Yuexin Wang1,2, Siman Sun1,2,3, Shanshan Wei1,2, Yining Guo1,2, Tingyi Wu1,2, Xuemin Li4,5. 1. Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. 2. Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China. 3. Peking University Health Science Center, Beijing, China. 4. Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. 13911254862@163.com. 5. Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China. 13911254862@163.com.
Abstract
PURPOSE: To investigate the three-dimensional topographic changes of anterior chamber depth (ACD) following cataract surgery. METHODS: Seventy-eight eyes with age-related cataract undergoing phacoemulsification and intraocular lens (IOL) implantation were retrospectively enrolled. Participants were evaluated with Pentacam for ACD topography before and approximately four weeks after the surgery. The absolute changes of ACD (AACD) and the relative changes of ACD (RACD) topography were calculated, and three-dimensional topographic contours were plotted. The influence of age, gender, distance to corneal apex (DCA), temporal-nasal and superior-inferior on AACD and RACD was analyzed. RESULTS: Both AACD and RACD were negatively correlated with the DCA (p < 0.001; p < 0.001) and positively correlated with the age at all DCA (p < 0.05 for all the analyses). Significantly greater AACD and RACD were observed in female subjects (p < 0.05, respectively, at all DCA). AACD was significantly larger in the temporal compared with the nasal region (p < 0.001) and at the superior compared with the inferior region (p < 0.001), but not RACD. Subgroup analysis indicated that the significant difference of the AACD between the temporal and nasal regions was manifested at the DCA of more than 6 mm (p < 0.001), and the difference between the superior and inferior regions was observed at 2 mm DCA for both AACD (p < 0.001) and RACD (p = 0.001). CONCLUSIONS: We depicted the topographic changes of ACD following cataract surgery and found that it was significantly influenced by age, gender, DCA and quadrant location. The research provided the basis for including postoperative ACD topography prediction before cataract surgery in the future.
PURPOSE: To investigate the three-dimensional topographic changes of anterior chamber depth (ACD) following cataract surgery. METHODS: Seventy-eight eyes with age-related cataract undergoing phacoemulsification and intraocular lens (IOL) implantation were retrospectively enrolled. Participants were evaluated with Pentacam for ACD topography before and approximately four weeks after the surgery. The absolute changes of ACD (AACD) and the relative changes of ACD (RACD) topography were calculated, and three-dimensional topographic contours were plotted. The influence of age, gender, distance to corneal apex (DCA), temporal-nasal and superior-inferior on AACD and RACD was analyzed. RESULTS: Both AACD and RACD were negatively correlated with the DCA (p < 0.001; p < 0.001) and positively correlated with the age at all DCA (p < 0.05 for all the analyses). Significantly greater AACD and RACD were observed in female subjects (p < 0.05, respectively, at all DCA). AACD was significantly larger in the temporal compared with the nasal region (p < 0.001) and at the superior compared with the inferior region (p < 0.001), but not RACD. Subgroup analysis indicated that the significant difference of the AACD between the temporal and nasal regions was manifested at the DCA of more than 6 mm (p < 0.001), and the difference between the superior and inferior regions was observed at 2 mm DCA for both AACD (p < 0.001) and RACD (p = 0.001). CONCLUSIONS: We depicted the topographic changes of ACD following cataract surgery and found that it was significantly influenced by age, gender, DCA and quadrant location. The research provided the basis for including postoperative ACD topography prediction before cataract surgery in the future.
Authors: Seth R Flaxman; Rupert R A Bourne; Serge Resnikoff; Peter Ackland; Tasanee Braithwaite; Maria V Cicinelli; Aditi Das; Jost B Jonas; Jill Keeffe; John H Kempen; Janet Leasher; Hans Limburg; Kovin Naidoo; Konrad Pesudovs; Alex Silvester; Gretchen A Stevens; Nina Tahhan; Tien Y Wong; Hugh R Taylor Journal: Lancet Glob Health Date: 2017-10-11 Impact factor: 26.763