Literature DB >> 3476934

The erg gene: a human gene related to the ets oncogene.

E S Reddy, V N Rao, T S Papas.   

Abstract

We have isolated a cDNA clone representing the complete coding sequence of a human gene named erg, related to the ets oncogene. Nucleotide sequence analysis of this cDNA (4.6 kilobases long) revealed that this gene encodes a 363-residue protein whose predicted amino acid sequence showed a homology of approximately equal to 40% and approximately equal to 70% to two domains corresponding to the 5' and 3' regions of v-ets oncogene, respectively. A 3.2- to 3.6-kilobase and approximately equal to 5-kilobase transcript of the erg gene, which differ in size from those of the previously described Hu-ets 1 and Hu-ets 2 genes, were observed in different cells. These results suggest that the erg gene is a member of the ets oncogene family.

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Year:  1987        PMID： 3476934      PMCID： PMC299022          DOI： 10.1073/pnas.84.17.6131

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  30 in total

1.  Myeloid and erythroid neoplastic responses to avian defective leukemia viruses in chickens and in quail.

Authors:  C Moscovici; J Samarut; L Gazzolo; M G Moscovici
Journal:  Virology       Date:  1981-09       Impact factor: 3.616

2.  Frameshift and intragenic suppressor mutations in a Rous sarcoma provirus suggest src encodes two proteins.

Authors:  G Mardon; H E Varmus
Journal:  Cell       Date:  1983-03       Impact factor: 41.582

3.  New M13 vectors for cloning.

Authors:  J Messing
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

4.  A simple method for displaying the hydropathic character of a protein.

Authors:  J Kyte; R F Doolittle
Journal:  J Mol Biol       Date:  1982-05-05       Impact factor: 5.469

5.  Sequencing end-labeled DNA with base-specific chemical cleavages.

Authors:  A M Maxam; W Gilbert
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

6.  Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene.

Authors:  K Radke; H Beug; S Kornfeld; T Graf
Journal:  Cell       Date:  1982-12       Impact factor: 41.582

7.  Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.

Authors:  M Schwab; K Alitalo; K H Klempnauer; H E Varmus; J M Bishop; F Gilbert; G Brodeur; M Goldstein; J Trent
Journal:  Nature       Date:  1983 Sep 15-21       Impact factor: 49.962

8.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Tripartite structure of the avian erythroblastosis virus E26 transforming gene.

Authors:  M F Nunn; P H Seeburg; C Moscovici; P H Duesberg
Journal:  Nature       Date:  1983 Nov 24-30       Impact factor: 49.962

Review 10.  Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.

Authors:  M Kozak
Journal:  Microbiol Rev       Date:  1983-03
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  58 in total

1.  Dual transforming activities of the FUS (TLS)-ERG leukemia fusion protein conferred by two N-terminal domains of FUS (TLS).

Authors:  H Ichikawa; K Shimizu; R Katsu; M Ohki
Journal:  Mol Cell Biol       Date:  1999-11       Impact factor: 4.272

2.  Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells.

Authors:  Wendell S Fortson; Shubhalaxmi Kayarthodi; Yasuo Fujimura; Huali Xu; Roland Matthews; William E Grizzle; Veena N Rao; Ganapathy K Bhat; E Shyam P Reddy
Journal:  Int J Oncol       Date:  2011-04-21       Impact factor: 5.650

3.  Different binding site requirements for binding and activation for the bipartite enhancer factor EF-1A.

Authors:  G M Bolwig; J T Bruder; P Hearing
Journal:  Nucleic Acids Res       Date:  1992-12-25       Impact factor: 16.971

4.  A positive regulator of the ribosomal protein gene, beta factor, belongs to the ETS oncoprotein family.

Authors:  T Yoganathan; N K Bhat; B H Sells
Journal:  Biochem J       Date:  1992-10-15       Impact factor: 3.857

5.  Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I.

Authors:  S D Gitlin; R Bosselut; A Gégonne; J Ghysdael; J N Brady
Journal:  J Virol       Date:  1991-10       Impact factor: 5.103

6.  Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells.

Authors:  D S Pereira; C Dorrell; C Y Ito; O I Gan; B Murdoch; V N Rao; J P Zou; E S Reddy; J E Dick
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-07       Impact factor: 11.205

7.  Human ETS2 gene on chromosome 21 is not rearranged in Alzheimer disease.

Authors:  N Sacchi; J Nalbantoglu; F R Sergovich; T S Papas
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

Review 8.  The oncogene ERG: a key factor in prostate cancer.

Authors:  P Adamo; M R Ladomery
Journal:  Oncogene       Date:  2015-04-27       Impact factor: 9.867

9.  The clinical role of the PEA3 transcription factor in ovarian and breast carcinoma in effusions.

Authors:  Ben Davidson; Iris Goldberg; Liora Tell; Sophya Vigdorchik; Mark Baekelandt; Aasmund Berner; Gunnar B Kristensen; Reuven Reich; Juri Kopolovic
Journal:  Clin Exp Metastasis       Date:  2004       Impact factor: 5.150

Review 10.  Is it important to decipher the heterogeneity of "normal karyotype AML"?

Authors:  Stephen D Nimer
Journal:  Best Pract Res Clin Haematol       Date:  2008-03       Impact factor: 3.020
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