Literature DB >> 34993308

Cardiometabolic Parameters Among Transgender Adolescent Males on Testosterone Therapy and Body Mass Index-Matched Cisgender Females.

Anna Valentine1,2, Natalie Nokoff2, Andrea Bonny3,4, Gayathri Chelvakumar3,4, Justin Indyk3,5, Scott Leibowitz3,6, Leena Nahata3,5,7.   

Abstract

Limited data are available on changes in metabolic parameters in transgender youth on testosterone therapy in comparison with cisgender females. Data from 42 transgender males on testosterone therapy were retrospectively analyzed. Body mass index (BMI) and lipid profile changes were compared with BMI-matched females. There was a significant increase in BMI over time in the transgender males as compared with the cisgender females, and a decrease in high-density lipoprotein in the transgender males after starting testosterone therapy. Longitudinal prospective studies with cisgender controls are needed to better define effects of testosterone therapy in adolescents. Copyright 2021, Mary Ann Liebert, Inc., publishers.

Entities:  

Keywords:  BMI; adolescent; cholesterol; testosterone; transgender

Year:  2021        PMID: 34993308      PMCID: PMC8664095          DOI: 10.1089/trgh.2020.0052

Source DB:  PubMed          Journal:  Transgend Health        ISSN: 2380-193X


  20 in total

1.  Prevalence of Obesity Among Adults and Youth: United States, 2011-2014.

Authors:  Cynthia L Ogden; Margaret D Carroll; Cheryl D Fryar; Katherine M Flegal
Journal:  NCHS Data Brief       Date:  2015-11

2.  Suicidality Disparities Between Transgender and Cisgender Adolescents.

Authors:  Brian C Thoma; Rachel H Salk; Sophia Choukas-Bradley; Tina R Goldstein; Michele D Levine; Michael P Marshal
Journal:  Pediatrics       Date:  2019-10-14       Impact factor: 7.124

3.  Characteristics of Referrals for Gender Dysphoria Over a 13-Year Period.

Authors:  Melinda Chen; John Fuqua; Erica A Eugster
Journal:  J Adolesc Health       Date:  2016-03       Impact factor: 5.012

Review 4.  Effects of testosterone therapy on BMI, blood pressure, and laboratory profile of transgender men: a systematic review.

Authors:  I Velho; T M Fighera; P K Ziegelmann; P M Spritzer
Journal:  Andrology       Date:  2017-07-14       Impact factor: 3.842

5.  Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline.

Authors:  Wylie C Hembree; Peggy T Cohen-Kettenis; Louis Gooren; Sabine E Hannema; Walter J Meyer; M Hassan Murad; Stephen M Rosenthal; Joshua D Safer; Vin Tangpricha; Guy G T'Sjoen
Journal:  J Clin Endocrinol Metab       Date:  2017-11-01       Impact factor: 5.958

6.  2000 CDC Growth Charts for the United States: methods and development.

Authors:  Robert J Kuczmarski; Cynthia L Ogden; Shumei S Guo; Laurence M Grummer-Strawn; Katherine M Flegal; Zuguo Mei; Rong Wei; Lester R Curtin; Alex F Roche; Clifford L Johnson
Journal:  Vital Health Stat 11       Date:  2002-05

7.  Cross-sex hormone therapy in transgender persons affects total body weight, body fat and lean body mass: a meta-analysis.

Authors:  M Klaver; M J H J Dekker; R de Mutsert; J W R Twisk; M den Heijer
Journal:  Andrologia       Date:  2016-08-29       Impact factor: 2.775

Review 8.  The Mental Health of Transgender Youth: Advances in Understanding.

Authors:  Maureen D Connolly; Marcus J Zervos; Charles J Barone; Christine C Johnson; Christine L M Joseph
Journal:  J Adolesc Health       Date:  2016-08-17       Impact factor: 5.012

9.  Physiologic Response to Gender-Affirming Hormones Among Transgender Youth.

Authors:  Johanna Olson-Kennedy; Vivian Okonta; Leslie F Clark; Marvin Belzer
Journal:  J Adolesc Health       Date:  2017-10-19       Impact factor: 7.830

10.  Transgender Identity and Experiences of Violence Victimization, Substance Use, Suicide Risk, and Sexual Risk Behaviors Among High School Students - 19 States and Large Urban School Districts, 2017.

Authors:  Michelle M Johns; Richard Lowry; Jack Andrzejewski; Lisa C Barrios; Zewditu Demissie; Timothy McManus; Catherine N Rasberry; Leah Robin; J Michael Underwood
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2019-01-25       Impact factor: 17.586

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  2 in total

1.  Multicenter Analysis of Cardiometabolic-related Diagnoses in Transgender and Gender-Diverse Youth: A PEDSnet Study.

Authors:  Anna Valentine; Shanlee Davis; Anna Furniss; Nadia Dowshen; Anne E Kazak; Christopher Lewis; Danielle F Loeb; Leena Nahata; Laura Pyle; Lisa M Schilling; Gina M Sequeira; Natalie Nokoff
Journal:  J Clin Endocrinol Metab       Date:  2022-09-28       Impact factor: 6.134

Review 2.  Care of Gender Diverse Youth with Obesity.

Authors:  Dominique R Williams; Eileen Chaves; Nicole E Greenwood; Jennifer Kushner; Gayathri Chelvakumar; Shanna E Swaringen; Scott F Leibowitz
Journal:  Curr Obes Rep       Date:  2022-09-02
  2 in total

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