Fany Chuquilín-Arista1,2, Tania Álvarez-Avellón3, Manuel Menéndez-González4,5,6. 1. Community and Family Medicine, Health Area VII, Asturias, Spain. 2. Health Science Research, University of Valladolid, Spain. 3. Department of Psychology, Universidad de Oviedo, Asturias, Spain. 4. Department of Neurology, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, Spain. 5. Instituto de Salud del Principado de Asturias (ISPA), Oviedo, Asturias, Spain. 6. Department of Morphology and Cell Biology, Universidad de Oviedo, Asturias, Spain.
Abstract
BACKGROUND: Identifying neuropsychiatric disorders is essential for prompt treatment to reduce morbidity. Among these disorders, anxiety and depression have been frequently associated with Parkinson disease (PD), particularly among elderly population. OBJECTIVE: The objective of this study is to determine the prevalence of anxiety and depression in a series of community-based PD cases in Spain, their relationship with different clinical and sociodemographic characteristics, and quality of life. METHODS: This is an observational, descriptive, survey-based study with 95 community-based patients with PD diagnosis at different disease stages. Anxiety and depression were assessed using the State-Trait Anxiety Inventory and the Beck Depression Inventory II, respectively. Quality of life was assessed using the Parkinson's Disease Questionnaire 39. RESULTS: The prevalence of depression and anxiety was 32.63% and 68.42%, respectively. Concomitant depression and anxiety were observed in 31.58% of patients. Patients with longer than 10 years' PD duration had an increased risk of depression. We found a relationship between the presence of anxiety, depression, and the patient's quality of life. CONCLUSIONS: Depression is present in one-third and anxiety in two-thirds of PD cases in community settings in Spain. Depression and anxiety have a very negative impact on quality of life in PD. Both anxiety and depression are independent from sociodemographic characteristics, patient's comorbidities, or antiparkinsonian treatments; presenting as intrinsic symptoms in PD.
BACKGROUND: Identifying neuropsychiatric disorders is essential for prompt treatment to reduce morbidity. Among these disorders, anxiety and depression have been frequently associated with Parkinson disease (PD), particularly among elderly population. OBJECTIVE: The objective of this study is to determine the prevalence of anxiety and depression in a series of community-based PD cases in Spain, their relationship with different clinical and sociodemographic characteristics, and quality of life. METHODS: This is an observational, descriptive, survey-based study with 95 community-based patients with PD diagnosis at different disease stages. Anxiety and depression were assessed using the State-Trait Anxiety Inventory and the Beck Depression Inventory II, respectively. Quality of life was assessed using the Parkinson's Disease Questionnaire 39. RESULTS: The prevalence of depression and anxiety was 32.63% and 68.42%, respectively. Concomitant depression and anxiety were observed in 31.58% of patients. Patients with longer than 10 years' PD duration had an increased risk of depression. We found a relationship between the presence of anxiety, depression, and the patient's quality of life. CONCLUSIONS:Depression is present in one-third and anxiety in two-thirds of PD cases in community settings in Spain. Depression and anxiety have a very negative impact on quality of life in PD. Both anxiety and depression are independent from sociodemographic characteristics, patient's comorbidities, or antiparkinsonian treatments; presenting as intrinsic symptoms in PD.
Entities:
Keywords:
Parkinson disease; anxiety; depression; quality of life
Authors: Jessie S Gibson; Joseph L Flanigan; James T Patrie; W Alex Dalrymple; Madaline B Harrison Journal: Neurol Sci Date: 2022-10-11 Impact factor: 3.830
Authors: Maria de Los Angeles Robinson-Agramonte; Elena Noris García; Jarasca Fraga Guerra; Yamilé Vega Hurtado; Nicola Antonucci; Neomar Semprún-Hernández; Stephen Schultz; Dario Siniscalco Journal: Int J Mol Sci Date: 2022-03-11 Impact factor: 5.923