authors:  Abdul Qayyum Rana; Abdul Rehman M Qureshi; Yazan Shamli Oghli; Yosuf Saqib; Bilal Mohammed; Zainab Sarfraz; Ruqqiyah Rana
Journal:  Neurol Res       Date:  2018-04-17       Impact factor: 2.448

6.  Prevalence of Depression and Anxiety in Parkinson Disease and Impact on Quality of Life: A Community-Based Study in Spain.

Authors:  Fany Chuquilín-Arista; Tania Álvarez-Avellón; Manuel Menéndez-González
Journal:  J Geriatr Psychiatry Neurol       Date:  2019-10-09       Impact factor: 2.680

Review 7.  Depression in neurodegenerative diseases: Common mechanisms and current treatment options.

Authors:  Ciaran P C Galts; Luis E B Bettio; David C Jewett; Charles C Yang; Patricia S Brocardo; Ana Lucia S Rodrigues; Jonathan S Thacker; Joana Gil-Mohapel
Journal:  Neurosci Biobehav Rev       Date:  2019-04-15       Impact factor: 8.989

8.  Levels of plasma neurofilament light chain and cognitive function in patients with Alzheimer or Parkinson disease.

Authors:  Yung-Shuan Lin; Wei-Ju Lee; Shuu-Jiun Wang; Jong-Ling Fuh
Journal:  Sci Rep       Date:  2018-11-26       Impact factor: 4.379

Review 9.  Depression, anxiety, and apathy in Parkinson's disease: insights from neuroimaging studies.

Authors:  M-C Wen; L L Chan; L C S Tan; E K Tan
Journal:  Eur J Neurol       Date:  2016-06       Impact factor: 6.089

10.  Plasma nesfatin-1 level is associated with severity of depression in Chinese depressive patients.

Authors:  Min-Min Xiao; Jiang-Bo Li; Lan-Lan Jiang; Hui Shao; Bao-Long Wang
Journal:  BMC Psychiatry       Date:  2018-04-03       Impact factor: 3.630
  10 in total
  1 in total

1.  Adaptive structural changes in the motor cortex and white matter in Parkinson's disease.

Authors:  YuHong Fu; Liche Zhou; Hongyun Li; Jen-Hsiang T Hsiao; Binyin Li; Onur Tanglay; Andrew D Auwyang; Elinor Wang; Jieyao Feng; Woojin S Kim; Jun Liu; Glenda M Halliday
Journal:  Acta Neuropathol       Date:  2022-09-02       Impact factor: 15.887
  1 in total

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