| Literature DB >> 35032014 |
Deborah de Castro Moreira1, Francisco Ferreira Duarte Junior2, José Renato Pattaro Júnior2, Fernando Américo Jorge2, Fabiana Dos Santos Rando2, Mateus Vaillant Thomazella3, Mayra Marinho Presibella4, Irina Nastassja Riediger4, Maria Aparecida Fernandez2, Dennis Armando Bertolini2.
Abstract
Phylogenetic analysis carried out in several Brazilian regions shows the circulation of the Asian and East-Central South African (ECSA) Chikungunya virus (CHIKV) genotypes in the country. Until now, there are no genetic studies about CHIKV strains circulating in the South region. In this study, we sequenced 5 new partial sequences of the CHIKV Envelope 1 gene from strains detected in Paraná state during the years 2016-2017. Maximum likelihood and neighbor-joining trees grouped all sequences in Brazilian branches within ECSA genotype and comparative analysis did not show E1-A226V mutation. However, we identified E1-K211T amino acid substitution in a sample demonstrating the dispersion of mutant strains in the country.Entities:
Keywords: Chikungunya; Paraná; Sequence analysis
Mesh:
Year: 2022 PMID: 35032014 PMCID: PMC9151936 DOI: 10.1007/s42770-022-00680-x
Source DB: PubMed Journal: Braz J Microbiol ISSN: 1517-8382 Impact factor: 2.214