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Literature DB >> 3479797

Structure of the chromosomal chicken progesterone receptor gene.

C S Huckaby¹, O M Conneely, W G Beattie, A D Dobson, M J Tsai, B W O'Malley.

Abstract

We have isolated cosmid clones containing the chromosomal chicken progesterone receptor gene. The gene consists of eight exons and is approximately 38 kilobases long. Individual exons correlate well with conserved functional domains of the receptor molecule. Alternative polyadenylylation in the second intron results in a putative non-hormone-binding protein. The cap site of the gene is heterogeneous over at least 14 base pairs and lies in a very G + C-rich region. The promoter lacks "TATA" and "CAAT" boxes, but CCGCCC motifs exist in the surrounding region.

Entities: Gene Species

Mesh：

Substances：

Year: 1987 PMID： 3479797 PMCID： PMC299546 DOI： 10.1073/pnas.84.23.8380

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

39 in total

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Journal: Mol Endocrinol Date: 1987-08

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