| Literature DB >> 3501604 |
G A Peyman1, B Khoobehi, M Tawakol, J A Schulman, H A Mortada, H Alkan, R Fiscella.
Abstract
The authors determined the intravitreal clearance of liposome-encapsulated ganciclovir. Liposome-encapsulated ganciclovir (84.1 micrograms/0.1 ml) was injected into the vitreous cavity of New Zealand rabbits, which were killed at 24 hours and 7, 14, and 28 days after injection. Total ganciclovir concentrations in the vitreous, up to 28 days, were higher than ID50 (50% inhibitory dose) for different clinical and laboratory strains of viruses belonging to the herpes simplex family.Entities:
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Year: 1987 PMID： 3501604 DOI： 10.1097/00006982-198707040-00005
Source DB: PubMed Journal: Retina ISSN： 0275-004X Impact factor: 4.256