Literature DB >> 3475570

Modulation of transforming growth factor type beta action by activated ras and c-myc.

E B Leof, J A Proper, H L Moses.   

Abstract

Transfection of C3H/10T1/2 cells with a c-myc gene resulted in the acquisition of responsiveness to transforming growth factor type beta. Cells transfected with an activated H-ras gene or an H-ras and c-myc gene, however, exhibited a transformed morphology and spontaneous soft-agar growth, a phenotype induced reversibly by transforming growth factor type beta in responsive fibroblasts.

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Year:  1987        PMID： 3475570      PMCID： PMC365407          DOI： 10.1128/mcb.7.7.2649-2652.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  19 in total

1.  A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors:  F L Graham; A J van der Eb
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

2.  Potentiation of growth factor activity by exogenous c-myc expression.

Authors:  V Sorrentino; V Drozdoff; M D McKinney; L Zeitz; E Fleissner
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

3.  Comparison of intra- and extracellular transforming growth factors from nontransformed and chemically transformed mouse embryo cells.

Authors:  R F Tucker; M E Volkenant; E L Branum; H L Moses
Journal:  Cancer Res       Date:  1983-04       Impact factor: 12.701

4.  Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.

Authors:  H Land; L F Parada; R A Weinberg
Journal:  Nature       Date:  1983 Aug 18-24       Impact factor: 49.962

5.  New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

Authors:  A B Roberts; M A Anzano; L C Lamb; J M Smith; M B Sporn
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

6.  Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene.

Authors:  L F Parada; C J Tabin; C Shih; R A Weinberg
Journal:  Nature       Date:  1982-06-10       Impact factor: 49.962

7.  Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus.

Authors:  E H Chang; M E Furth; E M Scolnick; D R Lowy
Journal:  Nature       Date:  1982-06-10       Impact factor: 49.962

8.  Mouse embryonic transforming growth factors related to those isolated from tumor cells.

Authors:  D R Twardzik; J E Ranchalis; G J Todaro
Journal:  Cancer Res       Date:  1982-02       Impact factor: 12.701

9.  High efficiency DNA-mediated transformation of primate cells.

Authors:  C Gorman; R Padmanabhan; B H Howard
Journal:  Science       Date:  1983-08-05       Impact factor: 47.728

10.  Transforming growth factor production by chemically transformed cells.

Authors:  H L Moses; E L Branum; J A Proper; R A Robinson
Journal:  Cancer Res       Date:  1981-07       Impact factor: 12.701
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  9 in total

1.  Role of a tumor-suppressor gene in the negative control of anchorage-independent growth of Syrian hamster cells.

Authors:  M Koi; C A Afshari; L A Annab; J C Barrett
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

2.  In vitro effects of bone- and platelet-derived transforming growth factor-beta on the growth of Walker 256 carcinosarcoma cells.

Authors:  W Millar-Book; F W Orr; G Singh
Journal:  Clin Exp Metastasis       Date:  1990 Nov-Dec       Impact factor: 5.150

3.  Polyomavirus middle tumor antigen increases responsiveness to growth factors.

Authors:  L Raptis
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

4.  Transforming growth factor beta 1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s).

Authors:  P H Howe; E B Leof
Journal:  Biochem J       Date:  1989-08-01       Impact factor: 3.857

5.  Aberrations of growth factor control in metastatic follicular thyroid cancer in vitro.

Authors:  T Hoelting; A Zielke; A E Siperstein; O H Clark; Q Y Duh
Journal:  Clin Exp Metastasis       Date:  1994-07       Impact factor: 5.150

6.  Three cell lines showing androgen-dependent, -independent, and -suppressed phenotypes, established from a single tumor of androgen-dependent Shionogi carcinoma 115.

Authors:  T Yamaguchi; K Kawamoto; N Uchida; K Uchida; S Watanabe
Journal:  In Vitro Cell Dev Biol       Date:  1992-04

Review 7.  Biology of pancreatic cancer.

Authors:  G J Poston; J Gillespie; P J Guillou
Journal:  Gut       Date:  1991-07       Impact factor: 23.059

8.  Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

Authors:  M G Alexandrow; M Kawabata; M Aakre; H L Moses
Journal:  Proc Natl Acad Sci U S A       Date:  1995-04-11       Impact factor: 11.205

Review 9.  Response modification in carcinogenesis.

Authors:  P A Cerutti
Journal:  Environ Health Perspect       Date:  1989-05       Impact factor: 9.031
  9 in total

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