Literature DB >> 3265937

Intravitreal liposome-encapsulated drugs: a preliminary human report.

G A Peyman1, H C Charles, K R Liu, B Khoobehi, M Niesman.   

Abstract

Intravitreal liposome-encapsulated antibiotics and antiviral drugs were used in patients with acute toxoplasmosis retinochoroiditis, presumed propionibacterium acne endophthalmitis after cataract surgery, and presumed cytomegalovirus retinitis associated with AIDS. A single intravitreal dose was effective in the treatment of all the conditions. Intravitreal liposomes may prove to be an advantageous drug delivery system for the treatment of chronic intraocular inflammatory disorders.

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Year:  1988        PMID： 3265937     DOI： 10.1007/bf00130002

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN： 0165-5701            Impact factor:   2.031


  18 in total

1.  Clearance and localization of intravitreal liposomes in the aphakic vitrectomized eye.

Authors:  W H Stern; T D Heath; G P Lewis; C J Guerin; P A Erickson; N G Lopez; K L Hong
Journal:  Invest Ophthalmol Vis Sci       Date:  1987-05       Impact factor: 4.799

2.  Bacterial endophthalmitis. Treatment with intraocular injection of gentamicin and dexamethasone.

Authors:  G A Peyman; R Herbst
Journal:  Arch Ophthalmol       Date:  1974-05

3.  Intravitreal injection of methicillin for treatment of endophthalmitis.

Authors:  M J Daily; G A Peyman; G Fishman
Journal:  Am J Ophthalmol       Date:  1973-09       Impact factor: 5.258

4.  5-fluorouracil: new applications in complicated retinal detachment for an established antimetabolite.

Authors:  M Blumenkranz; E Hernandez; A Ophir; E W Norton
Journal:  Ophthalmology       Date:  1984-02       Impact factor: 12.079

5.  Intravitreal administration of antibiotic in the treatment of bacterial endophthalmitis. III. Consensus.

Authors:  J Baum; G A Peyman; M Barza
Journal:  Surv Ophthalmol       Date:  1982 Jan-Feb       Impact factor: 6.048

6.  Reduced toxicity of liposome-associated amphotericin B injected intravitreally in rabbits.

Authors:  C Tremblay; M Barza; F Szoka; M Lahav; J Baum
Journal:  Invest Ophthalmol Vis Sci       Date:  1985-05       Impact factor: 4.799

7.  Ocular toxicity of fluorouracil after vitrectomy.

Authors:  W H Stern; C J Guerin; P A Erickson; G P Lewis; D H Anderson; S K Fisher
Journal:  Am J Ophthalmol       Date:  1983-07       Impact factor: 5.258

8.  Effect of size and lipid composition on the pharmacokinetics of intravitreal liposomes.

Authors:  M Barza; M Stuart; F Szoka
Journal:  Invest Ophthalmol Vis Sci       Date:  1987-05       Impact factor: 4.799

9.  Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

Authors:  F Szoka; D Papahadjopoulos
Journal:  Proc Natl Acad Sci U S A       Date:  1978-09       Impact factor: 11.205

10.  Intravitreal liposome-encapsulated trifluorothymidine in a rabbit model.

Authors:  K R Liu; G A Peyman; B Khoobehi; H Alkan; R Fiscella
Journal:  Ophthalmology       Date:  1987-09       Impact factor: 12.079
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  8 in total

Review 1.  Liposomes as delivery systems in the prevention and treatment of infectious diseases.

Authors:  J J Bergers; T L ten Hagen; E W van Etten; I A Bakker-Woudenberg
Journal:  Pharm World Sci       Date:  1995-01-27

2.  Safety of intravitreal clindamycin in albino rabbit eyes.

Authors:  Zohar Habot-Wilner; Orit Mazza; Jonathan Shahar; Amir Massarweh; Irit Mann; Anat Loewenstein; Ido Perlman
Journal:  Doc Ophthalmol       Date:  2017-07-25       Impact factor: 2.379

3.  Ocular safety of Intravitreal Clindamycin Hydrochloride Released by PLGA Implants.

Authors:  Gabriella M Fernandes-Cunha; Silvia Ligório Fialho; Gisele Rodrigues da Silva; Armando Silva-Cunha; Min Zhao; Francine Behar-Cohen
Journal:  Pharm Res       Date:  2017-02-21       Impact factor: 4.200

4.  Liposomally-entrapped ganciclovir for the treatment of cytomegalovirus retinitis in AIDS patients. Eperimental toxicity and pharmacokinetics, and clinical trial.

Authors:  M Díaz-Llopis; M J Martos; E España; M Cervera; A O Vila; A Navea; F J Molina; F J Romero
Journal:  Doc Ophthalmol       Date:  1992       Impact factor: 2.379

Review 5.  Versatility of aminoglycosides and prospects for their future.

Authors:  Sergei B Vakulenko; Shahriar Mobashery
Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

Review 6.  Sustained-release ophthalmic drug delivery systems for treatment of macular disorders: present and future applications.

Authors:  Blake A Booth; Lori Vidal Denham; Saadallah Bouhanik; Jean T Jacob; James M Hill
Journal:  Drugs Aging       Date:  2007       Impact factor: 3.923

7.  Design and development of intraocular polymeric implant systems for long-term controlled-release of clindamycin phosphate for toxoplasmic retinochoroiditis.

Authors:  Lana Tamaddon; S Abolfazl Mostafavi; Reza Karkhane; Mohammad Riazi-Esfahani; Farid Abedin Dorkoosh; Morteza Rafiee-Tehrani
Journal:  Adv Biomed Res       Date:  2015-01-30

8.  Thermoanalytical characterization of clindamycin-loaded intravitreal implants prepared by hot melt extrusion.

Authors:  Lana Tamaddon; Seyed Abolfazl Mostafavi; Reza Karkhane; Mohammad Riazi-Esfahani; Farid Abedin Dorkoosh; Morteza Rafiee-Tehrani
Journal:  Adv Biomed Res       Date:  2015-07-27
  8 in total

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