Literature DB >> 348581

Inhibition by somatostatin (growth-hormone release-inhibiting hormone, GH-RIH) of gastric acid and pepsin and G-cell release of gastrin.

A A Barros D'sa, S R Bloom, J H Baron.   

Abstract

Somatostatin (cyclic growth-hormone release-inhibiting hormone--GH-RIH) was infused into dogs with gastric fistulae. Somatostatin inhibited gastric acid response to four gastric stimulants--insulin, food, histamine, and pentagastrin. Histamine- and pentagastrin-stimulated pepsins were inhibited similarly to inhibition of acid. Somatostatin inhibited the gastrin response to insulin and food.

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Year:  1978        PMID： 348581      PMCID： PMC1411924          DOI： 10.1136/gut.19.4.315

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  21 in total

1.  A micro-method for measuring glucose using the autoanalyzer and glucose-oxidase.

Authors:  C WINCEY; V MARKS
Journal:  J Clin Pathol       Date:  1961-09       Impact factor: 3.411

2.  Current problems in the measurement of gastrin release. A reproducible measure of physiological gastrin release.

Authors:  R C Russel; S R Bloom; L P Fielding; M G Bryant
Journal:  Postgrad Med J       Date:  1976-10       Impact factor: 2.401

3.  Immunohistochemical evidence for the localization of somatostatin--like immunoreactivity in a cell population of the pancreatic islets.

Authors:  R Luft; S Efendic; T Hökfelt; O Johansson; A Arimura
Journal:  Med Biol       Date:  1974-12

4.  Effects of growth-hormone release-inhibiting hormone on circulating glucagon, insulin, and growth hormone in normal, diabetic, acromegalic, and hypopituitary patients.

Authors:  C H Mortimer; W M Tunbridge; D Carr; L Yeomans; T Lind; D H Coy; S R Bloom; A Kastin; C N Mallinson; G M Besser; A V Schally; R Hall
Journal:  Lancet       Date:  1974-04-20       Impact factor: 79.321

5.  Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone.

Authors:  S R Bloom; C H Mortimer; M O Thorner; G M Besser; R Hall; A Gomez-Pan; V M Roy; R C Russell; D H Coy; A J Kastin; A V Schally
Journal:  Lancet       Date:  1974-11-09       Impact factor: 79.321

6.  Action of growth-hormone-release inhibitory hormone in healthy men and in acromegaly.

Authors:  R Hall; G M Besser; A V Schally; D H Coy; D Evered; D J Goldie; A J Kastin; A S McNeilly; C H Mortimer; C Phenekos; W M Tunbridge; D Weightman
Journal:  Lancet       Date:  1973-09-15       Impact factor: 79.321

7.  Inhibition of insulin secretion by somatostatin.

Authors:  K G Alberti; N J Christensen; S E Christensen; A P Hansen; J Iversen; K Lundbaek; K Seyer-Hansen; H Orskov
Journal:  Lancet       Date:  1973-12-08       Impact factor: 79.321

8.  Growth-hormone release-inhibiting hormone in gastrointestinal and pancreatic D cells.

Authors:  J M Polak; A G Pearse; L Grimelius; S R Bloom
Journal:  Lancet       Date:  1975-05-31       Impact factor: 79.321

9.  Direct inhibition of gastric acid and pepsin secretion by growth-hormone release-inhibiting hormone in cats.

Authors:  A Gomez-Pan; J D Reed; M Albinus; B Shaw; R Hall
Journal:  Lancet       Date:  1975-04-19       Impact factor: 79.321

10.  Direct inhibition of gastric acid by growth-hormone release-inhibiting hormone in dogs.

Authors:  A A Barros D'Sa; S R Bloom; J H Baron
Journal:  Lancet       Date:  1975-04-19       Impact factor: 79.321
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  10 in total

1.  Radioimmunoassay study of hepatic clearance and disappearance half-time of somatostatin and vasoactive intestinal peptide in dogs.

Authors:  J A Chayvialle; P L Rayford; J C Thompson
Journal:  Gut       Date:  1981-09       Impact factor: 23.059

2.  Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin release.

Authors:  T Chiba; T Taminato; S Kadowaki; Y Goto; K Mori; Y Seino; H Abe; K Chihara; S Matsukura; T Fujita; T Kondo
Journal:  Gut       Date:  1980-02       Impact factor: 23.059

3.  The somatostatin/histaminic pathway balance on gastric secretion could be based on a competitive antagonism.

Authors:  J Vatier; C Poitevin; W Riquet; M T Vitre; A Olivier; P Martin; S Bonfils
Journal:  Agents Actions       Date:  1988-07

4.  Inhibition of meal stimulated gastric acid secretion by an octapeptide somatostatin analogue SMS 201-995.

Authors:  J A Olsen; F B Loud; J Christiansen
Journal:  Gut       Date:  1987-04       Impact factor: 23.059

5.  Topography of somatostatin cells in the stomach of the rat: possible functional significance.

Authors:  J Alumets; M Ekelund; H A El Munshid; R Håkanson; I Lorén; F Sundler
Journal:  Cell Tissue Res       Date:  1979-11       Impact factor: 5.249

6.  Is somatostatin a humoral regulator of the endocrine pancreas and gastric acid secretion in man?

Authors:  F B Loud; J J Holst; E Egense; B Petersen; J Christiansen
Journal:  Gut       Date:  1985-05       Impact factor: 23.059

7.  Histamine is able to suppress the inhibitory effect of somatostatin on exogenous gastrin: comparison between extractive antral histamine and synthetic histamine.

Authors:  J Vatier; C Poitevin; J C Robert; S Bonfils
Journal:  Agents Actions       Date:  1983-02

8.  Gastric acid secretion results from antagonistic effects of antral histamine (Antramine) and somatostatin on gastrin.

Authors:  J Vatier; C Poitevin; J C Robert; M T Vitre; B K Nguyen Phuoc; S Bonfils
Journal:  Agents Actions       Date:  1984-10

9.  Utilization of the perfused stomach in anaesthetized rats to study the inhibitory effect of somatostatin in gastric acid secretion.

Authors:  M J Robein; M C de la Mare; J M Dubrasquet; S Bonfils
Journal:  Agents Actions       Date:  1979-12

10.  Duodenal G- and D-cell changes following corticosteroid administration. Immunocytochemical long-term study in guinea pigs.

Authors:  E Xynos; J Vassilakis; K Aroni; C Kittas
Journal:  Klin Wochenschr       Date:  1987-02-02
  10 in total

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