Literature DB >> 3474130

Cloning and sequence analysis of simian transforming growth factor-beta cDNA.

K Sharples, G D Plowman, T M Rose, D R Twardzik, A F Purchio.   

Abstract

We have isolated a cDNA clone coding for the simian TGF-beta precursor from a cDNA library made from an African green monkey cell line, BSC-40. The deduced amino acid sequence of the mature simian TGF-beta shows 100% homology with that of the human TGF-beta: Strong sequence homology was found between the precursor regions of the human and simian proteins with only five amino acid changes out of 278. The simian (and murine) precursor sequence was found to code for one less amino acid residue than the human. The implications of these results with respect to the isolation of a growth inhibitor from these cells functionally related to the TGF-beta molecule are discussed.

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Year:  1987        PMID： 3474130     DOI： 10.1089/dna.1987.6.239

Source DB:  PubMed          Journal:  DNA        ISSN： 0198-0238


  22 in total

Review 1.  Review of the activation of TGF-beta in immunity.

Authors:  Andrew W Taylor
Journal:  J Leukoc Biol       Date:  2008-09-25       Impact factor: 4.962

2.  cDNA cloning by PCR of rat transforming growth factor beta-1.

Authors:  S W Qian; P Kondaiah; A B Roberts; M B Sporn
Journal:  Nucleic Acids Res       Date:  1990-05-25       Impact factor: 16.971

Review 3.  The Discovery and Early Days of TGF-β: A Historical Perspective.

Authors:  Harold L Moses; Anita B Roberts; Rik Derynck
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-07-01       Impact factor: 10.005

4.  Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide.

Authors:  L E Gentry; M N Lioubin; A F Purchio; H Marquardt
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272

5.  Recombinant type 1 transforming growth factor beta precursor produced in Chinese hamster ovary cells is glycosylated and phosphorylated.

Authors:  A M Brunner; L E Gentry; J A Cooper; A F Purchio
Journal:  Mol Cell Biol       Date:  1988-05       Impact factor: 4.272

6.  Enhanced antimycobacterial response to recombinant Mycobacterium bovis BCG expressing latency-associated peptide.

Authors:  B G Marshall; A Wangoo; P O'Gaora; H T Cook; R J Shaw; D B Young
Journal:  Infect Immun       Date:  2001-11       Impact factor: 3.441

7.  A GC-rich domain with bifunctional effects on mRNA and protein levels: implications for control of transforming growth factor beta 1 expression.

Authors:  L Scotto; R K Assoian
Journal:  Mol Cell Biol       Date:  1993-06       Impact factor: 4.272

8.  Development of a retroviral vector for inducible expression of transforming growth factor beta 1.

Authors:  M L McGeady; P M Arthur; M Seidman
Journal:  J Virol       Date:  1990-07       Impact factor: 5.103

9.  Type 1 transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells.

Authors:  L E Gentry; N R Webb; G J Lim; A M Brunner; J E Ranchalis; D R Twardzik; M N Lioubin; H Marquardt; A F Purchio
Journal:  Mol Cell Biol       Date:  1987-10       Impact factor: 4.272

10.  Structural characterization of the latent complex between transforming growth factor beta 1 and beta 1-latency-associated peptide.

Authors:  G A McMahon; J D Dignam; L E Gentry
Journal:  Biochem J       Date:  1996-01-01       Impact factor: 3.857
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