Literature DB >> 3488230

Release of calcitonin gene-related peptide from a human medullary carcinoma of the thyroid in vitro.

M Ohashi, N Fujio, H Ibayashi.   

Abstract

The secretion of human calcitonin gene-related peptide was examined in perifusates of medullary carcinoma of the thyroid with a sensitive radioreceptor assay. Calcitonin gene-related peptide was released after the addition of calcium (25-100 mM), in a dose-dependent manner. The results indicate that human medullary carcinomas of the thyroid secrete the calcitonin gene-related peptide as well as calcitonin.

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Year:  1986        PMID： 3488230     DOI： 10.1007/BF01941541

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary.

Authors:  F A Tschopp; H Henke; J B Petermann; P H Tobler; R Janzer; T Hökfelt; J M Lundberg; C Cuello; J A Fischer
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

2.  Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide.

Authors:  S G Amara; J L Arriza; S E Leff; L W Swanson; R M Evans; M G Rosenfeld
Journal:  Science       Date:  1985-09-13       Impact factor: 47.728

3.  Calcitonin gene-related peptide: potent vasodilator and major product of calcitonin gene.

Authors:  S I Girgis; D W Macdonald; J C Stevenson; P J Bevis; C Lynch; S J Wimalawansa; C H Self; H R Morris; I MacIntyre
Journal:  Lancet       Date:  1985-07-06       Impact factor: 79.321

4.  Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products.

Authors:  S G Amara; V Jonas; M G Rosenfeld; E S Ong; R M Evans
Journal:  Nature       Date:  1982-07-15       Impact factor: 49.962

5.  Isolation and characterization of human calcitonin gene-related peptide.

Authors:  H R Morris; M Panico; T Etienne; J Tippins; S I Girgis; I MacIntyre
Journal:  Nature       Date:  1984 Apr 19-25       Impact factor: 49.962

6.  Circulating somatostatin concentrations in healthy and non-insulin-dependent (type II) diabetic subjects.

Authors:  J M Conlon; A J McCulloch; K G Alberti
Journal:  Diabetes       Date:  1983-08       Impact factor: 9.461

7.  Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing.

Authors:  M G Rosenfeld; J J Mermod; S G Amara; L W Swanson; P E Sawchenko; J Rivier; W W Vale; R M Evans
Journal:  Nature       Date:  1983 Jul 14-20       Impact factor: 49.962

8.  Calcitonin gene-related peptide is a potent vasodilator.

Authors:  S D Brain; T J Williams; J R Tippins; H R Morris; I MacIntyre
Journal:  Nature       Date:  1985 Jan 3-9       Impact factor: 49.962
  8 in total

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