Literature DB >> 3475034

Effect of food on enoxacin absorption.

A A Somogyi, F Bochner, J A Keal, P E Rolan, M Smith.   

Abstract

Fifteen subjects received a single 400-mg oral dose of enoxacin in the fasting state and after carbohydrate and high-fat meals. The carbohydrate meal delayed the time to peak enoxacin concentration in plasma by an average of 0.92 h. The extent of enoxacin absorption was not altered by food.

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Year:  1987        PMID: 3475034      PMCID: PMC174796          DOI: 10.1128/AAC.31.4.638

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  7 in total

1.  High-performance liquid chromatography and preliminary pharmacokinetics of enoxacin and its 4-oxo metabolite in human plasma, urine and saliva.

Authors:  T B Vree; A M Baars; W J Wijnands
Journal:  J Chromatogr       Date:  1985-10-11

Review 2.  Interactions affecting drug absorption.

Authors:  P G Welling
Journal:  Clin Pharmacokinet       Date:  1984 Sep-Oct       Impact factor: 6.447

3.  Determination of a new antibacterial agent (AT-2266) and its metabolites in plasma and urine by high-performance liquid chromatography.

Authors:  R Nakamura; T Yamaguchi; Y Sekine; M Hashimoto
Journal:  J Chromatogr       Date:  1983-12-09

Review 4.  Fluorinated quinolones. A review of their mode of action, antimicrobial activity, pharmacokinetics and clinical efficacy.

Authors:  R Janknegt
Journal:  Pharm Weekbl Sci       Date:  1986-02-21

5.  Ofloxacin: serum and skin blister fluid pharmacokinetics in the fasting and non-fasting state.

Authors:  T Kalager; A Digranes; T Bergan; T Rolstad
Journal:  J Antimicrob Chemother       Date:  1986-06       Impact factor: 5.790

6.  Effect of standard breakfast on drug absorption and multiple-dose pharmacokinetics of ciprofloxacin.

Authors:  B Ledergerber; J D Bettex; B Joos; M Flepp; R Lüthy
Journal:  Antimicrob Agents Chemother       Date:  1985-03       Impact factor: 5.191

7.  Pharmacokinetics and tissue penetration of enoxacin.

Authors:  R Wise; R Lockley; J Dent; M Webberly
Journal:  Antimicrob Agents Chemother       Date:  1984-07       Impact factor: 5.191

  7 in total
  17 in total

1.  Effect of food on the pharmacokinetics of a single oral dose of moxifloxacin 400mg in healthy male volunteers.

Authors:  J Lettieri; R Vargas; V Agarwal; P Liu
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

2.  The effect of food or milk on the absorption kinetics of ofloxacin.

Authors:  M N Dudley; C R Marchbanks; S C Flor; B Beals
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

3.  Effect of food on absorption of lomefloxacin.

Authors:  W D Hooper; R G Dickinson; M J Eadie
Journal:  Antimicrob Agents Chemother       Date:  1990-09       Impact factor: 5.191

Review 4.  Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  J M Henwood; J P Monk
Journal:  Drugs       Date:  1988-07       Impact factor: 9.546

5.  Effects of milk and food on the absorption of enoxacin.

Authors:  P Lehto; K T Kivistö
Journal:  Br J Clin Pharmacol       Date:  1995-02       Impact factor: 4.335

6.  Effect of enteral feeding with ensure on oral bioavailabilities of ofloxacin and ciprofloxacin.

Authors:  B A Mueller; D G Brierton; S R Abel; L Bowman
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

Review 7.  Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections.

Authors:  S S Patel; C M Spencer
Journal:  Drugs       Date:  1996-01       Impact factor: 9.546

Review 8.  Fluoroquinolones: interaction profile during enteral absorption.

Authors:  K M Deppermann; H Lode
Journal:  Drugs       Date:  1993       Impact factor: 9.546

9.  Effect of a fat- and calcium-rich breakfast on pharmacokinetics of fleroxacin administered in single and multiple doses.

Authors:  J S Bertino; A N Nafziger; M Wong; L Stragand; C Puleo
Journal:  Antimicrob Agents Chemother       Date:  1994-03       Impact factor: 5.191

10.  Effects of traditional Chinese medicines on pharmacokinetics of levofloxacin.

Authors:  T Hasegawa; K Yamaki; I Muraoka; M Nadai; K Takagi; T Nabeshima
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

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