Literature DB >> 34928168

Acute haemorrhage rate in 28,000 Out-of-Hours CT heads.

Katherine C Hocking1, Catriona R Wright1, Utku Alhun1, Frances Hughes1, Vartan J Balian1, Mohammed A K Kabuli2, George Tse1, Maria McGonnell1, Annu Chopra1, Nikhil Kotnis1, Daniel Connelly1, Samer Alabed1.   

Abstract

OBJECTIVES: The aim of this paper is to assess the acute haemorrhage rate in patients who had CT head investigation out-of-hours with and without trauma and compare the rates of haemorrhage between warfarin and DOACs, at a busy teritary teaching hospital.
METHODS: All CT heads performed between January 2008 and December 2019 were identified from the radiology information system (RIS) at Sheffield Teaching Hospitals (STH), with the requesting information being available from January 2015. The clinical information was assessed for the mention of trauma or anticoagulation, and the reports were categorised into acute and non-acute findings.
RESULTS: Between 2008 and 2019 the number of scans increased by 63%, with scans performed out of hours increasing by 278%. Between 2015 and 2019, the incidence of acute ICH was similar over the 5-year period, averaging at 6.9% and ranging from 6.1 to 7.6%. The rate of detection of acute haemorrhage following trauma was greater in those not anticoagulated (6.8%), compared with patients on anticoagulants such as warfarin (5.2%) or DOACs (2.8%).
CONCLUSIONS: Over 12 years, there has been a significant increase in the number of CT heads performed at STH. The rate of ICH has remained steady over the last 5 years indicating a justified increase in imaging demand. However, the incidence of ICH in patients prescribed DOACs is lower than the general population and those on warfarin. ADVANCES IN KNOWLEDGE: This finding in a large centre should prompt discussion of the risk of bleeding with DOACs in relation to CT head imaging guidelines.

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Year:  2022        PMID: 34928168      PMCID: PMC8822576          DOI: 10.1259/bjr.20210580

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  16 in total

1.  Acute ICH in patients identified as being treated with either warfarin or direct-acting oral anticoagulant agents (DOACs) from a radiology perspective; a cross-sectional observational of 2359 emergency CT head studies.

Authors:  L Salimin; F Barber; M Limbada; O Khalil; S Williams
Journal:  Clin Radiol       Date:  2019-12-24       Impact factor: 2.350

2.  Head injuries: a study evaluating the impact of the NICE head injury guidelines.

Authors:  Z Hassan; M Smith; S Littlewood; O Bouamra; D Hughes; C Biggin; K Amos; A D Mendelow; F Lecky
Journal:  Emerg Med J       Date:  2005-12       Impact factor: 2.740

3.  Preference for direct oral anticoagulants in patients treated with vitamin K antagonists for venous thromboembolism.

Authors:  M P A Brekelmans; M Kappelhof; P T Nieuwkerk; M Nierman; H R Buller; M Coppens
Journal:  Neth J Med       Date:  2017-03       Impact factor: 1.422

Review 4.  Are the novel anticoagulants better than warfarin for patients with atrial fibrillation?

Authors:  Colleen M Hanley; Peter R Kowey
Journal:  J Thorac Dis       Date:  2015-02       Impact factor: 2.895

5.  Trends in the prescription of novel oral anticoagulants in UK primary care.

Authors:  Simone Y Loo; Sophie Dell'Aniello; Laetitia Huiart; Christel Renoux
Journal:  Br J Clin Pharmacol       Date:  2017-05-04       Impact factor: 4.335

6.  Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial.

Authors:  Leslie Kobayashi; Galinos Barmparas; Patrick Bosarge; Carlos V Brown; Marko Bukur; Matthew M Carrick; Richard D Catalano; Jan Holly-Nicolas; Kenji Inaba; Stephen Kaminski; Amanda L Klein; Tammy Kopelman; Eric J Ley; Ericca M Martinez; Forrest O Moore; Jason Murry; Raminder Nirula; Douglas Paul; Jacob Quick; Omar Rivera; Martin Schreiber; Raul Coimbra
Journal:  J Trauma Acute Care Surg       Date:  2017-05       Impact factor: 3.313

7.  Audit of the change in the on-call practices in neuroradiology and factors affecting it.

Authors:  Nitin Mukerji; Dorothy Wallace; Dipayan Mitra
Journal:  BMC Med Imaging       Date:  2006-10-16       Impact factor: 1.930

8.  Should all anticoagulated patients with head injury receive a CT scan? Decision-analysis modelling of an observational cohort.

Authors:  Maxine Kuczawski; Matt Stevenson; Steve Goodacre; M Dawn Teare; Shammi Ramlakhan; Francis Morris; Suzanne Mason
Journal:  BMJ Open       Date:  2016-12-13       Impact factor: 2.692

Review 9.  Trends in the epidemiology of cardiovascular disease in the UK.

Authors:  Prachi Bhatnagar; Kremlin Wickramasinghe; Elizabeth Wilkins; Nick Townsend
Journal:  Heart       Date:  2016-08-22       Impact factor: 5.994

10.  The Anticoagulated trauma patient in the age of the direct oral anticoagulants: a Canadian perspective.

Authors:  Brendan Wood; Barto Nascimento; Sandro Rizoli; Michelle Sholzberg; Amanda McFarlan; Andrea Phillips; Alun D Ackery
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2017-08-02       Impact factor: 2.953

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